Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jennifer A. Dougan"'
Publikováno v:
Tetrahedron Letters. 51:5787-5790
The H-phosphonate of a derivative of thioctic acid (TA) was synthesised and used to introduce a disulfide moiety at the 5′-end of oligonucleotides. This method overcomes the difficulties experienced with the phosphoramidite approach when employing
Publikováno v:
Nucleic Acids Research
Metallic nanoparticles of gold functionalized with oligonucleotides conventionally use a terminal thiol modification and have been used in a wide range of applications. Although readily available, the oligonucleotide-nanoparticle conjugates prepared
Publikováno v:
Infrared and Raman Spectroscopic Imaging
Autor:
Ainara López Córdoba, Petr V. Gorelkin, Sergei G. Kazarian, Wolfgang Schuhmann, Babak Babakinejad, Paolo Actis, Yuri E. Korchev, Elena V. Sviderskaya, Igor V. Yaminsky, David Klenerman, Sofya Mikhaleva, Alexander Erofeev, Andrew Shevchuck, Patrick R. Unwin, Dmitri A. Rusakov, Jan Clausmeyer, Yasufumi Takahashi, Renaud Cornut, Sergiy Tokar, Jennifer A. Dougan, Pavel Novák
Publikováno v:
ACS Nano
ACS Nano, American Chemical Society, 2014, 8, pp.875-884. ⟨10.1021/nn405612q⟩
ACS Nano, 2014, 8, pp.875-884. ⟨10.1021/nn405612q⟩
ACS Nano, American Chemical Society, 2014, 8, pp.875-884. ⟨10.1021/nn405612q⟩
ACS Nano, 2014, 8, pp.875-884. ⟨10.1021/nn405612q⟩
International audience; The measurement of key molecules in individual cells with minimal disruption to the biological milieu is the next frontier in single-cell analyses. Nanoscale devices are ideal analytical tools because of their small size and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9876353583839a9753f8bd859729569d
https://hal.archives-ouvertes.fr/hal-01164088
https://hal.archives-ouvertes.fr/hal-01164088
Autor:
Duncan Graham, Samuel Mabbott, Elon Correa, Jennifer A. Dougan, Kirsten Gracie, Karen Faulds, Royston Goodacre
Publikováno v:
Gracie, K, Correa, E, Mabbott, S, Dougan, J A, Graham, D, Goodacre, R & Faulds, K 2014, ' Simultaneous detection and quantification of three bacterial meningitis pathogens by SERS ', Chemical Science, vol. 5, no. 3, pp. 1030-1040 . https://doi.org/10.1039/c3sc52875h
Bacterial meningitis is well known for its rapid onset and high mortality rates, therefore rapid detection of bacteria found in cerebral spinal fluid (CSF) and subsequent effective treatment is crucial. A new quantitative assay for detection of three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6dc40050553ae362047e4a258ac4f53
https://usir.salford.ac.uk/id/eprint/41371/1/c3sc52875h.pdf
https://usir.salford.ac.uk/id/eprint/41371/1/c3sc52875h.pdf
Publikováno v:
Biochemical Society transactions. 40(4)
SERRS (surface-enhanced resonance Raman scattering) is a vibrational technique, whereby a relatively weak Raman scattering effect is enhanced through the use of a visible chromophore and a roughened metal surface. The direct analysis of DNA by SERRS
Autor:
Danny van Lierop, Duncan Graham, Luca Guerrini, Karen Faulds, Iain A. Larmour, Željka Krpetić, Jennifer A. Dougan
Publikováno v:
Chemical communications (Cambridge, England). 48(66)
Improved positively charged nanoparticles are described to provide a simplified SERS substrate for DNA detection. Complete flocculation of the nanoparticles is prevented due to the controlled analyte induced aggregation. This provides a stable aggreg
Autor:
Karen Faulds, Jennifer A. Dougan
Publikováno v:
The Analyst. 137(3)
The multiplexed detection of biological analytes from complex mixtures is of crucial importance for the future of intelligent management and detection of disease. This review focuses on recent advances in the use of surface enhanced Raman scattering
Publikováno v:
Nanoscale. 3(8)
Metallic nanoparticles functionalized with oligonucleotides are used for a number of nucleic acid detection strategies. However, oligonucleotide-nanoparticle conjugates suffer from a lack of stability when exposed to certain conditions associated wit