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pro vyhledávání: '"Jennifer, Landino"'
Autor:
Jennifer Landino
Publikováno v:
Molecular Biology of the Cell. 34
Midzone microtubules, which support chromosome segregation during anaphase and define the cell division plane, transition from being dynamic in early anaphase to being stable in late anaphase. The mechanism of midzone microtubule stabilization is not
Autor:
Jennifer Landino
Publikováno v:
Molecular Biology of the Cell. 34
Kidney epithelial cells operate under high mechanical stress and require biochemical responses to maintain proper morphology and function. This study investigates how the mechanosensitive channel Piezo contributes to mechanotransduction in Drosophila
Autor:
Jennifer Landino
Publikováno v:
Molecular Biology of the Cell. 33
Although the relationship between genome and cell size is well defined in developed tissues, it remains unclear when in development nuclear-cytoplasmic scaling is established. Here the authors analyzed multiple Xenopus species with varying genome and
Autor:
Jennifer Landino, Marcin Leda, Ani Michaud, Zachary T. Swider, Mariah Prom, Christine M. Field, William M. Bement, Anthony Vecchiarelli, Andrew B. Goryachev, Ann L. Miller
Publikováno v:
Biophysical Journal. 122:167a-168a
Autor:
Jennifer, Landino
Publikováno v:
Molecular biology of the cell. 33(12)
Autor:
Jennifer Landino
Publikováno v:
Molecular biology of the cell. 33(12)
Aneuploidy, a key hallmark of cancer cells, is caused by chromosome missegregation. Correct chromosome alignment in the mitotic spindle depends on the action of microtubule plus-end directed motors. However tools to induce missegregation of specific
Autor:
Zachary T. Swider, Ann L. Miller, George von Dassow, Ani Michaud, Andrew B. Goryachev, William M. Bement, Marcin Leda, Jennifer Landino
Publikováno v:
Curr Biol
Michaud, A, Swider, Z T, Landino, J, Leda, M, Miller, A L, von Dassow, G, Goryachev, A B & Bement, W M 2021, ' Cortical excitability and cell division ', Current Biology, vol. 31, no. 10, pp. PR553-R559 . https://doi.org/10.1016/j.cub.2021.02.053
Michaud, A, Swider, Z T, Landino, J, Leda, M, Miller, A L, von Dassow, G, Goryachev, A B & Bement, W M 2021, ' Cortical excitability and cell division ', Current Biology, vol. 31, no. 10, pp. PR553-R559 . https://doi.org/10.1016/j.cub.2021.02.053
As the interface between the cell and its environment, the cell cortex must be able to respond to a variety of external stimuli. This is made possible in part by cortical excitability, a behavior driven by coupled positive and negative feedback loops
Autor:
Ani Michaud, Marcin Leda, Zachary T. Swider, Songeun Kim, Jiaye He, Jennifer Landino, Jenna R. Valley, Jan Huisken, Andrew B. Goryachev, George von Dassow, William M. Bement
Publikováno v:
Michaud, A, Leda, M, Swider, Z T, Kim, S, He, J, Landino, J, Valley, J R, Huisken, J, Goryachev, A B, von Dassow, G & Bement, W M 2022, ' A versatile cortical pattern-forming circuit based on Rho, F-actin, Ect2 and RGA-3/4 ', Journal of Cell Biology, vol. 221, no. 8, e202203017 . https://doi.org/10.1083/jcb.202203017
Many cells can generate complementary traveling waves of actin filaments (F-actin) and cytoskeletal regulators. This phenomenon, termed cortical excitability, results from coupled positive and negative feedback loops of cytoskeletal regulators. The n
Autor:
Jennifer Landino
Publikováno v:
Molecular biology of the cell. 33(7)
Metaphase cell rounding is an important step during cell division; however, the cell cycle regulation of the ezrin, radixin, and moesin (ERM) proteins which drive cell rounding is not well understood. Using a small molecule screen, the authors unexpe
Autor:
Zachary T, Swider, Ani, Michaud, Marcin, Leda, Jennifer, Landino, Andrew B, Goryachev, William M, Bement
Publikováno v:
Molecular biology of the cell. 33(8)
Interest in cortical excitability-the ability of the cell cortex to generate traveling waves of protein activity-has grown considerably over the past 20 years. Attributing biological functions to cortical excitability requires an understanding of the