Výsledky vyhledávání - "Jennifer A. Landers"

Genetic and chemical modulation of spastin-dependent axon outgrowth in zebrafish embryos indicates a role for impaired microtubule dynamics in hereditary spastic paraplegia

Autor: Richard Butler, Jennifer A. Landers, Vincent T. Cunliffe, Jonathan D. Wood

Publikováno v: Disease Models & Mechanisms. 3:743-751

SUMMARY Mutations in the SPAST (SPG4) gene, which encodes the microtubule-severing protein spastin, are the most common cause of autosomal dominant hereditary spastic paraplegia (HSP). Following on from previous work in our laboratory showing that sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77a5d32c4fa8ee71aac15797de21b20
https://doi.org/10.1242/dmm.004002

Zobrazit plný text záznamu

The microtubule-severing protein Spastin is essential for axon outgrowth in the zebrafish embryo

Autor: Jennifer A. Landers, Lisa J. Gleadall, Pamela J. Shaw, Jonathan D. Wood, Megan Bingley, Vickie Thomas-McArthur, Vincent T. Cunliffe, Christopher J McDermott

Publikováno v: Human molecular genetics. 15(18)

Hereditary spastic paraplegia (HSP) is a collection of neurological disorders characterized by developmental failure or degeneration of motor axons in the corticospinal tract and progressive lower limb spasticity. SPG4 mutations are the most common c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e749e8d58a8ccc357304274febac0f
https://pubmed.ncbi.nlm.nih.gov/16893913

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání