Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jennifer, Philopena"'
Autor:
Van Tsai, Heidrun Engler, Murali Ramachandra, Todd Machemer, Erlinda Quijano, Robert O. Ralston, Jennifer Philopena, Shu-Fen Wen
Publikováno v:
Virology. 328(1):52-61
Replication competent adenoviruses with various E1 modifications designed to restrict their replication to tumor cells are being evaluated as oncolytic agents in clinical trials. In mouse models, we observed that such oncolytic adenoviruses showed gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ade00da62296166452f785176a1dbe
Autor:
Jenny Avanzini, Shu Fen Wen, Mei Vaillancourt, Isabella A. Atencio, Duane E. Johnson, Robert O. Ralston, Wills Ken N, Saskia Neuteboom, Jennifer Philopena, Suganto Sutjipto, Anne Phelan
Publikováno v:
Journal of Virology. 75:8733-8741
In vitro experiments have demonstrated intercellular trafficking of the VP22 tegument protein of herpes simplex virus type 1 from infected cells to neighboring cells, which internalize VP22 and transport it to the nucleus. VP22 also can mediate inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14267232dbda919cb2ba3ebacf7e462d
https://doi.org/10.1128/jvi.75.18.8733-8741.2001
https://doi.org/10.1128/jvi.75.18.8733-8741.2001
Autor:
G William, Demers, Duane E, Johnson, Van, Tsai, Shu-Fen, Wen, Erlinda, Quijano, Todd, Machemer, Jennifer, Philopena, Murali, Ramachandra, John A, Howe, Paul, Shabram, Robert, Ralston, Heidrun, Engler
Publikováno v:
Cancer research. 63(14)
Central to the development of oncolytic virotherapies for cancer will be a better understanding of the parameters that influence the outcome of virotherapy to treat disseminated cancer by i.v. administration versus regional disease by local treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83592a1a8cdfa15617cde3e3c27d355d
https://pubmed.ncbi.nlm.nih.gov/12873998
https://pubmed.ncbi.nlm.nih.gov/12873998
Autor:
Duane E. Johnson, Isabella A. Atencio, Ken N. Wills, Barry J. Sugarman, Loretta L. Nielsen, Gerry Hajian, Jennifer Philopena, Suganto Sutjipto, Mei-Ting Vaillancourt, Margarita Nodelman, Diane McAllister, Saskia Neuteboom, Murali Ramachandra, Jenny B. Avanzini, Josefina C. Beltran
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 4(1)
TP53 is the most commonly altered tumor-suppressor gene in cancer and is currently being tested in Phase II/III gene replacement trials. Many tumors contain wild-type TP53 sequence with elevated MDM2 protein levels, targeting p53 for degradation. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9bcd98d8cedfe66f8b2ba95bb34a210
https://pubmed.ncbi.nlm.nih.gov/11472100
https://pubmed.ncbi.nlm.nih.gov/11472100
Autor:
Jennifer Philopena, Scott C. Anderson, Heidrun Engler, Daniel C. Maneval, Todd Machemer, Robert J. Connor, Shu-Fen Wen
Publikováno v:
Urology. 53(5)
Objectives. Replication deficient adenoviral vectors (rAds) are used as gene delivery systems that can efficiently transduce a variety of tissues and may be appropriate vectors to develop gene therapeutics for many urologic applications. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f4174bacd6078ef9ab56722550b8ca
https://pubmed.ncbi.nlm.nih.gov/10223504
https://pubmed.ncbi.nlm.nih.gov/10223504
Publikováno v:
Journal of Urology. 173:204-205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d05b5b256af6f9da2cf78b8a89af8a2
https://doi.org/10.1016/s0022-5347(18)34922-x
https://doi.org/10.1016/s0022-5347(18)34922-x