Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Jennifer, Major"'
Autor:
Tatyana Bodrug, Elizabeth M Wilson-Kubalek, Stanley Nithianantham, Alex F Thompson, April Alfieri, Ignas Gaska, Jennifer Major, Garrett Debs, Sayaka Inagaki, Pedro Gutierrez, Larisa Gheber, Richard J McKenney, Charles Vaughn Sindelar, Ronald Milligan, Jason Stumpff, Steven S Rosenfeld, Scott T Forth, Jawdat Al-Bassam
Publikováno v:
eLife, Vol 9 (2020)
Kinesin-5 motors organize mitotic spindles by sliding apart microtubules. They are homotetramers with dimeric motor and tail domains at both ends of a bipolar minifilament. Here, we describe a regulatory mechanism involving direct binding between tai
Externí odkaz:
https://doaj.org/article/df2534919cf44fd39e58c822475e8f4e
Autor:
John P. Hirdes, Jennifer Major, Selma Didic, Christine Quinn, Cynthia Sinclair, Jennifer Bucek, Stephen Samis, Micaela Jantzi, Jonathan Chen, Nancy Curtin-Telegdi, Kaye Phillips
Publikováno v:
SAGE Open, Vol 9 (2019)
Antipsychotic use in the absence of symptoms or diagnoses related to psychosis is generally regarded as an inappropriate approach to care of older adults in nursing homes. The Canadian Foundation for Healthcare Improvement (CFHI) launched a pan-Canad
Externí odkaz:
https://doaj.org/article/bab7308b7a244c1fbb8e8c1100469a3f
Autor:
Mary Helmer-Smith, Ariana Mihan, Claire Sethuram, Isabella Moroz, Lois Crowe, Tanya MacDonald, Jennifer Major, Deanne Houghton, James Laplante, Donald Mastin, Lisa Poole, Mary Beth Wighton, Clare Liddy
Publikováno v:
Canadian Journal on Aging / La Revue canadienne du vieillissement. 41:550-564
Dementia is a growing concern in Canada, affecting peoples’ health and raising the cost of care. Between June and October 2019, we conducted an environmental scan to identify primary care models, strategies, and resources for dementia care from 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37600b525927a67188614775f2869e0
https://doi.org/10.1017/s0714980821000635
https://doi.org/10.1017/s0714980821000635
Autor:
Joseph Atherton, I-Mei Yu, Alexander Cook, Joseph M Muretta, Agnel Joseph, Jennifer Major, Yannick Sourigues, Jeffrey Clause, Maya Topf, Steven S Rosenfeld, Anne Houdusse, Carolyn A Moores
Publikováno v:
eLife, Vol 6 (2017)
MKLP2, a kinesin-6, has critical roles during the metaphase-anaphase transition and cytokinesis. Its motor domain contains conserved nucleotide binding motifs, but is divergent in sequence (~35% identity) and size (~40% larger) compared to other kine
Externí odkaz:
https://doaj.org/article/d38f07913d0549e292ce64aaddf8922a
Autor:
Jonathan Chen, Lori Mitchell, John P. Hirdes, Jennifer Major, Christine Quinn, Selma Didic, Kaye Phillips, Micaela Jantzi
Publikováno v:
Journal of the American Medical Directors Association. 21:817-822
Objectives To evaluate the impact of a multicenter intervention to reduce potentially inappropriate antipsychotic use in Canadian nursing homes at the individual and facility levels. Design Longitudinal, population-based cohort study to evaluate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7761cd4bd2497805ab283da45f4629c0
https://doi.org/10.1016/j.jamda.2020.04.004
https://doi.org/10.1016/j.jamda.2020.04.004
Autor:
Jonathan D. Smith, Kailash Gulshan, Nima Sharifi, J. Mark Brown, Emmanuel Opoku, Jennifer Major, Hanxu Lu, Shuhui Wang Lorkowski, C. Alicia Traughber, Gregory Brubaker, Aimalie Hardaway, Yoon-Mi Chung, Chase K.A. Neumann
Publikováno v:
J Biol Chem
High-density lipoprotein (HDL) metabolism is facilitated in part by scavenger receptor class B, type 1 (SR-B1) that mediates HDL uptake into cells. Higher levels of HDL have been associated with protection in other diseases, however, its role in pros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58fa2418d971e73fce674eb77f5ddb4f
https://doi.org/10.1074/jbc.ra120.013694
https://doi.org/10.1074/jbc.ra120.013694
Autor:
Gary J. Brouhard, Scott Forth, Tatyana Bodrug, Larisa Gheber, Jawdat Al-Bassam, Jennifer Major, Steven S. Rosenfeld, Malina K. Iwanski, Himanshu Pandey, Adam G. Hendricks, Stanley Nithiananatham, Ignas Gaska, Sayaka Inagaki
The conserved kinesin-5 bipolar tetrameric motors slide apart microtubules during mitotic spindle assembly and elongation. Kinesin-5 bipolar organization originates from its conserved tetrameric helical minifilament, which position the C-terminal tai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8c244382329a52af5e364281a56394d
https://doi.org/10.1101/2021.10.12.463902
https://doi.org/10.1101/2021.10.12.463902
Autor:
Jonathan D. Smith, Jennifer Major, Aimalie Hardaway, Kailash Gulshan, Emmanuel Opoku, Gregory Brubaker, Nima Sharifi, C. Alicia Traughber, Hanxu Lu, Yoon-Mi Chung, Shuhui Wang Lorkowski, Chase K.A. Neumann, J. Mark Brown
High density lipoprotein (HDL) metabolism, in part, is facilitated by scavenger receptor class B, type 1 (SR-B1) that mediates its uptake into cells. SR-B1 is upregulated in prostate cancer tissue. Here, we report that knockout (KO) of SR-B1 via CRIS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66bddb0092f8c0c37f14e263597c08e5
https://doi.org/10.1101/2020.02.24.963454
https://doi.org/10.1101/2020.02.24.963454
Autor:
Ronald A. Milligan, Steven S. Rosenfeld, Garrett Debs, Larisa Gheber, Charles V. Sindelar, April Alfieri, Jawdat Al-Bassam, Jennifer Major, Ignas Gaska, Sayaka Inagaki, Pedro Gutierrez, Elizabeth M. Wilson-Kubalek, Stanley Nithianantham, Alex F. Thompson, Scott Forth, Richard J. McKenney, Tatyana Bodrug, Jason Stumpff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76cf8c0224bd6bc0193649d556198eb8
https://doi.org/10.7554/elife.51131.sa2
https://doi.org/10.7554/elife.51131.sa2
Autor:
Pedro Gutierrez, April Alfieri, Jason Stumpff, Alex F. Thompson, Larisa Gheber, Garrett Debs, Jawdat Al-Bassam, Scott Forth, Ignas Gaska, Tatyana Bodrug, Sayaka Inagaki, Steven S. Rosenfeld, Elizabeth M. Wilson-Kubalek, Charles V. Sindelar, Jennifer Major, Richard J. McKenney, Ronald A. Milligan, Stanley Nithianantham
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Kinesin-5 motors organize mitotic spindles by sliding apart microtubules. They are homotetramers with dimeric motor and tail domains at both ends of a bipolar minifilament. Here, we describe a regulatory mechanism involving direct binding between tai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1caba7112fd1c37d061824bd4cf3f9db
https://pubmed.ncbi.nlm.nih.gov/31958056
https://pubmed.ncbi.nlm.nih.gov/31958056