Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Jennifer A. Doll"'
Autor:
Sofia Halin, Stina Häggström Rudolfsson, Jennifer A. Doll, Susan E. Crawford, Pernilla Wikström, Anders Bergh
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 4, Pp 336-345 (2010)
Pigment epithelium-derived factor (PEDF) is a potent inhibitor of angiogenesis but whether it has additional effects on the tumor microenvironment is largely unexplored. We show that overexpression of PEDF in orthotopic MatLyLu rat prostate tumors in
Externí odkaz:
https://doaj.org/article/32d407ebc3594ede8b331d49ecfbc51a
Publikováno v:
American Journal of Obstetrics and Gynecology. 226:S94-S95
Autor:
Alice M. Wyrwicz, Jennifer A. Doll, Palamadai N. Venkatasubramanian, Susan E. Crawford, Charles B. Brendler, Gheorghe Iordanescu
Publikováno v:
Journal of Magnetic Resonance Imaging. 42:651-657
Purpose To investigate the association between magnetic resonance (MR) spectroscopically measured fatty acid composition of periprostatic adipose tissue and pathological markers of prostate cancer aggressiveness. Materials and Methods Periprostatic a
Autor:
Gina Morgan, Alice M. Wyrwicz, Charles B. Brendler, Palamadai N. Venkatasubramanian, Philip Fitchev, Michael McGuire, Beth A. Plunkett, Susan E. Crawford, Mona Cornwell, Jennifer A. Doll
Publikováno v:
The Prostate. 74:326-335
BACKGROUND Obesity, particularly visceral adiposity, confers a worse prognosis for prostate cancer (PCa) patients, and increasing periprostatic adipose (PPA) tissue thickness or density is positively associated with more aggressive disease. However,
Autor:
Jennifer A. Doll, Anders Bergh, Susan E. Crawford, Pernilla Wikström, Sofia Halin, Stina Häggström Rudolfsson
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 4, Pp 336-345 (2010)
Pigment epithelium-derived factor (PEDF) is a potent inhibitor of angiogenesis but whether it has additional effects on the tumor microenvironment is largely unexplored. We show that overexpression of PEDF in orthotopic MatLyLu rat prostate tumors in
Autor:
Jennifer A. Doll, Christine A. Shugrue, Chuhan Chung, Mona Cornwell, Susan E. Crawford, Philip Fitchev, Arijeet K. Gattu
Publikováno v:
Journal of Hepatology. 48:471-478
Anti-angiogenic pigment epithelium-derived factor (PEDF) is a 50 kDa secreted glycoprotein that is highly expressed in hepatocytes. Adipose triglyceride lipase (ATGL), a novel lipase critical for triglyceride metabolism, is a receptor for PEDF. We po
Publikováno v:
Seminars in Thrombosis and Hemostasis. 34:161-169
Increased tissue factor (TF) expression is observed in many types of cancer, associated with more aggressive disease, and in thrombosis. The mechanism by which TF promotes tumor growth remains unclear. Anticoagulation has been shown to result in a tr
Autor:
Jennifer A. Doll, Marybeth Browne, Susan E. Crawford, Robert M. Arensman, Mona Cornwell, Veronica Stellmach, Lisa P. Abramson, Marleta Reynolds
Publikováno v:
Journal of Pediatric Surgery. 41:1351-1356
Purpose Loss of pigment epithelium–derived factor (PEDF), a potent inhibitor of angiogenesis, has been linked to progression of angiogenesis-dependent diseases. We postulated that decreased levels of endogenous PEDF in the kidney creates a tumor pe
Autor:
Hao Wang, Jennifer A. Doll, Keyi Jiang, Jarema S. Czarnecki, Deborah L. Cundiff, Mindy Wilson, Gerald A. Soff, Karen M. Ridge
Publikováno v:
Cancer Research. 66:7211-7215
Angiostatin4.5 (AS4.5) is the product of plasmin autoproteolysis and consists of kringles 1 to 4 and ∼85% of kringle 5. In culture, cancer cell surface globular β-actin mediates plasmin autoproteolysis to AS4.5. We now show that plasminogen binds
Autor:
Hao Wang, Deborah L. Cundiff, Gerald A. Soff, Jennifer A. Doll, Brenda Martone, Keyi Jiang, Alfred Rademaker, Timothy M. Kuzel
Publikováno v:
Clinical Cancer Research. 11:6218-6225
Purpose: Angiostatin4.5 (AS4.5), the endogenous human angiostatin, is derived from plasminogen in a two-step process. A plasminogen activator converts plasminogen to plasmin, then plasmin undergoes autoproteolysis to AS4.5. A free sulfhydryl donor ca