Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jennifer Alexander‐Brett"'
Autor:
Ella Katz-Kiriakos, Deborah F. Steinberg, Colin E. Kluender, Omar A. Osorio, Catie Newsom-Stewart, Arjun Baronia, Derek E. Byers, Michael J. Holtzman, Dawn Katafiasz, Kristina L. Bailey, Steven L. Brody, Mark J. Miller, Jennifer Alexander-Brett
Publikováno v:
JCI Insight, Vol 6, Iss 4 (2021)
IL-33 is a key mediator of chronic airway disease driven by type 2 immune pathways, yet the nonclassical secretory mechanism for this cytokine remains undefined. We performed a comprehensive analysis in human airway epithelial cells, which revealed t
Externí odkaz:
https://doaj.org/article/29001148d51348f79a6b151d3ea730a7
Autor:
Guy Hazan, Anna Eubanks, Carrie Gierasch, Jeffrey Atkinson, Carolyn Fox, Ariel Hernandez-Leyva, Anne L. Rosen, Andrew L. Kau, Eugene Agapov, Jennifer Alexander-Brett, Deborah Steinberg, Diane Kelley, Michael White, Derek Byers, Kangyun Wu, Shamus P. Keeler, Yong Zhang, Jeffrey R. Koenitzer, Elise Eiden, Neil Anderson, Michael J. Holtzman, Jeffrey Haspel
Publikováno v:
J Immunol
Asthma is a chronic disease of childhood, but for unknown reasons, disease activity sometimes subsides as children mature. In this study, we present clinical and animal model evidence suggesting that the age dependency of childhood asthma stems from
Autor:
Elbert P. Trulock, Bahaa Bedair, Ruben G. Nava, Jennifer Alexander-Brett, Chad A. Witt, Andrew E. Gelman, L.K. Tague, Derek E. Byers, Rodrigo Vazquez-Guillamet, Hrishikesh S. Kulkarni, Ramsey R. Hachem, Daniel Kreisel, Varun Puri
Publikováno v:
J Heart Lung Transplant
BACKGROUND: Mechanical ventilation immediately after lung transplantation may impact the development of primary graft dysfunction (PGD), particularly in cases of donor-recipient size mismatch as ventilation is typically based on recipient rather than
Autor:
Meltem Barlin, Petra Erdmann-Gilmore, Jacqueline L. Mudd, Qiang Zhang, Robert W. Seymour, Zhanfang Guo, Julia R. Miessner, S. Peter Goedegebuure, Ye Bi, Omar A. Osorio, Jennifer Alexander-Brett, Shunqiang Li, Cynthia X. Ma, Ryan C. Fields, R. Reid Townsend, Jason M. Held
Publikováno v:
Molecularcellular proteomics : MCP. 22(1)
Cancer-derived extracellular vesicles (EVs) promote tumorigenesis, premetastatic niche formation, and metastasis via their protein cargo. However, the proteins packaged by patient tumors into EVs cannot be determined in vivo because of the presence o
Autor:
Erika C. Crouch, Christy Hoffmann, Samantha A. Morris, Jennifer Alexander-Brett, Stephen P Austin, Derek E. Byers, Kuangying Yang, Matthew Wallace, Kenji Kamimoto, Yong Zhang, Eugene Agapov, Shamus P. Keeler, Benjamin J. Gerovac, Michael J. Holtzman, Michael E. Hughes, Jennifer Yantis, Kelly A Gissy, Kangyun Wu
Publikováno v:
J Clin Invest
Epithelial cells are charged with protection at barrier sites, but whether this normally beneficial response might sometimes become dysfunctional still needs definition. Here, we recognized a pattern of imbalance marked by basal epithelial cell growt
Autor:
Yonghui Zhao, Hongzhen Hu, Changxiong J. Guo, Oshri Avraham, Aaron M. Ver Heul, Jing Feng, Asima Badic, Dean W. Coble, Jennifer Alexander-Brett, Brian S. Kim, Masato Kubo, Zachary K. Ford, Masato Tamari, Satoru Joshita, Landon K. Oetjen, Carina Dehner, Steve Davidson, Anna M. Trier, Avery Fredman, Madison R. Mack, Valeria Cavalli, Robert W. Gereau, Qin Liu
Publikováno v:
J Allergy Clin Immunol
Background Chronic pruritus, or itch, is common and debilitating, but the neuroimmune mechanisms that drive chronic itch are only starting to be elucidated. Recent studies demonstrate that the IL-33 receptor (IL-33R) is expressed by sensory neurons.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fc16774cfd88db5ee2f11812d52786
https://europepmc.org/articles/PMC8934751/
https://europepmc.org/articles/PMC8934751/
Autor:
Nicholas Borcherding, Wentong Jia, Rocky Giwa, Rachael L. Field, John R. Moley, Benjamin J. Kopecky, Mandy M. Chan, Bin Q. Yang, Jessica M. Sabio, Emma C. Walker, Omar Osorio, Andrea L. Bredemeyer, Terri Pietka, Jennifer Alexander-Brett, Sharon Celeste Morley, Maxim N. Artyomov, Nada A. Abumrad, Joel Schilling, Kory Lavine, Clair Crewe, Jonathan R. Brestoff
Publikováno v:
Cell metabolism. 34(10)
Adipocytes transfer mitochondria to macrophages in white and brown adipose tissues to maintain metabolic homeostasis. In obesity, adipocyte-to-macrophage mitochondria transfer is impaired, and instead, adipocytes release mitochondria into the blood t
Autor:
Jeffrey R. Koenitzer, Anne Rosen, Guy Hazan, Yong Zhang, Carolyn Fox, Michael J. Holtzman, Andrew L. Kau, Shamus P. Keeler, Jeffrey J. Atkinson, Carrie Gierasch, Jennifer Alexander-Brett, Anna Eubanks, Derek E. Byers, Eugene Agapov, Deborah Lynn Steinberg, Diane G. Kelley, Michael White, Jeffrey A. Haspel, Ariel Hernandez-Leyva, Kangyun Wu
Asthma is a common chronic disease of childhood, but for unknown reasons disease activity sometimes subsides as children mature. To understand why, we exposed mice across a range of ages to viral and allergic triggers of asthma exacerbations and airw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58439c9f0ce3a2d38064135fdaeb1f9d
https://doi.org/10.21203/rs.3.rs-544240/v1
https://doi.org/10.21203/rs.3.rs-544240/v1
Autor:
Dawn M. Katafiasz, Catie Newsom-Stewart, Kristina L. Bailey, Derek E. Byers, Steven L. Brody, Michael J. Holtzman, Colin E. Kluender, Arjun Baronia, Jennifer Alexander-Brett, Deborah F. Steinberg, Mark J. Miller, Ella Katz-Kiriakos, Omar A. Osorio
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 4 (2021)
JCI Insight, Vol 6, Iss 4 (2021)
IL-33 is a key mediator of chronic airway disease driven by type 2 immune pathways, yet the nonclassical secretory mechanism for this cytokine remains undefined. We performed a comprehensive analysis in human airway epithelial cells, which revealed t
Autor:
D. Steinberg, Shin-Cheng Tzeng, Bradley S. Evans, E. Katz, Jennifer Alexander-Brett, Colin E. Kluender, E. Roberson
Publikováno v:
B63. EXPLORING COPD BY MARKER, MECHANISM, AND SIGNATURES.