Výsledky vyhledávání - "Jennifer A Yonkus"

Akademický článek

YAP‐TEAD inhibition is associated with upregulation of an androgen receptor mediated transcription program providing therapeutic escape

Autor: Roberto Alva‐Ruiz, Ryan D. Watkins, Jennifer L. Tomlinson, Jennifer A. Yonkus, Amro M. Abdelrahman, Caitlin B. Conboy, Erik Jessen, Nathan W. Werneburg, Hendrien Kuipers, Jack W. Sample, Gregory J. Gores, Sumera I. Ilyas, Mark J. Truty, Rory L. Smoot

Publikováno v: FEBS Open Bio, Vol 14, Iss 11, Pp 1873-1887 (2024)

Cholangiocarcinoma (CCA) is a highly aggressive form of liver cancer and is an increasing cause of cancer‐related death worldwide. Despite its increasing incidence globally and alarming mortality, treatment options for CCA have largely remained unc

Externí odkaz: https://doaj.org/article/c06dce51bdf6443f86bb9d8ffcc1a4dc

Zobrazit plný text záznamu

Akademický článek

In vivo label-free optical signatures of chemotherapy response in human pancreatic ductal adenocarcinoma patient-derived xenografts

Autor: Jaena Park, Janet E. Sorrells, Eric J. Chaney, Amro M. Abdelrahman, Jennifer A. Yonkus, Jennifer L. Leiting, Heidi Nelson, Jonathan J. Harrington, Edita Aksamitiene, Marina Marjanovic, Peter D. Groves, Colleen Bushell, Mark J. Truty, Stephen A. Boppart

Publikováno v: Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)

Abstract Pancreatic cancer is a devastating disease often detected at later stages, necessitating swift and effective chemotherapy treatment. However, chemoresistance is common and its mechanisms are poorly understood. Here, label-free multi-modal no

Externí odkaz: https://doaj.org/article/caa8ab88d08344c5ae72a4306c96e8da

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

An expeditious and precise method for diameter reduction of venous aneurysm causing arteriovenous fistula steal syndrome

Autor: Jennifer A. Yonkus, MD, Tiziano Tallarita, MD, Indrani Sen, MBBS, Jason Beckermann, MD, Thomas Carmody, MD

Publikováno v: Journal of Vascular Surgery Cases and Innovative Techniques, Vol 9, Iss 2, Pp 101169- (2023)

Clinically significant dialysis access steal syndrome occurs in 1% to 8% of patients. In the present report, we describe an innovative, hybrid option for venoplasty of a cephalic vein aneurysm using a vascular staple device in conjunction with a 6-mm

Externí odkaz: https://doaj.org/article/533efe52a155459292446bbeaa8a4774

Zobrazit plný text záznamu

Akademický článek

SHP2 inhibition enhances Yes-associated protein–mediated liver regeneration in murine partial hepatectomy models

Autor: Ryan D. Watkins, EeeLN H. Buckarma, Jennifer L. Tomlinson, Chantal E. McCabe, Jennifer A. Yonkus, Nathan W. Werneburg, Rachel L. Bayer, Patrick P. Starlinger, Keith D. Robertson, Chen Wang, Gregory J. Gores, Rory L. Smoot

Publikováno v: JCI Insight, Vol 7, Iss 15 (2022)

Disrupted liver regeneration following hepatectomy represents an “undruggable” clinical challenge associated with poor patient outcomes. Yes-associated protein (YAP), a transcriptional coactivator that is repressed by the Hippo pathway, is instru

Externí odkaz: https://doaj.org/article/eddf07034a1b4e00bd8fa09ff333da67

Zobrazit plný text záznamu

Akademický článek

Optimizing Nanopore Sequencing for Rapid Detection of Microbial Species and Antimicrobial Resistance in Patients at Risk of Surgical Site Infections

Autor: Emma Whittle, Jennifer A. Yonkus, Patricio Jeraldo, Roberto Alva-Ruiz, Heidi Nelson, Michael L. Kendrick, Thomas E. Grys, Robin Patel, Mark J. Truty, Nicholas Chia

Publikováno v: mSphere, Vol 7, Iss 1 (2022)

ABSTRACT Surgical site infections (SSI) are a significant burden to patients and health care systems. We evaluated the use of Nanopore sequencing (NS) to rapidly detect microbial species and antimicrobial resistance (AMR) genes present in intraoperat

Externí odkaz: https://doaj.org/article/eb08b3d419b94aebb97a4053c850ef09

Zobrazit plný text záznamu

Patency rates of hepatic arterial resection and revascularization in locally advanced pancreatic cancer

Autor: Roberto Alva-Ruiz, Amro M. Abdelrahman, Patrick P. Starlinger, Jennifer A. Yonkus, David N. Moravec, Joel J. Busch, Chad J. Fleming, James C. Andrews, Bernardo C. Mendes, Jill J. Colglazier, Rory L. Smoot, Sean P. Cleary, David M. Nagorney, Michael L. Kendrick, Mark J. Truty

Publikováno v: HPB. 24:1957-1966

Arterial resection (AR) for pancreatic adenocarcinoma is increasingly considered at specialized centers. We aimed to examine the incidence, risk factors, and outcomes of hepatic artery (HA) occlusion after revascularization.We included patients under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37158bce2294f11ef78d31644efec669
https://doi.org/10.1016/j.hpb.2022.06.005

Zobrazit plný text záznamu

'Answers in hours': A prospective clinical study using nanopore sequencing for bile duct cultures

Autor: Jennifer A. Yonkus, Emma Whittle, Roberto Alva-Ruiz, Amro M. Abdelrahman, Susan E. Horsman, Gina A. Suh, Scott A. Cunningham, Heidi Nelson, Travis E. Grotz, Rory L. Smoot, Sean P. Cleary, David M. Nagorney, Michael L. Kendrick, Robin Patel, Mark J. Truty, Nicholas Chia

Publikováno v: Surgery. 171:693-702

Surgical site infection is a major source of morbidity in patients undergoing pancreatic head resection and is often from organisms in intraoperative bile duct cultures. As such, many institutions use prolonged prophylactic antibiotics and tailor bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fd85e01090250827f82fe933db7ec8
https://doi.org/10.1016/j.surg.2021.09.037

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání