Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jennifer A. Clikeman"'
Publikováno v:
Genetics. 157:1481-1491
DNA double-strand break (DSB) repair in yeast is effected primarily by gene conversion. Conversion can conceivably result from gap repair or from mismatch repair of heteroduplex DNA (hDNA) in recombination intermediates. Mismatch repair is normally v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7e9719c8c957aca20545534f8bdbd0
https://doi.org/10.1093/genetics/157.4.1481
https://doi.org/10.1093/genetics/157.4.1481
Publikováno v:
Genes & Development. 14:360-365
The RecA protein of Escherichia coli, which has crucial roles in homologous recombination, DNA damage repair, induction of the SOS response, and SOS mutagenesis, was found to catalyze assimilation of complementary RNA into a homologous region of a DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6b10dbbde4a9b1f53fddf994c70e040
https://doi.org/10.1101/gad.14.3.360
https://doi.org/10.1101/gad.14.3.360
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 274:H883-H891
Heme iron exacerbates oxidant damage by catalyzing the production of free radicals. Heme oxygenase is the rate-limiting enzyme involved in heme catabolism. An inducible form of heme oxygenase, heme oxygenase-1 (HO-1), is upregulated in oxidant and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3e289e3f2ab14c357502af3121f39b
https://doi.org/10.1152/ajpheart.1998.274.3.h883
https://doi.org/10.1152/ajpheart.1998.274.3.h883
Autor:
Jennifer A. Clikeman, Kimberly S. Paffett, Or Amit, Mark A. Brenneman, Rosa T. Sterk, Jac A. Nickoloff, Yi-Chen Lo
Publikováno v:
Molecular and cellular biology. 26(11)
The repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) is critical for maintaining genome stability and cancer suppression. DSBs are produced by ionizing radiation, genotoxic chemicals, and nucleases and when replication forks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0deff7becbe27aece7252471da2af540
https://pubmed.ncbi.nlm.nih.gov/16705162
https://pubmed.ncbi.nlm.nih.gov/16705162
Publikováno v:
Genetics. 157(2)
DNA double-strand breaks (DSBs) are repaired by homologous recombination (HR) and nonhomologous end-joining (NHEJ). NHEJ in yeast chromosomes has been observed only when HR is blocked, as in rad52 mutants or in the absence of a homologous repair temp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c29c0014db0a832882ea673b8f8883
https://pubmed.ncbi.nlm.nih.gov/11156980
https://pubmed.ncbi.nlm.nih.gov/11156980
Publikováno v:
Mutation research. 461(2)
Transcription stimulates spontaneous homologous recombination, but prior studies have not investigated the effects of transcription on double-strand break (DSB)-induced recombination in yeast. We examined products of five ura3 direct repeat substrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1530997f6b1069c913e6afee533f0fc3
https://pubmed.ncbi.nlm.nih.gov/11018585
https://pubmed.ncbi.nlm.nih.gov/11018585
Autor:
Guru Jot Khalsa, Jac A. Nickoloff, Sarah L. Wheeler, Douglas B. Sweetser, Jennifer A. Clikeman
Spontaneous and double-strand break (DSB)-induced allelic recombination in yeast was investigated in crosses between ura3 heteroalleles inactivated by an HO site and a +1 frameshift mutation, with flanking markers defining a 3.4-kbp interval. In some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc81b78fe4a19d6ee2ecd0d2470b8f8e
https://europepmc.org/articles/PMC1460766/
https://europepmc.org/articles/PMC1460766/
Publikováno v:
The American journal of physiology. 276(5)
Heme oxygenase-1 (HO-1), an enzyme important in protection against oxidant stress, is induced in human vascular endothelial cells by the cytokines tumor necrosis factor-α (TNF-α) and interleukin-1α (IL-1α). However, the signaling mediators that r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd02505e39112a347e4731acb1c9cbb8
https://pubmed.ncbi.nlm.nih.gov/10330231
https://pubmed.ncbi.nlm.nih.gov/10330231
Publikováno v:
Brain research. 603(1)
The calcium channel antagonists verapamil nifedipine and flunarizine all increased the threshold for convulsions induced by N -methyl- d -aspartate in rats. By contrast, only flunarizine blocked the long-term serotonin-depleting effects of 3,4-methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7352630abbdd47e5e8f0b383250eb9
https://pubmed.ncbi.nlm.nih.gov/8095837
https://pubmed.ncbi.nlm.nih.gov/8095837