Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Jennifer A Muszynski"'
Autor:
Cynthia A. Moffitt, Peter Olupot-Olupot, Joan Wamulugwa, Julian Abeso, Jennifer A. Muszynski, Nicole O’Brien
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Malaria is the leading cause of hospitalizations and death in Uganda, particularly in children under the age of five. Studies have shown that adherence to the World Health Organization (WHO) guidelines for the management of severe
Externí odkaz:
https://doaj.org/article/247915a744884188914d880e92642a84
Autor:
Mihir R. Atreya, Shayantan Banerjee, Andrew J. Lautz, Matthew N. Alder, Brian M. Varisco, Hector R. Wong, Jennifer A. Muszynski, Mark W. Hall, L. Nelson Sanchez-Pinto, Rishikesan Kamaleswaran, Natalie Z. Cvijanovich, Julie C. Fitzgerald, Scott L. Weiss, Michael T. Bigham, Parag N. Jain, Adam J. Schwarz, Riad Lutfi, Jeffrey Nowak, Geoffrey L. Allen, Neal J. Thomas, Jocelyn R. Grunwell, Torrey Baines, Michael Quasney, Bereketeab Haileselassie, Chris J. Lindsell
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104938- (2024)
Summary: Background: Multiple organ dysfunction syndrome (MODS) disproportionately drives morbidity and mortality among critically ill patients. However, we lack a comprehensive understanding of its pathobiology. Identification of genes associated wi
Externí odkaz:
https://doaj.org/article/162e22e81e7c4a51b9298a80581e6c4c
Autor:
Katherine E. Bline, Melissa Moore-Clingenpeel, Josey Hensley, Lisa Steele, Kristin Greathouse, Larissa Anglim, Lisa Hanson-Huber, Jyotsna Nateri, Jennifer A. Muszynski, Octavio Ramilo, Mark W. Hall
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-7 (2020)
Abstract Background Severe critical illness-induced immune suppression, termed immunoparalysis, is associated with longer duration of organ dysfunction in septic children. mRNA studies have suggested differential benefit of hydrocortisone in septic c
Externí odkaz:
https://doaj.org/article/8ee33637ea3442c9bfd96ae18d8cba0e
Autor:
Andrew Snyder, Kathleen Jedreski, James Fitch, Saranga Wijeratne, Amy Wetzel, Josey Hensley, Margaret Flowers, Katherine Bline, Mark W. Hall, Jennifer A. Muszynski
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundSevere innate immune suppression, termed immunoparalysis, is associated with increased risks of nosocomial infection and mortality in children with septic shock. Currently, immunoparalysis cannot be clinically diagnosed in children, and mec
Externí odkaz:
https://doaj.org/article/e686a6f9e09048279cf9d5fb6957310a
Autor:
Robert T. Russell, Joseph R. Esparaz, Michael A. Beckwith, Peter J. Abraham, Melania M. Bembea, Matthew A. Borgman, Randall S. Burd, Barbara A. Gaines, Mubeen Jafri, Cassandra D. Josephson, Christine Leeper, Julie C. Leonard, Jennifer A. Muszynski, Kathleen K. Nicol, Daniel K. Nishijima, Paul A. Stricker, Adam M. Vogel, Trisha E. Wong, Philip C. Spinella
Publikováno v:
Journal of Trauma and Acute Care Surgery. 94:S2-S10
Hemorrhagic shock in pediatric trauma patients remains a challenging yet preventable cause of death. There is little high-quality evidence available to guide specific aspects of hemorrhage control and specific resuscitation practices in this populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226f5b2947559df34aa4129b296dff41
https://doi.org/10.1097/ta.0000000000003805
https://doi.org/10.1097/ta.0000000000003805
Autor:
Katherine E, Bline, Jennifer A, Muszynski, Adam J, Guess, Somaang, Menocha, Melissa D, Moore-Clingenpeel, Jill K, Popelka, Josey M, Hensley, Lisa M, Steele, Ian C, Goldthwaite, Kathleen J, Jedreski, Mark W, Hall
Publikováno v:
Pediatric Critical Care Medicine. 23:e555-e563
Immunoparalysis in children with septic shock is associated with increased risk of nosocomial infections and death. Myeloid-derived suppressor cells (MDSCs) potently suppress T cell function and may perpetuate immunoparalysis. Our goal was to test th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3317b49c9bf7ec36e9b67e57358d2a80
