Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Jennifer A. Mertz"'
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
This file contains the following: source data for the graphs shown in Figure 3A (GI50, Z sub G1, and Z G1 increase); source data for the heatmap and graph shown in Figure 3B (expression fold change, log2 fold change, and gene score); qPCR source data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40fa3455abc8c42632cc94f85959ac3d
https://doi.org/10.1158/0008-5472.22409192
https://doi.org/10.1158/0008-5472.22409192
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
This file contains 4 supplementary tables: Table S1 provides the expression values of the indicated genes (RMA) in BETi sensitive and insensitive cell lines; Table S2 shows the enrichment of subtypes of cell lines following selection with the indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d00d1e4e57a5da6c3a1586537c1f6b2
https://doi.org/10.1158/0008-5472.22409195
https://doi.org/10.1158/0008-5472.22409195
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
This file contains the legends for the six supplementary figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b8f2e2a9b9f1fb87de3e92f609882b
https://doi.org/10.1158/0008-5472.22409201
https://doi.org/10.1158/0008-5472.22409201
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
This file contains six supplementary figures: Figure S1 (related to Figure 1) provides additional characterization of the BETi tolerant cell lines; Figure S2 (related to Figure 1) provides additional information regarding gene expression changes in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b310678d015766b4818364e2e8ed04f2
https://doi.org/10.1158/0008-5472.22409198.v1
https://doi.org/10.1158/0008-5472.22409198.v1
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
Small-molecule inhibitors of the bromodomain and extraterminal (BET) family of proteins are being tested in clinical trials for a variety of cancers, but patient selection strategies remain limited. This challenge is partly attributed to the heteroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9d6cdbfe556f14c97575ca1740b94a
https://doi.org/10.1158/0008-5472.c.6507722
https://doi.org/10.1158/0008-5472.c.6507722
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
This file contains the source of all cell lines used for the work described in the manuscript as well as the methods by which cell lines are authenticated at the repositories.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c89307cf9062e93ea40dc522f080c0
https://doi.org/10.1158/0008-5472.22409207
https://doi.org/10.1158/0008-5472.22409207
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
This file contains source data for the graph in Figure 4A (GI50 and expression values for each of the genes in 245 cell lines).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d051679d26f00707b4f38175b0dad4f
https://doi.org/10.1158/0008-5472.22409186.v1
https://doi.org/10.1158/0008-5472.22409186.v1
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
This file contains additional information regarding the methods used in the manuscript, including shRNA sequences, peptide and antibody information, and details about analysis methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c01e20df5bfd541aa5f3cf92fe38bb
https://doi.org/10.1158/0008-5472.22409204.v1
https://doi.org/10.1158/0008-5472.22409204.v1
Autor:
Jennifer A. Mertz, Stefan A. Kirov, Kaylyn E. Williamson, Marton Munz, Robert J. Sims, Michaela Bowden
Publikováno v:
Cancer Research. 83:2802-2802
Targeting lineage-defined transcription factors with small molecules is a proven and effective therapeutic strategy, as demonstrated by estrogen and androgen receptor therapies for breast and prostate cancers. Expression of the transcription factor P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaa071772dc09815fb58abaa91efc5c9
https://doi.org/10.1158/1538-7445.am2023-2802
https://doi.org/10.1158/1538-7445.am2023-2802
Autor:
Andrew R Conery, Richard C Centore, Adrianne Neiss, Patricia J Keller, Shivangi Joshi, Kerry L Spillane, Peter Sandy, Charlie Hatton, Eneida Pardo, Laura Zawadzke, Archana Bommi-Reddy, Karen E Gascoigne, Barbara M Bryant, Jennifer A Mertz, Robert J Sims III
Publikováno v:
eLife, Vol 5 (2016)
Externí odkaz:
https://doaj.org/article/0ea297e6ae5f467d80133d7259ae7025