Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Jennifer A DeLeon"'
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Akademický článek
Factors influencing COVID-19 vaccine uptake among Latinos: A cross-sectional study.
Autor: Deborah G Smith, Corey D Smith, Jennifer A DeLeon, Jillian L Sandoz, Carolina O Ochoa, Martha P Pearson, Raimunda H M Macena
Publikováno v: PLoS ONE, Vol 19, Iss 7, p e0302332 (2024)
Vaccination against COVID-19 can prevent severe illness and reduce hospitalizations and deaths. Understanding and addressing determinants contributing to vaccine uptake among high-risk groups, such as Latinos, are pivotal in ensuring equitable vaccin
Externí odkaz: https://doaj.org/article/859f8699decb465b89e56874e3f2e2b8
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5
The VPS-34 PI3 kinase negatively regulates RAB-5 during endosome maturation
Autor: Yousstina Bolis, Fiona Law, Jennifer L. DeLeon, Jung Hwa Seo, Guangwei Du, Ashley Brown, Wei-Xing Zong, Ziqing Wang, Christian E. Rocheleau
Publikováno v: Journal of Cell Science.
The GTPase Rab5 and phosphatidylinositol-3 phosphate [PI(3)P] coordinately regulate endosome trafficking. Rab5 recruits Vps34, the class III phosphoinositide 3-kinase (PI3K), to generate PI(3)P and recruit PI(3)P-binding proteins. Loss of Rab5 and lo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea93048ba4ec71ef1a56bf5c09f0cfc
https://doi.org/10.1242/jcs.194746
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6
Class IA PI3K p110β Subunit Promotes Autophagy through Rab5 Small GTPase in Response to Growth Factor Limitation
Autor: Guangpu Li, Hashem A. Dbouk, Ji-An Pan, Jennifer L. DeLeon, Lisa M. Ballou, Wei-Xing Zong, Richard Z. Lin, Zhimin Liang, Juei Suei Chen, Zhixun Dou, Yongjun Fan, Jonathan M. Backer
Publikováno v: Molecular Cell. 50:29-42
Autophagy is an evolutionarily conserved membrane trafficking process. Induction of autophagy in response to nutrient limitation or cellular stress occurs by similar mechanisms in organisms from yeast to mammals. Unlike yeast, metazoan cells rely mor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fa3f4e60ad17732a1745c23d9f991b
https://doi.org/10.1016/j.molcel.2013.01.022
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7
Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase activating protein Armus
Autor: Nadia Jaber, Seong M. Kim, Jennifer L. DeLeon, Namratha Sheshadri, Hua Zhong, Wei-Xing Zong, Noor Faizah Mohd-Naim, Zhixun Dou, Ziqing Wang, Guangwei Du, Aimee L. Edinger, Vania M.M. Braga
Publikováno v: Journal of Cell Science.
The class III phosphoinositide 3-kinase (PI3K) Vps34 (also known as PIK3C3 in mammals) produces phosphatidylinositol 3-phosphate [PI(3)P] on both early and late endosome membranes to control membrane dynamics. We used Vps34-deficient cells to delinea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f58546fd051b4447880ea87e740691f
https://doi.org/10.1242/jcs.192260
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8
Small-Molecule Anticancer Compounds Selectively Target the Hemopexin Domain of Matrix Metalloproteinase-9
Autor: Jizu Zhi, Antoine Dufour, Nicole S. Sampson, Jian Cao, Cem Kuscu, Nadia Jaber, Eric Minwei Liu, Jian Li, Stanley Zucker, Robert C. Rizzo, Jennifer L. DeLeon
Publikováno v: Cancer Research. 71:4977-4988
Lack of target specificity by existing matrix metalloproteinase (MMP) inhibitors has hindered antimetastatic cancer drug discovery. Inhibitors that bind to noncatalytic sites of MMPs and disrupt protease signaling function have the potential to be mo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fdbef854ce65a6a582dc1656a408e1e
https://doi.org/10.1158/0008-5472.can-10-4552
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