Brain-wide cellular resolution imaging of Cre transgenic zebrafish lines for functional circuit-mapping

Autor: Kathryn M Tabor, Gregory D Marquart, Christopher Hurt, Trevor S Smith, Alexandra K Geoca, Ashwin A Bhandiwad, Abhignya Subedi, Jennifer L Sinclair, Hannah M Rose, Nicholas F Polys, Harold A Burgess

Publikováno v: eLife, Vol 8 (2019)

Decoding the functional connectivity of the nervous system is facilitated by transgenic methods that express a genetically encoded reporter or effector in specific neurons; however, most transgenic lines show broad spatiotemporal and cell-type expres

Externí odkaz: https://doaj.org/article/74c9f141b3f740a6879be9d3a9f04ed7

Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines

Autor: Ariane Pereira, Jeff A. Stogsdill, Gesine Saher, Peter Scheiffele, Lisa Traunmüller, Klaus-Armin Nave, Jiexin Wang, Chris J. McBain, Naosuke Hoshina, Huda Y. Zoghbi, Yu Itoh-Maruoka, Cagla Eroglu, Wei-Hsiang Huang, Fritz Benseler, Thomas Philips, Constance L. Cepko, Mateusz C. Ambrozkiewicz, Jeremy N. Kay, Hiroshi Kawabe, Vania F. Prado, Kevin T. Beier, Wenjia You, Nils Brose, Harold A. Burgess, Wei Lu, Junko Motohashi, Pascal S. Kaeser, Liqun Luo, Marco A. M. Prado, Elisabetta Furlanis, Emily Ling-Lin Pai, Kenji Sakimura, Kenji Mandai, John L.R. Rubenstein, Andrea M. Gomez, Emilie Dumontier, Michisuke Yuzaki, Hisashi Umemori, Yoshimi Takai, Jean-François Cloutier, Susanne Falkner, Laura A. Lavery, Sandra Goebbels, Matthijs Verhage, Ann Marie Craig, Cui Chen, Kenneth A. Pelkey, Wei Li, Nashat Abumaria, Joshua R. Sanes, Lin Luo, Jeffrey D. Rothstein, Joke Wortel, Jennifer L. Sinclair, Mary Anne Hutchison, Tomohiko Maruo

Publikováno v: Neuron, vol 106, iss 1
Luo, L, Ambrozkiewicz, M C, Benseler, F, Chen, C, Dumontier, E, Falkner, S, Furlanis, E, Gomez, A M, Hoshina, N, Huang, W H, Hutchison, M A, Itoh-Maruoka, Y, Lavery, L A, Li, W, Maruo, T, Motohashi, J, Pai, E L L, Pelkey, K A, Pereira, A, Philips, T, Sinclair, J L, Stogsdill, J A, Traunmüller, L, Wang, J, Wortel, J, You, W, Abumaria, N, Beier, K T, Brose, N, Burgess, H A, Cepko, C L, Cloutier, J F, Eroglu, C, Goebbels, S, Kaeser, P S, Kay, J N, Lu, W, Luo, L, Mandai, K, McBain, C J, Nave, K A, Prado, M A M, Prado, V F, Rothstein, J, Rubenstein, J L R, Saher, G, Sakimura, K, Sanes, J R, Scheiffele, P, Takai, Y, Umemori, H, Verhage, M, Yuzaki, M, Zoghbi, H Y, Kawabe, H & Craig, A M 2020, ' Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines : Prevalence of Germline Recombination and Influencing Factors ', Neuron, vol. 106, no. 1, pp. 37-65.e5 . https://doi.org/10.1016/j.neuron.2020.01.008
Neuron, 106(1), 37-65.e5. Cell Press
Neuron

The Cre-loxP system is invaluable for spatial and temporal control of gene knockout, knockin, and reporter expression in the mouse nervous system. However, we report varying probabilities of unexpected germline recombination in distinct Cre driver li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a0d62fde17242aab3eee01b2747766
https://doi.org/10.1016/j.neuron.2020.01.008

Brain-wide cellular resolution imaging of Cre transgenic zebrafish lines for functional circuit-mapping

Autor: Jennifer L. Sinclair, Harold A. Burgess, Trevor Smith, Kathryn M. Tabor, Ashwin A. Bhandiwad, Christopher Hurt, Gregory D. Marquart, Alexandra K Geoca, Nicholas F. Polys, Abhignya Subedi

Decoding the functional connectivity of the nervous system is facilitated by transgenic methods that express a genetically encoded reporter or effector in specific neurons; however, most transgenic lines show broad spatiotemporal and cell-type expres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084295a803ced9ae76e329a785f926b7
https://doi.org/10.1101/444075

Ideation to Execution

Autor: Jennifer L. Sinclair, Priya Shilpa Boindala, Denise Natasha Brewley

In this chapter, a flipped model is implemented in an undergraduate mathematics course. There is a need to enhance learning experiences in STEM disciplines and college mathematics courses. The authors seek to redefine the traditional relationship of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d26bfd1320e9da7afbba4abe8a464d
https://doi.org/10.4018/978-1-5225-1803-7.ch019

A generalization result regarding the small and large scale behavior of infinitely divisible processes

Autor: Jennifer L. Sinclair

Publikováno v: Journal of Mathematical Analysis and Applications. 398:239-253

General conditions for normalized, time-scaled stochastic integrals of independently scattered Levy random measures to converge to a limit are described. The idea is to provide general conditions to bypass the use of characteristic functions, which c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d28d06b0a7357abf51ef848564f0e97c
https://doi.org/10.1016/j.jmaa.2012.08.039