Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Jennifer B, Marks"'
Autor:
Kevan C. Herold, Peter A. Gottlieb, Louis H. Philipson, James Dziura, David A. Baidal, Ruth S. Weinstock, Jason L. Gaglia, Rodica Pop-Busui, Jennifer B. Marks, Stephen E. Gitelman, Jesse Reynolds
Publikováno v:
Diabetes, obesity & metabolism, vol 22, iss 11
Diabetes Obes Metab
Diabetes Obes Metab
AIMS: To test whether a long-acting GLP-1 receptor agonist would improve glucose control in patients with type 1 diabetes (T1D) and to determine whether the presence of residual beta cell function would affect the response. In addition, we sought to
Autor:
David A Baidal, Megan Warnock, Ping Xu, Susan Geyer, Jennifer B Marks, Antoinette Moran, Jay Sosenko, Carmella Evans-Molina
Publikováno v:
J Clin Endocrinol Metab
Context Decreased first-phase insulin response (FPIR) during intravenous glucose tolerance testing (IVGTT) is an early indicator of β-cell dysfunction and predictor of type 1 diabetes (T1D). Objective Assess whether oral glucose tolerance test (OGTT
Autor:
Kevan C, Herold, Brian N, Bundy, S Alice, Long, Jeffrey A, Bluestone, Linda A, DiMeglio, Matthew J, Dufort, Stephen E, Gitelman, Peter A, Gottlieb, Jeffrey P, Krischer, Peter S, Linsley, Jennifer B, Marks, Wayne, Moore, Antoinette, Moran, Henry, Rodriguez, William E, Russell, Desmond, Schatz, Jay S, Skyler, Eva, Tsalikian, Diane K, Wherrett, Anette-Gabriele, Ziegler, Carla J, Greenbaum, Stuart, Weinzimer
Publikováno v:
The New England journal of medicine, vol 381, iss 7
BackgroundType 1 diabetes is a chronic autoimmune disease that leads to destruction of insulin-producing beta cells and dependence on exogenous insulin for survival. Some interventions have delayed the loss of insulin production in patients with type
Autor:
Antoinette Moran, S. Alice Long, Susan Geyer, Megan V. Warnock, Linda A. DiMeglio, Henry Rodriguez, Jennifer B. Marks, Dorothy J. Becker, David A. Baidal, J Lori Blanchfield, Darrell M. Wilson, Peter A. Gottlieb, Stephen E. Gitelman, Desmond A. Schatz, Brian N. Bundy, Jessica L. Miller, Mark A. Atkinson, Michael J. Haller, Jay S. Skyler, Carla J. Greenbaum, Robin Goland, Jeffrey P. Krischer, Kevan C. Herold, William E. Russell
Publikováno v:
Diabetes
A three-arm, randomized, double-masked, placebo-controlled phase 2b trial performed by the Type 1 Diabetes TrialNet Study Group previously demonstrated that low-dose anti-thymocyte globulin (ATG) (2.5 mg/kg) preserved β-cell function and reduced HbA
Autor:
Louis H. Philipson, James Dziura, Peter A. Gottlieb, David A. Baidal, Ruth S. Weinstock, Jesse Reynolds, Jason L. Gaglia, Stephen E. Gitelman, Kevan C. Herold, Rodica Pop-Busui, Jennifer B. Marks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c9e5a6845cf96f4621e5b92a4f89fa6
https://doi.org/10.1111/dom.14121/v2/response1
https://doi.org/10.1111/dom.14121/v2/response1
Autor:
Jennifer B. Marks, Mario A Cleves, Dorothy J. Becker, Jerry P. Palmer, Ingrid Libman, Ping Xu, Heba M. Ismail, Jay S. Skyler, Jay M. Sosenko
Publikováno v:
Diabetes Care
OBJECTIVE Glucose response curves (GRCs) during oral glucose tolerance tests (OGTTs) are predictive of type 1 diabetes. We performed a longitudinal analysis in pancreatic autoantibody-positive individuals to assess 1) characteristic GRC changes durin
Autor:
Peter A. Gottlieb, Mark A. Atkinson, Brian N. Bundy, Darrell M. Wilson, Dorothy J. Becker, Desmond A. Schatz, Stephen E. Gitelman, Antoinette Moran, Jessica L. Miller, Michael J. Haller, David A. Baidal, Carla J. Greenbaum, Robin Goland, Jay S. Skyler, Linda A. DiMeglio, William E. Russell, Jeffrey P. Krischer, Kevan C. Herold, Henry Rodriguez, Jennifer B. Marks
