Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jennifer, Olt"'
Autor:
Timothy Erickson, Clive P Morgan, Jennifer Olt, Katherine Hardy, Elisabeth Busch-Nentwich, Reo Maeda, Rachel Clemens, Jocelyn F Krey, Alex Nechiporuk, Peter G Barr-Gillespie, Walter Marcotti, Teresa Nicolson
Publikováno v:
eLife, Vol 6 (2017)
Transmembrane O-methyltransferase (TOMT/LRTOMT) is responsible for non-syndromic deafness DFNB63. However, the specific defects that lead to hearing loss have not been described. Using a zebrafish model of DFNB63, we show that the auditory and vestib
Externí odkaz:
https://doaj.org/article/8c67b3aa4fc342c1bcf127fb9e97b312
Autor:
Jennifer Olt, Jing-Yi Jeng, Matthew C. Holley, Steve D. M. Brown, Stuart L. Johnson, Federico Ceriani, Michael R. Bowl, Walter Marcotti
Publikováno v:
J Physiol
Mammalian cochlear inner hair cells (IHCs) are specialized sensory receptors able to provide dynamic coding of sound signals. This ability is largely conferred by their ribbon synapses, which tether a large number of vesicles at the IHC’s presynapt
Autor:
Kia, Crittenden-Ward, Martina, Micaletto, Jennifer, Olt, Zinan Chen, Tackett, Sayaka, Machizawa, Nicole, Owuor, Todd, Feaster, Rachel, Berman, Prateek, Verma, Nathan, Blubaugh, Rebecca, Laird, Shirley, Kramer
Publikováno v:
Psychiatry research. 308
It is well recognized that underrepresented and systematically minoritized groups do not have balanced access to clinical trials as study participants or as research Investigators. However, comprehensive data on the perspective of expert clinicians i
Autor:
Jennifer Olt, Philomena Mburu, Stuart L Johnson, Andy Parker, Stephanie Kuhn, Mike Bowl, Walter Marcotti, Steve D M Brown
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87331 (2014)
Sound transduction depends upon mechanosensitive channels localized on the hair-like bundles that project from the apical surface of cochlear hair cells. Hair bundles show a stair-case structure composed of rows of stereocilia, and each stereocilium
Externí odkaz:
https://doaj.org/article/18393930fade44d8ab1ae0511d004ddf
Autor:
Kia Crittenden-Ward, Martina Micaletto, Jennifer Olt, Zinan Chen Tackett, Sayaka Machizawa, Nicole Owuor, Todd Feaster, Rachel Berman, Prateek Verma, Nathan Blubaugh, Rebecca Laird, Shirley Kramer
Publikováno v:
Psychiatry Research. 310:114438
Autor:
Kia Crittenden-Ward, Martina Micaletto, Jennifer Olt, Zinan Chen Tackett, Sayaka Machizawa, Nicole Owuor, Todd Feaster, Rachel Berman, Prateek Verma, Nathan Blubaugh, Rebecca Laird, Shirley Kramer
Publikováno v:
Psychiatry Research. 308:114333
Publikováno v:
Epilepsy & Behavior. 124:108324
Objectives Developmental and epileptic encephalopathies (DEEs) are rare neurodevelopmental disorders characterized by early-onset seizures and numerous comorbidities. Due to the complex requirements for the care of a child with a DEE, these disorders
Autor:
Josef G. Trapani, Ya Xian Wang, Teresa Nicolson, Xinyi J. He, Qiuxiang Zhang, Ronald S. Petralia, Alisha Beirl, Jennifer Olt, Lavinia Sheets, Mary Schreck, Walter Marcotti, Katie S. Kindt
Publikováno v:
The Journal of Neuroscience
In sensory hair cells of auditory and vestibular organs, the ribbon synapse is required for the precise encoding of a wide range of complex stimuli. Hair cells have a unique presynaptic structure, the synaptic ribbon, which organizes both synaptic ve
Autor:
Tanaya, Bardhan, Jing-Yi, Jeng, Marco, Waldmann, Federico, Ceriani, Stuart L, Johnson, Jennifer, Olt, Lukas, Rüttiger, Walter, Marcotti, Matthew C, Holley
Publikováno v:
The Journal of Physiology
Key points The physiological maturation of auditory hair cells and their innervation requires precise temporal and spatial control of cell differentiation.The transcription factor gata3 is essential for the earliest stages of auditory system developm
Publikováno v:
The Journal of Physiology. 594:5427-5438
Hair cells are sensory receptors responsible for transducing auditory and vestibular information into electrical signals, which are then transmitted with remarkable precision to afferent neurons. The zebrafish lateral line is emerging as an excellent