Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jennifer A. Yano"'
Autor:
Marit W. Vermunt, Jing Luan, Zhe Zhang, A. Josephine Thrasher, Anran Huang, Megan S. Saari, Eugene Khandros, Robert A. Beagrie, Shiping Zhang, Pranay Vemulamada, Matilda Brilleman, Kiwon Lee, Jennifer A. Yano, Belinda M. Giardine, Cheryl A. Keller, Ross C. Hardison, Gerd A. Blobel
Publikováno v:
Molecular Cell. 83:715-730.e6
Autor:
Nicole Hamagami, Michael T. Werner, Jennifer A. Yano, Sarah C. Hsu, Hongxin Wang, Aaron J. Stonestrom, Gerd A. Blobel, Yichen Zhong, Vivek Behera, Joel P. Mackay
Publikováno v:
Journal of Biological Chemistry. 295:1898-1914
The widely expressed bromodomain and extraterminal motif (BET) proteins bromodomain-containing protein 2 (BRD2), BRD3, and BRD4 are multifunctional transcriptional regulators that bind acetylated chromatin via their conserved tandem bromodomains. Sma
Autor:
Malini Sharma, Kunhua Qin, Xianjiang Lan, Gerd A. Blobel, Junwei Shi, Jennifer A. Yano, Belinda Giardine, Scott A. Peslak, Ross C. Hardison, Eugene Khandros, Peng Huang, Osheiza Abdulmalik, Cheryl A. Keller
Publikováno v:
Blood
Reactivation of fetal hemoglobin remains a critical goal in the treatment of patients with sickle cell disease and β-thalassemia. Previously, we discovered that silencing of the fetal γ-globin gene requires the erythroid-specific eIF2α kinase heme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda9ca0351e1b81a50a9a69534e5c30c
https://europepmc.org/articles/PMC7290097/
https://europepmc.org/articles/PMC7290097/
Autor:
Michael T. Werner, Hongxin Wang, Nicole Hamagami, Sarah C. Hsu, Jennifer A. Yano, Aaron J. Stonestrom, Vivek Behera, Yichen Zhong, Joel P. Mackay, Gerd A. Blobel
Publikováno v:
J Biol Chem
The widely expressed bromodomain and extraterminal motif (BET) proteins bromodomain-containing protein 2 (BRD2), BRD3, and BRD4 are multifunctional transcriptional regulators that bind acetylated chromatin via their conserved tandem bromodomains. Sma
Autor:
Ross C. Hardison, Xianjiang Lan, Jennifer A. Yano, Scott A. Peslak, Eugene Khandros, Peng Huang, Cheryl A. Keller, Gerd A. Blobel, Junwei Shi, Osheiza Abdulmalik, Grevet Jeremy
Publikováno v:
Blood. 134:3557-3557
Increasing fetal hemoglobin (HbF) provides significant clinical benefit for patients with sickle cell disease (SCD) and is a critical goal that is being pursued with a variety of pharmacologic strategies. Hydroxyurea (HU) is currently the only FDA-ap