Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jennifer A. Stover"'
Autor:
Cathie Leister, Joseph Boni, Gregor Bender, Fred Immermann, Natalie C. Twine, Virginia Fitzpatrick, Michael E. Burczynski, Jennifer Ann Stover, Andrew J. Dorner
Publikováno v:
Clinical Pharmacology & Therapeutics. 77:76-89
Objective Our objective was to estimate the pharmacokinetic parameters of CCI-779 and its metabolite, sirolimus, and evaluate associations of exposure parameters with safety and clinical activity. Exposure parameters were also correlated with pharmac
Autor:
Marc Feldmann, Debra D. Pittman, Jonathan T Beech, Brian M. J. Foxwell, Jennifer A. Stover, Jeffrey L. Feldman, William L. Trepicchio, Christopher J Edwards, Kathleen M. Shields, Glenn Larsen, Fionula M. Brennan
Publikováno v:
Molecular medicine (Cambridge, Mass.). 13(1-2)
Rheumatoid arthritis (RA) is a chronic inflammatory arthritis. Currently, diagnosis of RA may take several weeks, and factors used to predict a poor prognosis are not always reliable. Gene expression in RA may consist of a unique signature. Gene expr
Autor:
Natalie C, Twine, Jennifer A, Stover, Bonnie, Marshall, Gary, Dukart, Manuel, Hidalgo, Walter, Stadler, Theodore, Logan, Janice, Dutcher, Gary, Hudes, Andrew J, Dorner, Donna K, Slonim, William L, Trepicchio, Michael E, Burczynski
Publikováno v:
Cancer research. 63(18)
Expression profiling has demonstrated that transcriptomes of primary malignancies differ from those in normal tissue. It is unknown, however, whether there exist "surrogate" transcriptional markers in peripheral blood mononuclear cells (PBMCs) of pat
Autor:
Andrew J. Dorner, Gregor Bender, Cathie Leister, Fred Immermann, Virginia Fitzpatrick, Joseph Boni, Natalie C. Twine, Michael E. Burczynski, Jennifer Ann Stover
Publikováno v:
Clinical Pharmacology & Therapeutics. 75:P41
CCI-779 (CCI) is a novel mTOR kinase inhibitor being developed for treatment of various cancers. In this randomized, double-blind, multicenter trial, 25, 75, or 250 mg IV CCI was given once weekly to 110 patients with renal cancer and was shown to be