Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jennifer B Hall"'
Publikováno v:
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 2:99-112
Decreased toxicity via selective delivery of cancer therapeutics to tumors has become a hallmark achievement of nanotechnology. In order to be optimally efficacious, a systemically administered nanomedicine must reach cancer cells in sufficient quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac20a448a69f095109ecb96872aa4d09
https://doi.org/10.1002/wnan.66
https://doi.org/10.1002/wnan.66
Autor:
Scott E. McNeil, Parag Aggarwal, Marina A. Dobrovolskaia, Jennifer B. Hall, Christopher B. McLeland
Publikováno v:
Advanced Drug Delivery Reviews. 61:428-437
Proteins bind the surfaces of nanoparticles, and biological materials in general, immediately upon introduction of the materials into a physiological environment. The further biological response of the body is influenced by the nanoparticle-protein c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0952d383b493eae8fb7240ec1d81b071
https://doi.org/10.1016/j.addr.2009.03.009
https://doi.org/10.1016/j.addr.2009.03.009
Autor:
Anil K. Patri, Scott E. McNeil, Jennifer B. Hall, Barry W. Neun, Marina A. Dobrovolskaia, Jeffrey D. Clogston
Publikováno v:
Nano Letters. 8:2180-2187
Hemolysis (destruction of red blood cells) in vivo can lead to anemia, jaundice and other pathological conditions, therefore the hemolytic potential of all intravenously administered pharmaceuticals must be evaluated. Nanotechnology-derived devices a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd60ba42859cb34703df1f7aa2bf2d4e
https://doi.org/10.1021/nl0805615
https://doi.org/10.1021/nl0805615
Publikováno v:
Nanomedicine. 2:789-803
Nanotechnology offers many advantages to traditional drug design, delivery and medical diagnostics; however, nanomedicines present considerable challenges for preclinical development. Nanoparticle constructs intended for medical applications consist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0e31acfe7b5b9b99b6f325ad025ee1
https://doi.org/10.2217/17435889.2.6.789
https://doi.org/10.2217/17435889.2.6.789
Publikováno v:
Journal of Biomolecular NMR. 31:149-154
A new approach is described for measuring chemical shift anisotropy (CSA)/dipolar cross-correlated relaxation (CCR) rates based on the selection of the individual 15N doublet components prior to the relaxation period. The method uses the spin-state-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783f1ca08dca2d963d92770d29f672f8
https://doi.org/10.1007/s10858-004-7562-8
https://doi.org/10.1007/s10858-004-7562-8
Autor:
Jennifer B. Hall, David Fushman
Publikováno v:
Journal of Biomolecular NMR. 27:261-275
Because the overall tumbling provides a major contribution to protein spectral densities measured in solution, the choice of a proper model for this motion is critical for accurate analysis of protein dynamics. Here we study the overall and backbone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a1c017114e53c60bc06b3c5b801c7a8
https://doi.org/10.1023/a:1025467918856
https://doi.org/10.1023/a:1025467918856
Publikováno v:
Journal of Biomolecular NMR. 26:181-186
Here we propose a method for the measurement of the 15N CSA/dipolar relaxation interference based on direct comparison of the 15N doublet components observed in a 1H-coupled 1H-15N HSQC-type spectrum. This allows the determination of the cross-correl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3cfbd0c812e30a307de716df5a0528f
https://doi.org/10.1023/a:1023546107553
https://doi.org/10.1023/a:1023546107553
Autor:
Jennifer B. Hall, David Fushman
Publikováno v:
Magnetic Resonance in Chemistry. 41:837-842
We describe direct methods for the measurement of the transverse and longitudinal 15N chemical shift anisotropy–dipolar cross-correlation rates based on comparison of the 15N doublet components observed in 1H-coupled 1H–15N HSQC-type spectra. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::172e01ee8203ae55ad3a60f7ee7aebc8
https://doi.org/10.1002/mrc.1253
https://doi.org/10.1002/mrc.1253
Autor:
Sara S. Hook, Justin Hanes, Jennifer B Hall, Fatih M. Uckun, Jeff W.M. Bulte, Andrew Z. Wang, Anil K. Patri, Russell J. Mumper, Demir Akin, Nastaran Gharkholo, Michael S. Goldberg, Vincent L. Cryns
Biotargeted nanomedicines have captured the attention of academic and industrial scientists who have been motivated by the theoretical possibilities of the ‘magic bullet’ that was first conceptualized by Paul Ehrlich at the beginning of the 20th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::844c31432aff71a200df995cc833742f
Autor:
Jan Simak, Anil K. Patri, Jennifer B. Hall, Scott E. McNeil, Marina A. Dobrovolskaia, Silvia H. De Paoli Lacerda, Jana Semberova
Publikováno v:
Molecular pharmaceutics. 9(3)
Nanoparticles are finding growing applications in medicine because they may reduce toxicity and improve the solubility, pharmacokinetics and biodistribution profiles1 of traditional pharmaceuticals. In the bloodstream, nanoparticles encounter a very
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973bc1c8819acf4bb1313a84166d5769
https://pubmed.ncbi.nlm.nih.gov/22026635
https://pubmed.ncbi.nlm.nih.gov/22026635