Zobrazeno 1 - 10
of 326
pro vyhledávání: '"Jennifer A Chen"'
Autor:
Jennifer H. Chen, Sridevi Addanki, Dhruvajyoti Roy, Roland Bassett, Ekaterina Kalashnikova, Erik Spickard, Henry M. Kuerer, Salyna Meas, Vanessa N. Sarli, Anil Korkut, Jason B. White, Gaiane M. Rauch, Debu Tripathy, Banu K. Arun, Carlos H. Barcenas, Clinton Yam, Himanshu Sethi, Angel A. Rodriguez, Minetta C. Liu, Stacy L. Moulder, Anthony Lucci
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Triple negative breast cancer (TNBC) is an aggressive subtype with poor prognosis. We aimed to determine whether circulating tumor DNA (ctDNA) and circulating tumor cell (CTC) could predict response and long-term outcomes to neoad
Externí odkaz:
https://doaj.org/article/f34717845d704cca8a1c2809ca2e3328
Autor:
Mahbubul H. Shihan, Sachin Sharma, Carson Cable, Vijaya Prathigudupu, Alina Chen, Aras N. Mattis, Jennifer Y. Chen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Hepatic fibrosis is driven by the activation of hepatic stellate cells (HSCs). The Hippo pathway and its effectors, YAP and TAZ, are key regulators of HSC activation and fibrosis. However, there is a lack of mechanistic understanding of YAP/
Externí odkaz:
https://doaj.org/article/da53c32d081d422e9d8ac3a11c1158ca
Autor:
Wanfen Yip, Sheryl Hui Xian Ng, Palvinder Kaur, Pradeep Paul George, Jennifer Huey Chen Guan, Guozhang Lee, Timothy Jee Kam Koh, Woan Shin Tan, Allyn Yin Mei Hum
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Objectives There is a lack of prognostic information to guide the prediction of short-term all-cause mortality in patients with end-stage renal disease (ESRD). The aim was to review the risk factors that influenced the risk of short-term all
Externí odkaz:
https://doaj.org/article/495f49d7e6144042aea64df115bc2e7b
Autor:
Priyanka Athavale, Robert J. Wong, Derek D. Satre, Alexander Monto, Ramsey Cheung, Jennifer Y. Chen, Steven L. Batki, Michael J. Ostacher, Hannah R. Snyder, Brigita D. Widiarto, Seo Yoon Oh, Meimei Liao, Adele M.L. Viviani, Mandana Khalili
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 2, Pp 201-209 (2024)
Background and Aims: Telehealth has emerged as an important mode of cirrhosis care delivery, but its use and satisfaction among vulnerable populations (eg, racial/ethnic minorities, socioeconomically disadvantaged, substance use disorders) are unknow
Externí odkaz:
https://doaj.org/article/70d5541e08d04c0f8bdc8d12bfd6997b
Autor:
Nicola Alesi, Damir Khabibullin, Dean M. Rosenthal, Elie W. Akl, Pieter M. Cory, Michel Alchoueiry, Samer Salem, Melissa Daou, William F. Gibbons, Jennifer A. Chen, Long Zhang, Harilaos Filippakis, Laura Graciotti, Caterina Miceli, Jlenia Monfregola, Claudia Vilardo, Manrico Morroni, Chiara Di Malta, Gennaro Napolitano, Andrea Ballabio, Elizabeth P. Henske
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Tuberous Sclerosis Complex (TSC) is caused by TSC1 or TSC2 mutations, leading to hyperactivation of mechanistic target of rapamycin complex 1 (mTORC1) and lesions in multiple organs including lung (lymphangioleiomyomatosis) and kidney (angio
Externí odkaz:
https://doaj.org/article/84551f68541142aa9d79d29bb32f55a5
Autor:
Simina Grigoriu, Rachel Bond, Pilar Cossio, Jennifer A Chen, Nina Ly, Gerhard Hummer, Rebecca Page, Martha S Cyert, Wolfgang Peti
Publikováno v:
PLoS Biology, Vol 11, Iss 2, p e1001492 (2013)
Ser/thr phosphatases dephosphorylate their targets with high specificity, yet the structural and sequence determinants of phosphosite recognition are poorly understood. Calcineurin (CN) is a conserved Ca(2+)/calmodulin-dependent ser/thr phosphatase a
Externí odkaz:
https://doaj.org/article/869148b1dc734871b219ca7c467c926b
Publikováno v:
Education Sciences, Vol 14, Iss 10, p 1042 (2024)
Considering that early literacy (reading and writing) is critical for later literacy and academic success, this study investigated the social and contextual influences on the early and current literacy experiences of 70 preservice early childhood tea
Externí odkaz:
https://doaj.org/article/14c9f279b8df4d5297dc6c24fe2a414b
Autor:
Jennifer C Chen, Mark S Aldenderfer, Jelmer W Eerkens, BrieAnna S Langlie, Carlos Viviano Llave, James T Watson, Randall Haas
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0296420 (2024)
Current models of early human subsistence economies suggest a focus on large mammal hunting. To evaluate this hypothesis, we examine human bone stable isotope chemistry of 24 individuals from the early Holocene sites of Wilamaya Patjxa (9.0-8.7 cal.
Externí odkaz:
https://doaj.org/article/054b8f4836004d1d8cdb1030729fe991
Autor:
Sarah MacKinnon, Viviane Pagé, Jennifer J Chen, Ali Shariat-Panahi, Ryan D Martin, Terence E Hébert, Jason C Tanny
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1010492 (2023)
Heterochromatin is a condensed chromatin structure that represses transcription of repetitive DNA elements and developmental genes, and is required for genome stability. Paradoxically, transcription of heterochromatic sequences is required for establ
Externí odkaz:
https://doaj.org/article/dbd12551f7714f75a90c65fa64656856
Autor:
Jennifer S. Chen, Michael J. Murphy, Katelyn Singh, Alice Wang, Ryan D. Chow, Sa Rang Kim, Jeffrey M. Cohen, Christine J. Ko, William Damsky
Publikováno v:
JID Innovations, Vol 3, Iss 4, Pp 100189- (2023)
Acral dermatoses, including hyperkeratotic palmoplantar eczema (HPE), palmoplantar psoriasis (PP), and mycosis fungoides palmaris et plantaris (MFPP), can be challenging to diagnose clinically and histopathologically. In this setting, cytokine biomar
Externí odkaz:
https://doaj.org/article/c84df0b20401449bb6e498fec9e0e197