OBJECTIVE A pilot study suggested that combination therapy with low-dose anti-thymocyte globulin (ATG) and pegylated granulocyte colony-stimulating factor (GCSF) preserves C-peptide in established type 1 diabetes (T1D) (duration 4 months to 2 years).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0c05731019ce5e7ad0d122d865c8fa
https://europepmc.org/articles/PMC6105329/
https://europepmc.org/articles/PMC6105329/
Autor:
Jay S. Skyler, Jennifer B. Marks, Ingrid Libman, Jay M. Sosenko, Dorothy J. Becker, Heba M. Ismail, Ping Xu, Jerry P. Palmer
Publikováno v:
Diabetes. 67
Individuals with a biphasic (BP; two peaks) GRC during a 2-hour oral glucose tolerance test (OGTT) are at lower risk of T1D than those with monophasic (MP; one peak) and monotonic (MT; continuous increase) GRCs. We thus performed a longitudinal analy
Autor:
Jay M. Sosenko, D. J. Becker, Kevan C. Herold, E. Leschek, James W. Thomas, Francesco Dotta, Jeffrey L. Mahon, K. Nanto-Salonen, Diane K. Wherrett, Lisa M. Spain, Andrew Muir, Polly J. Bingley, Massimo Trucco, Jeffrey P. Krischer, S. E. Gitelman, Alessandra Mandelli, Mark S. Anderson, Sarah J. Richardson, Peter S. Linsley, Riccardo Bonfanti, Eleonora Bianconi, George S. Eisenbarth, M. Siegelman, J. Peyman, Angela Stabilini, M. Redondo, Bernhard J. Hering, Richard A. Insel, Maurizio De Pellegrin, Franco Meschi, Francesca Ragogna, Mark A. Clements, Lars Krogvold, Mark Peakman, Alberto Pugliese, J. Blum, William E. Russell, P. Chase, Pia Leete, Anette-Gabriele Ziegler, Mark A. Atkinson, Jane H. Buckner, Andrea Rigamonti, Tihamer Orban, Laura Nigi, Philip Raskin, Guido Sebastiani, Louis H. Philipson, Linda A. DiMeglio, Clara Bonura, Manuela Battaglia, Jay S. Skyler, David A. Baidal, Giulio Frontino, Emanuele Bosi, Matthew J. Dufort, Andrea Valle, William E. Winter, Peter A. Gottlieb, C. G. Fathman, Helena Elding Larsson, Robin Goland, Michael J. Clare-Salzler, M. G. Roncarolo, Raphael Clynes, Peter A. Antinozzi, Andrea K. Steck, Mikael Knip, Olli Simell, R. Parkman, Bart O. Roep, Desmond A. Schatz, Henry Rodriguez, Nicola Lo Buono, John M. Wentworth, Andrea Laurenzi, Francesca Mancarella, P. Savage, Jennifer B. Marks, G. Grave, Paola M.V. Rancoita, Federica Vecchio, Åke Lernmark, Darrell M. Wilson, Noel G. Morgan, Thomas W.H. Kay, Francine R. Kaufman, Federica Cugnata, Christophe Benoist, Susan Geyer, Peter G. Colman, Mark D. Pescovitz, Robert S. Sherwin, Gerald T. Nepom, John E. Wagner, Antoinette Moran, Knut Dahl-Jørgensen, Jerry P. Palmer, Kasia Bourcier, Wayne V. Moore, Carla J. Greenbaum, Pauline Grogan
BACKGROUND. Neutrophils and their inflammatory mediators are key pathogenic components in multiple autoimmune diseases, while their role in human type 1 diabetes (T1D), a disease that progresses sequentially through identifiable stages prior to the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee5d8b12a49d70a6a58dc2174c69799
Autor:
Roberto Bizzotto, Maria Laura Manca, Alex Gonzalez, Barry E. Hurwitz, Steven R. Smith, Jay S. Skyler, Neil Schneiderman, Jennifer B. Marks, Maria M. Llabre, Ele Ferrannini, Eleonora Santini, Armando J. Mendez, Andrea Mari
Publikováno v:
Diabetes
High-carbohydrate diets have been associated with β-cell strain, dyslipidemia, and endothelial dysfunction. We examined how β-cell and endothelial function adapt to carbohydrate overloading and the influence of insulin resistance. On sequential day