Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jennifer A. Cairns"'
Autor:
Jopeth Ramis, Robert Middlewick, Francesco Pappalardo, Jennifer T. Cairns, Iain D. Stewart, Alison E. John, Shams-Un-Nisa Naveed, Ramaswamy Krishnan, Suzanne Miller, Dominick E. Shaw, Christopher E. Brightling, Lee Buttery, Felicity Rose, Gisli Jenkins, Simon R. Johnson, Amanda L. Tatler
Publikováno v:
The European respiratory journal. 60(1)
BackgroundAirway smooth muscle (ASM) cells are fundamental to asthma pathogenesis, influencing bronchoconstriction, airway hyperresponsiveness and airway remodelling. The extracellular matrix (ECM) can influence tissue remodelling pathways; however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e59884b03e4680478ad69e2dfc02e8
https://pubmed.ncbi.nlm.nih.gov/34996828
https://pubmed.ncbi.nlm.nih.gov/34996828
Publikováno v:
Hydrobiologia. 592:405-422
Most studies of terrestrial litter decomposition in streams and rivers have used leaves from a single tree species, but leaf packs in streams in eastern North America are usually mixtures of two or more species. Litter mixtures may decay more quickly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f87ebb64848f71dc7936841d877f4406
https://doi.org/10.1007/s10750-007-0778-3
https://doi.org/10.1007/s10750-007-0778-3
Autor:
Steven J. Compton, Andrew F. Walls, Karan-Jane Palmer, Jennifer A. Cairns, Bahjat Al-Ani, Morley D. Hollenberg
Publikováno v:
Journal of Biological Chemistry. 275:39207-39212
Protease-activated receptor 2 (PAR2) is a trypsin-activated member of a family of G-protein-coupled PARs. We have identified a polymorphic form of human PAR2 (PAR(2)F240S) characterized by a phenylalanine to serine mutation at residue 240 within extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d5ee812a2995dfb158782f2e285bac
https://doi.org/10.1074/jbc.m007215200
https://doi.org/10.1074/jbc.m007215200
Publikováno v:
Clinical and Experimental Immunology. 121:31-36
SUMMARYTryptase, the major product of human mast cell activation, is a potent stimulus of vascular leakage and neutrophil accumulation in vivo in animal studies, but the mechanisms of action remain unclear. Using HUVEC cultures we have sought to inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922b13c6ba4b2741f8d24f6d68f012b7
https://doi.org/10.1046/j.1365-2249.2000.01271.x
https://doi.org/10.1046/j.1365-2249.2000.01271.x
Autor:
P. Braquet, J P Kolb, M. Paubert-Braquet, Jennifer A. Cairns, John Gordon, B. Dugas, Jean Michel Mencia-Huerta, N. Paul-Eugène
Publikováno v:
Clinical & Experimental Allergy. 23:317-325
The effect of beta 2-adrenoceptor agonists and interleukin-4 (IL-4) on the CD23 expression on, and release from, the human promonocytic cell line, U 937, was investigated. As assessed by flow cytometry, incubation of U 937 cells in the presence of sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be404f7a5e861a4ab88fd97aa0ad5a9f
https://doi.org/10.1111/j.1365-2222.1993.tb00329.x
https://doi.org/10.1111/j.1365-2222.1993.tb00329.x
Autor:
B. Dugas, John Gordon, Jennifer A. Cairns, A Katria, P. Braquet, Vincent Lagente, David A. Hosford, J. M. Mencia-Huerta, N. Paul-Eugène
Publikováno v:
Clinical Experimental Allergy. 21:268-271
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5025b98b75d0b078e98d7fe6f40050fe
https://doi.org/10.1111/j.1365-2222.1991.tb01740.x
https://doi.org/10.1111/j.1365-2222.1991.tb01740.x
Autor:
Jennifer A. Cairns, Jean-Yves Bonnefoy, Pierre Graber, John R. Gordon, John G. Shields, Kathrin U. Jansen
Publikováno v:
Journal of Receptor Research. 11:507-520
Human CD23 (low affinity receptor for IgE) has been expressed in insect cells (Sf9) using the baculovirus expression system and the baculovirus transfer vector pAc373. Insect cells infected with a recombinant baculovirus coding for CD23 synthesized a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009c8c5bbb6a5894703fece64a3c53d8
https://doi.org/10.3109/10799899109066424
https://doi.org/10.3109/10799899109066424
Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation
Autor:
Katherine Bryant, Hunt Je, Paul S. Thomas, H. Patrick McNeil, Garry C. King, Ke Liu, Ahsan Husain, Nicole E. Jackson, Jennifer A. Cairns, Anusha Hettiaratchi, Hong Wei Wang, Nicodemus Tedla
Publikováno v:
The Journal of biological chemistry. 283(49)
Tryptases are serine proteases that are thought to be uniquely and proteolytically active as tetramers. Crystallographic studies reveal that the active tetramer is a flat ring structure composed of four monomers, with their active sites arranged arou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227905114653216ca766c613c7e6686f
https://pubmed.ncbi.nlm.nih.gov/18854315
https://pubmed.ncbi.nlm.nih.gov/18854315
Autor:
Jose-Manuel Tunon de Lara, Diahn-Warng Perng, Hiran Thabrew, Roger Marthan, Patrick Berger, Steven J. Compton, Alan R. McEuen, Jennifer A. Cairns, Andrew F. Walls
Publikováno v:
Europe PubMed Central
Airway remodeling with smooth muscle cell (SMC) hyperplasia is a feature of chronic asthma. We investigated the potential for tryptase, the major secretory product of human mast cells, to act as a growth factor for human airway SMCs. Because this ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1765d114863994b4759d47d8a54b04
https://pubmed.ncbi.nlm.nih.gov/11509538
https://pubmed.ncbi.nlm.nih.gov/11509538