Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jennifer A. Kricker"'
Autor:
Jon Petur Joelsson, Jennifer A. Kricker, Ari J. Arason, Snaevar Sigurdsson, Bryndis Valdimarsdottir, Fridrik Runar Gardarsson, Clive P. Page, Fredrik Lehmann, Thorarinn Gudjonsson, Saevar Ingthorsson
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background The airway epithelium (AE) forms the first line of defence against harmful particles and pathogens. Barrier failure of the airway epithelium contributes to exacerbations of a range of lung diseases that are commonly treated with A
Externí odkaz:
https://doaj.org/article/68af876a3a5d4feaab0da207655852e8
Autor:
Ari Jon Arason, Jon Petur Joelsson, Bryndis Valdimarsdottir, Snaevar Sigurdsson, Alexander Gudjonsson, Skarphedinn Halldorsson, Freyr Johannsson, Ottar Rolfsson, Fredrik Lehmann, Saevar Ingthorsson, Paulina Cherek, Gudmundur H. Gudmundsson, Fridrik R. Gardarsson, Clive P. Page, Olafur Baldursson, Thorarinn Gudjonsson, Jennifer A. Kricker
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-19 (2019)
Abstract Background Azithromycin (Azm) is a macrolide recognized for its disease-modifying effects and reduction in exacerbation of chronic airway diseases. It is not clear whether the beneficial effects of Azm are due to its anti-microbial activity
Externí odkaz:
https://doaj.org/article/c8da4be92fa246189c8660fe3fd024d1
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2068 (2022)
The plasticity of responses to drugs is an ever-present confounding factor for all aspects of pharmacology, influencing drug discovery and development, clinical use and the expectations of the patient. As an introduction to this Special Issue of the
Externí odkaz:
https://doaj.org/article/dc787bf058d44eada61698f7bc1ae2b7
Autor:
Jennifer A. Kricker, Clive P. Page, Fridrik Runar Gardarsson, Michael J. Parnham, Olafur Baldursson, Thorarinn Gudjonsson
Publikováno v:
Pharmacological Reviews
Macrolides are among the most widely prescribed broad spectrum antibacterials, particularly for respiratory infections. It is now recognized that these drugs, in particular azithromycin, also exert time-dependent immunomodulatory actions that contrib
Autor:
Bryndis Valdimarsdottir, Saevar Ingthorsson, Jennifer A. Kricker, Ari Jon Arason, Snaevar Sigurdsson, Fridrik Runar Gardarsson, Clive P. Page, Thorarinn Gudjonsson, Jon Petur Joelsson, Fredrik Lehmann
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Respiratory Research
Respiratory Research
Publisher's version (útgefin grein)
Background: The airway epithelium (AE) forms the first line of defence against harmful particles and pathogens. Barrier failure of the airway epithelium contributes to exacerbations of a range of lung disease
Background: The airway epithelium (AE) forms the first line of defence against harmful particles and pathogens. Barrier failure of the airway epithelium contributes to exacerbations of a range of lung disease
Autor:
Jennifer A. Kricker, Jon Petur Joelsson, Sigurbergur Karason, Saevar Ingthorsson, Thorarinn Gudjonsson
Publikováno v:
Laboratory Animal Research
Laboratory Animal Research, Vol 37, Iss 1, Pp 1-11 (2021)
Laboratory Animal Research, Vol 37, Iss 1, Pp 1-11 (2021)
Ventilator-induced lung injury (VILI) is a serious acute injury to the lung tissue that can develop during mechanical ventilation of patients. Due to the mechanical strain of ventilation, damage can occur in the bronchiolar and alveolar epithelium re
Autor:
Fredrik Lehmann, Jennifer A. Kricker, Clive P. Page, Fridrik Runar Gardarsson, Ari Jon Arason, Jon Petur Joelsson, Thorarinn Gudjonsson, Bryndis Valdimarsdottir, Saevar Ingthorsson
Publikováno v:
Airway pharmacology and treatment.
Azithromycin (AZM) is a macrolide which is effective in the treatment of several airway diseases induced by bacterial or environmental insults. We have previously shown barrier enhancing effects of AZM on airway epithelium (AE). In order to analyze b
Autor:
Jennifer A. Kricker, Sarah Sophie Steinhäuser, Gunnhildur Asta Traustadottir, Saevar Ingthorsson, Zuzana Budkova, Aileen Krueger, Thorarinn Gudjonsson, Erika Morera
Publikováno v:
In Vitro Cellular & Developmental Biology. Animal
Publisher's version (útgefin grein).
Epithelial to mesenchymal transition (EMT) is a developmental event that is hijacked in some diseases such as fibrosis and cancer. In cancer, EMT has been linked to increased invasion and metastasis and is g
Epithelial to mesenchymal transition (EMT) is a developmental event that is hijacked in some diseases such as fibrosis and cancer. In cancer, EMT has been linked to increased invasion and metastasis and is g
Autor:
Jennifer A. Kricker, Eirikur Briem, Thorarinn Gudjonsson, Anna Karen Sigurdardottir, Zuzana Budkova, Bylgja Hilmarsdottir, Magnus K. Magnusson, Gunnhildur Asta Traustadottir, Winston Timp
Publisher's version
MicroRNAs regulate developmental events such as branching morphogenesis, epithelial to mesenchymal transition (EMT) and its reverse process mesenchymal to epithelial transition (MET). In this study, we performed small RNA seq
MicroRNAs regulate developmental events such as branching morphogenesis, epithelial to mesenchymal transition (EMT) and its reverse process mesenchymal to epithelial transition (MET). In this study, we performed small RNA seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f0f4e6cc137801dffdaf631a1b124a
https://hdl.handle.net/20.500.11815/1818
https://hdl.handle.net/20.500.11815/1818