Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Jennifer A Mitchel"'
Autor:
Shijie He, Christopher V Carman, Jung Hyun Lee, Bo Lan, Stephan Koehler, Lior Atia, Chan Young Park, Jae Hun Kim, Jennifer A Mitchel, Jin-Ah Park, James P Butler, Quan Lu, Jeffrey J Fredberg
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0202065 (2019)
Loss of function of the tumor suppressor p53 is known to increase the rate of migration of cells transiting the narrow pores of the traditional Boyden chamber assay. Here by contrast we investigate how p53 impacts the rate of cellular migration withi
Externí odkaz:
https://doaj.org/article/0c813738fbdd4754afad93fe9c91ffea
Autor:
Jennifer A Mitchel, Diane Hoffman-Kim
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24316 (2011)
Directed migration of Schwann cells (SC) is critical for development and repair of the peripheral nervous system. Understanding aspects of motility specific to SC, along with SC response to engineered biomaterials, may inform strategies to enhance ne
Externí odkaz:
https://doaj.org/article/dd29ca42a8964e3189874598f9cdea76
Publikováno v:
Biology Open. 12
Under homeostatic conditions, epithelial cells remain non-migratory. However, during embryonic development and pathological conditions, they become migratory. The mechanism underlying the transition of the epithelial layer between non-migratory and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec836ecc250f4ab17e42a0879d046737
https://doi.org/10.1242/bio.059727
https://doi.org/10.1242/bio.059727
Under homeostatic conditions, epithelial cells remain non-migratory. However, during embryonic developmental and pathological processes, they become migratory. The mechanism underlying the transition between non-migratory and migratory epithelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a8c1fb9eaec701821e52a5fb6f060d3
https://doi.org/10.1101/2022.08.18.504453
https://doi.org/10.1101/2022.08.18.504453
Autor:
Jennifer A. Mitchel, Michael O'Sullivan, Jin-Ah Park, Maureen McGill, Phyllis J. Kanki, Chimwemwe Mwase
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
Am J Physiol Lung Cell Mol Physiol
Am J Physiol Lung Cell Mol Physiol
The COVID-19 pandemic is an ongoing threat to public health. Since the identification of COVID-19, the disease caused by SARS-CoV-2, no drugs have been developed to specifically target SARS-CoV-2. To develop effective and safe treatment options, a be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956a1c85ef10527b94b1a8d7ddee92c4
https://doi.org/10.1152/ajplung.00423.2020
https://doi.org/10.1152/ajplung.00423.2020
Autor:
Jennifer A. Mitchel, M. Angela Nieto, Stephan A. Koehler, Michael O'Sullivan, Dapeng Bi, Ian T. Stancil, James P. Butler, Jeffrey J. Fredberg, Stephen J. DeCamp, Oscar H. Ocaña, Amit Das, Jin-Ah Park
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which these core programs are distinct, overlapping, or identical has remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28976bbd435fd9c2231943026aa75f3
https://doaj.org/article/ab4af25389c54c6284d0fdfba0eb6c62
https://doaj.org/article/ab4af25389c54c6284d0fdfba0eb6c62
Autor:
Scott T. Weiss, Darren Roblyer, James P. Butler, Muhammad H. Zaman, Stephan A. Koehler, Jennifer A. Mitchel, Stephen J. DeCamp, Nicolas Chiu Ogassavara, Margherita De Marzio, Chan Young Park, John T. Giblin, Jacopo Ferruzzi, Ayşe Kılıç, Jeffrey J. Fredberg, Victor M. K. Tsuda
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
In development of an embryo, healing of a wound, or progression of a carcinoma, a requisite event is collective epithelial cellular migration. For example, cells at the advancing front of a wound edge tend to migrate collectively, elongate substantia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64b8a199d80bd904ee5f5037b1a5dc4
http://link.springer.com/article/10.1038/s41598-020-74992-z
http://link.springer.com/article/10.1038/s41598-020-74992-z
Autor:
Chimwemwe Mwase, Thien-Khoi N. Phung, Michael J. O’Sullivan, Jennifer A. Mitchel, Margherita De Marzio, Ayşe Kılıç, Scott T. Weiss, Jeffrey J. Fredberg, Jin-Ah Park
Publikováno v:
Cells, Vol 11, Iss 256, p 256 (2022)
Cells; Volume 11; Issue 2; Pages: 256
Cells
Cells; Volume 11; Issue 2; Pages: 256
Cells
Aberrant remodeling of the asthmatic airway is not well understood but is thought to be attributable in part to mechanical compression of airway epithelial cells. Here, we examine compression-induced expression and secretion of the extracellular matr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68841dc4678e632121a6dbbefc889ea0
https://www.mdpi.com/2073-4409/11/2/256
https://www.mdpi.com/2073-4409/11/2/256
Autor:
Yasha Sharma, Jacopo Ferruzzi, Muhammad H. Zaman, Jin-Ah Park, Yu Long Han, Jennifer A. Mitchel, Adil Khan, Zi Chen, Wenying Kang, Jeffrey J. Fredberg, Darren Roblyer, Catalina-Paula Spatarelu, Adrian F. Pegoraro, James P. Butler, Ming Guo, Stephan A. Koehler
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103252-(2021)
iScience
iScience
Summary It is well established that the early malignant tumor invades surrounding extracellular matrix (ECM) in a manner that depends upon material properties of constituent cells, surrounding ECM, and their interactions. Recent studies have establis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a833e82117619d0272e1b392dad37a
http://www.sciencedirect.com/science/article/pii/S2589004221012219
http://www.sciencedirect.com/science/article/pii/S2589004221012219
Autor:
Scott T. Weiss, Jennifer A. Mitchel, Chimwemwe Mwase, Jin-Ah Park, Robert P. Chase, Kimberly Glass, Michael O'Sullivan, Enrico Maiorino, Maureen McGill, Ayşe Kılıç, Margherita De Marzio, Jeffrey J. Fredberg
Publikováno v:
Science Advances
Temporal RNA-seq data reveal genomic signatures of the unjamming transition in compressed human bronchial epithelial cells.
Epithelial tissue can transition from a jammed, solid-like, quiescent phase to an unjammed, fluid-like, migratory phase,
Epithelial tissue can transition from a jammed, solid-like, quiescent phase to an unjammed, fluid-like, migratory phase,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38e1e90eae673c3d1c3f0fe3fbed8c5
https://doi.org/10.1126/sciadv.abf1088
https://doi.org/10.1126/sciadv.abf1088