Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jennifer A. Mietla"'
Autor:
Dayanjan S. Wijesinghe, Matthew Brentnall, Jennifer A. Mietla, L. Alexis Hoeferlin, Robert F. Diegelmann, Lawrence H. Boise, Charles E. Chalfant
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 7, Pp 1298-1309 (2014)
In these studies, the role of ceramide-1-phosphate (C1P) in the wound-healing process was investigated. Specifically, fibroblasts isolated from mice with the known anabolic enzyme for C1P, ceramide kinase (CERK), ablated (CERK−/− mice) and their
Externí odkaz:
https://doaj.org/article/1f04c900f5be4d8db8490fe4b8a97873
Autor:
Jennifer A. Mietla, Dayanjan S. Wijesinghe, L. Alexis Hoeferlin, Michael D. Shultz, Ramesh Natarajan, Alpha A. Fowler, III, Charles E. Chalfant
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 7, Pp 1834-1847 (2013)
Multiple reports have demonstrated a role for ceramide kinase (CERK) in the production of eicosanoids. To examine the effects of the genetic ablation of CERK on eicosanoid synthesis, primary mouse embryonic fibroblasts (MEFs) and macrophages were iso
Externí odkaz:
https://doaj.org/article/a30ded6a40ac416fa96f06995d6eb613
Autor:
Brian A. Shapiro, Charles E. Chalfant, Ngoc T. Vu, Adly Yacoub, Mazen M. Gouda, Jacqueline C. Shultz, Michael D. Shultz, Jennifer A. Mietla, Margaret A. Park, Paul Dent, Paul B. Fisher
Publikováno v:
Journal of Biological Chemistry. 291:21669-21681
Melanoma differentiation-associated gene 7 (MDA-7/IL-24) exhibits cytotoxic effects on tumor cells while sparing untransformed cells, and Bcl-x(L) is reported to efficiently block the induction of cell death by MDA-7/IL-24. The expression of Bcl-x(L)
Autor:
Lauren Alexis Hoeferlin, Scott A. Sell, Charles E. Chalfant, Dayanjan S. Wijesinghe, Jason Tucker, Quoc K. Huynh, Jennifer A. Mietla
Publikováno v:
Advances in Wound Care. 4:100-109
Objective: Platelet-rich plasma (PRP) is a popular choice for the treatment of chronic wounds. Current dogma attributes these healing properties to the peptide growth factors of PRP. However, PRP is also rich in bioactive lipids whose contribution to
Autor:
Jennifer A. Mietla, L. Alexis Hoeferlin, Charles E. Chalfant, Dayanjan S. Wijesinghe, Matthew Brentnall, Lawrence H. Boise, Robert F. Diegelmann
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 7, Pp 1298-1309 (2014)
Journal of Lipid Research
Journal of Lipid Research
In these studies, the role of ceramide-1-phosphate (C1P) in the wound-healing process was investigated. Specifically, fibroblasts isolated from mice with the known anabolic enzyme for C1P, ceramide kinase (CERK), ablated (CERK(-/-) mice) and their wi
Autor:
Alpha A. Fowler, Ramesh Natarajan, Charles E. Chalfant, Michael D. Shultz, Jennifer A. Mietla, L. Alexis Hoeferlin, Dayanjan S. Wijesinghe
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 7, Pp 1834-1847 (2013)
Multiple reports have demonstrated a role for ceramide kinase (CERK) in the production of eicosanoids. To examine the effects of the genetic ablation of CERK on eicosanoid synthesis, primary mouse embryonic fibroblasts (MEFs) and macrophages were iso
Autor:
Robert V. Stahelin, Nadia F. Lamour, Charles E. Chalfant, Katherine E. Ward, Jennifer A. Mietla, Dayanjan S. Wijesinghe
Publikováno v:
The Journal of Biological Chemistry
Background: Pro-TNFα is transformed into the active/soluble form through proteolysis by TNFα-converting enzyme (TACE). Results: Genetic ablation of ceramide kinase induces an increase in TACE activity and secreted TNFα. Conclusion: Ceramide 1-phos
Autor:
Nadia F, Lamour, Dayanjan S, Wijesinghe, Jennifer A, Mietla, Katherine E, Ward, Robert V, Stahelin, Charles E, Chalfant
Publikováno v:
The Journal of biological chemistry.
This manuscript was withdrawn by the author.
Autor:
Charles E. Chalfant, Jinhua Wu, Dayanjan S. Wijesinghe, Xianjun Fang, Jennifer A. Mietla, Abir Mukherjee, Eric K. Mayton
Publikováno v:
Analytical Methods. 3:2822
Lysophosphatidic acid (LPA) is a bioactive lipid with a plethora of biological functions including roles in cell survival, proliferation, and migration. Although high-performance liquid chromatography electrospray ionization tandem mass spectrometry