https://doi.org/10.1097/pcc.0000000000003071
https://doi.org/10.1097/pcc.0000000000003071
Publikováno v:
The Journal of Applied Laboratory Medicine. 7:1108-1119
Background Accurate assessment of hemostatic function is essential to guide care in critically ill children with acute and acquired coagulopathies. Thrombin generation (TG) provides a global assessment of procoagulant and anticoagulant factors and is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56565f6c7bd85bc68db605c0a5e9584
https://doi.org/10.1093/jalm/jfac030
https://doi.org/10.1093/jalm/jfac030
Autor:
Melania M. Bembea, Michael Agus, Ayse Akcan-Arikan, Peta Alexander, Rajit Basu, Tellen D. Bennett, Desmond Bohn, Leonardo R. Brandão, Ann-Marie Brown, Joseph A. Carcillo, Paul Checchia, Jill Cholette, Ira M. Cheifetz, Timothy Cornell, Allan Doctor, Michelle Eckerle, Simon Erickson, Reid W.D. Farris, E. Vincent S. Faustino, Julie C. Fitzgerald, Dana Y. Fuhrman, John S. Giuliano, Kristin Guilliams, Michael Gaies, Stephen M. Gorga, Mark Hall, Sheila J. Hanson, Mary Hartman, Amanda B. Hassinger, Sharon Y. Irving, Howard Jeffries, Philippe Jouvet, Sujatha Kannan, Oliver Karam, Robinder G. Khemani, Niranjan Kissoon, Jacques Lacroix, Peter Laussen, Francis Leclerc, Jan Hau Lee, Stephane Leteurtre, Katie Lobner, Patrick J. McKiernan, Kusum Menon, Paul Monagle, Jennifer A. Muszynski, Folafoluwa Odetola, Robert Parker, Nazima Pathan, Richard W. Pierce, Jose Pineda, Jose M. Prince, Karen A. Robinson, Courtney M. Rowan, Lindsay M. Ryerson, L. Nelson Sanchez-Pinto, Luregn J. Schlapbach, David T. Selewski, Lara S. Shekerdemian, Dennis Simon, Lincoln S. Smith, James E. Squires, Robert H. Squires, Scott M. Sutherland, Yves Ouellette, Michael C. Spaeder, Vijay Srinivasan, Marie E. Steiner, Robert C. Tasker, Ravi Thiagarajan, Neal Thomas, Pierre Tissieres, Chani Traube, Marisa Tucci, Katri V. Typpo, Mark S. Wainwright, Shan L. Ward, R. Scott Watson, Scott Weiss, Jane Whitney, Doug Willson, James L. Wynn, Nadir Yeyha, Jerry J. Zimmerman
Publikováno v:
Pediatrics
Prior criteria for organ dysfunction in critically ill children were based mainly on expert opinion. We convened the Pediatric Organ Dysfunction Information Update Mandate (PODIUM) expert panel to summarize data characterizing single and multiple org
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f8da307efc2410e3bc23f4eec206fc
https://doi.org/10.1542/peds.2021-052888b
https://doi.org/10.1542/peds.2021-052888b
Autor:
Chani, Traube, Marisa, Tucci, Marianne E, Nellis, K Leslie, Avery, Patrick S, McQuillen, Julie C, Fitzgerald, Jennifer A, Muszynski, Jill M, Cholette, Adam J, Schwarz, Erika L, Stalets, Maureen A, Quaid, Sheila J, Hanson, Jacques, Lacroix, Ron W, Reeder, Philip C, Spinella
Publikováno v:
Crit Care Med
OBJECTIVE: Primary objective: to determine if transfusion of short-storage red blood cells (RBCs) compared to standard-issue RBCs reduced risk of delirium/coma in critically ill children. Secondary objective: to assess if RBC transfusion was independ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa723834b233dadbd68a28ebc2c5833
https://pubmed.ncbi.nlm.nih.gov/35100190
https://pubmed.ncbi.nlm.nih.gov/35100190
Autor:
Meghan, Delaney, Oliver, Karam, Lani, Lieberman, Katherine, Steffen, Jennifer A, Muszynski, Ruchika, Goel, Scot T, Bateman, Robert I, Parker, Marianne E, Nellis, Kenneth E, Remy, Michelle, Demetres
Publikováno v:
Pediatr Crit Care Med
To present consensus statements and supporting literature for plasma and platelet product variables and related laboratory testing for transfusions in general critically ill children from the Transfusion and Anemia EXpertise Initiative-Control/Avoida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfac1af7de52a22fbb63b647aac45490
https://pubmed.ncbi.nlm.nih.gov/34989701
https://pubmed.ncbi.nlm.nih.gov/34989701