Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Jennifer, Trieu"'
Autor:
Kristy Swiderski, Timur Naim, Jennifer Trieu, Annabel Chee, Marco J. Herold, Andrew J. Kueh, Craig A. Goodman, Paul Gregorevic, Gordon S. Lynch
Publikováno v:
Physiological Reports, Vol 12, Iss 13, Pp n/a-n/a (2024)
Abstract The dystrophin protein has well‐characterized roles in force transmission and maintaining membrane integrity during muscle contraction. Studies have reported decreased expression of dystrophin in atrophying muscles during wasting condition
Externí odkaz:
https://doaj.org/article/e3f8dce52d1343ea87adfed715477910
Autor:
Kristy Swiderski, Audrey S. Chan, Marco J. Herold, Andrew J. Kueh, Jin D. Chung, Justin P. Hardee, Jennifer Trieu, Annabel Chee, Timur Naim, Paul Gregorevic, Gordon S. Lynch
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/0b8d5a9dc15b471b9c11baee9e4ca30c
Autor:
Francesca M. Alves, Kai Kysenius, Marissa K. Caldow, Justin P. Hardee, Jin D. Chung, Jennifer Trieu, Dominic J. Hare, Peter J. Crouch, Scott Ayton, Ashley I. Bush, Gordon S. Lynch, René Koopman
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1541-1553 (2022)
Abstract Background Oxidative stress is implicated in the pathophysiology of Duchenne muscular dystrophy (DMD, caused by mutations in the dystrophin gene), which is the most common and severe of the muscular dystrophies. To our knowledge, the distrib
Externí odkaz:
https://doaj.org/article/da04fde3e0e44d6e87bd46e1112410fb
Autor:
Kate T. Murphy, Kristy Swiderski, James G. Ryall, Jonathan R. Davey, Hongwei Qian, Séverine Lamon, Victoria C. Foletta, Jennifer Trieu, Annabel Chee, Suzannah J. Read, Timur Naim, Paul Gregorevic, Gordon S. Lynch
Publikováno v:
JCSM Rapid Communications, Vol 5, Iss 1, Pp 102-116 (2022)
Abstract Background Cachexia is a debilitating complication of cancer characterized by progressive wasting and weakness of skeletal muscles that reduces quality of life and can compromise survival. Many anticancer treatments, such as chemotherapy, al
Externí odkaz:
https://doaj.org/article/4b80acbe02104dee8ebddccaedd7c9ba
Autor:
Daniel J. Ham, Anastasia Gardner, Tahnee L. Kennedy, Jennifer Trieu, Timur Naim, Annabel Chee, Francesca M. Alves, Marissa K. Caldow, Gordon S. Lynch, René Koopman
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract Duchenne muscular dystrophy (DMD) is an X-linked genetic disease characterized by progressive muscle wasting and weakness and premature death. Glucocorticoids (e.g. prednisolone) remain the only drugs with a favorable impact on DMD patients,
Externí odkaz:
https://doaj.org/article/6271200ce1974e419391ebe4bea3de4c
Autor:
Francesca M. Alves, Marissa K. Caldow, Jennifer Trieu, Tim Naim, Magdalene K. Montgomery, Matthew J. Watt, Gordon S. Lynch, René Koopman
Publikováno v:
Clinical Nutrition Experimental, Vol 24, Iss , Pp 83-91 (2019)
Summary: Background & aims: Dystrophic muscle fibres are fragile and prone to breakage, leading to impaired Ca2+ homeostasis and excessive inflammation, resulting in muscle wasting and weakness. Choline, an essential water-soluble nutrient, is involv
Externí odkaz:
https://doaj.org/article/72bfb56772184122be201bd75390b68a
Autor:
Wenlan Li, Jennifer Trieu, Ronnie Blazev, Benjamin L. Parker, Kate T. Murphy, Kristy Swiderski, Gordon S. Lynch
Publikováno v:
American Journal of Physiology-Cell Physiology. 324:C205-C221
Cancer cachexia is common in many cancers and the loss of skeletal muscle mass compromises the response to therapies and quality of life. A contributing mechanism is oxidative stress and compounds able to attenuate it may be protective. Sulforaphane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb2b2753a82b96b21ad67f74a382107
https://doi.org/10.1152/ajpcell.00025.2022
https://doi.org/10.1152/ajpcell.00025.2022
Autor:
Marissa K. Caldow, Daniel J. Ham, Jennifer Trieu, Jin Dylan Chung, Gordon S. Lynch, René Koopman
Publikováno v:
Frontiers in Nutrition, Vol 6 (2019)
Glycine supplementation can protect skeletal muscles of mice from cancer-induced wasting, but the mechanisms underlying this protection are not well-understood. The aim of this study was to determine whether exogenous glycine directly protects skelet
Externí odkaz:
https://doaj.org/article/8f347f7f0e8b4cde92560c95f26e8164
Autor:
Kristy Swiderski, Marissa K Caldow, Timur Naim, Jennifer Trieu, Annabel Chee, René Koopman, Gordon S Lynch
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212880 (2019)
Muscles of older animals are more susceptible to injury and regenerate poorly, in part due to a persistent inflammatory response. The janus kinase (Jak)/signal transducer and activator of transcription (Stat) pathway mediates inflammatory signaling a
Externí odkaz:
https://doaj.org/article/f6fe9446f9d741ab87341f0df429af07
Autor:
Gordon S. Lynch, Andrew R. Judge, Jose G. Trevino, Sarah M. Judge, David I. Stapleton, Suzannah J. Read, Vanessa Haynes, Jennifer Trieu, Timur Naim, Annabel Chee, Kristy Swiderski, Mohammed I. Hossain, Kate T. Murphy
This file contains: • Supplemental Methods • Supplemental Figure S1. Muscle-specific overexpression of the AT1 but not the MasR regulates skeletal muscle fiber size in healthy mice. • Supplemental Figure S2. Representative images of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b900cc1b0ac26bfb6a2eea6bd5b6c51
https://doi.org/10.1158/0008-5472.22422416.v1
https://doi.org/10.1158/0008-5472.22422416.v1
