Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jennifer, Pfizenmaier"'
Publikováno v:
Biotechnology Journal. 10:1639-1650
Mammalian cells show a compartmented metabolism. Getting access to subcellular metabolite pools is of high interest to understand the cells' metabolomic state. Therefore a protocol is developed and applied for monitoring compartment-specific metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766187857dac526cb66112cfd726fb94
https://doi.org/10.1002/biot.201500060
https://doi.org/10.1002/biot.201500060
Publikováno v:
Biotechnology Progress. 31:1212-1216
A variety of approaches has been published to enhance specific productivity (qp) of recombinant Chinese hamster ovary (CHO) cells. Changes in culture conditions, e. g. temperature shifts, sodium butyrate treatment and hyperosmolality, were shown to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f7a97501defa7a76b6a33c1262bd8c
https://doi.org/10.1002/btpr.2143
https://doi.org/10.1002/btpr.2143
Autor:
Ralf Takors, Jennifer Pfizenmaier
Publikováno v:
Industrial Biotechnology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b515b714dd0a7f5a6e9141386270f75
https://doi.org/10.1002/9783527807796.ch17
https://doi.org/10.1002/9783527807796.ch17
Autor:
Andres, Sánchez-Kopper, Max, Becker, Jennifer, Pfizenmaier, Christian, Kessler, Andreas, Karau, Ralf, Takors
Publikováno v:
AMB Express
Market demands for monoclonal antibodies (mAbs) are steadily increasing worldwide. As a result, production processes using Chinese hamster ovary cells (CHO) are in the focus of ongoing intensification studies for maximizing cell-specific and volumetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c231f6b687a66ed3bd8893448629f7f
https://pubmed.ncbi.nlm.nih.gov/27447702
https://pubmed.ncbi.nlm.nih.gov/27447702
Autor:
Stephan Hofmann, Philipp Koldewey, Guoping Ren, Tim Tapley, Miroslaw Cygler, James C.A. Bardwell, Shu Quan, Nadine Kirsch, Zhaohui Xu, Linda Foit, Karen M. Ruane, Ursula Jakob, Jennifer Pfizenmaier, Rong Shi
Publikováno v:
Nature structural & molecular biology
To optimize the in vivo folding of proteins, we linked protein stability to antibiotic resistance, thereby forcing bacteria to effectively fold and stabilize proteins. When we challenged Escherichia coli to stabilize a very unstable periplasmic prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd23dced89dc73e74cc7ca94b2f1782
http://europepmc.org/articles/PMC3079333
http://europepmc.org/articles/PMC3079333
Publikováno v:
Biotechnology journal. 11(8)
Biopharmaceuticals are predominantly produced by Chinese hamster ovary (CHO) cells cultivated in fed-batch mode. Hyperosmotic culture conditions (≥ 350 mOsmol kg(∑1) ) resulting from feeding of nutrients may enhance specific product formation rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca397f6489c6d9607a539e054ec845b6
https://pubmed.ncbi.nlm.nih.gov/27214792
https://pubmed.ncbi.nlm.nih.gov/27214792