Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jennifer, Fiegel"'
Autor:
Mai H. Tu, Timothy M. Brenza, Margaret R. Ketterer, Morgan Timm, Benjamin M. King, Michael A. Apicella, Jennifer Fiegel
Publikováno v:
KONA Powder and Particle Journal, Vol 41, Iss 0, Pp 265-279 (2023)
Several bacterial pathogens contain membrane ligands that facilitate their binding and internalization into human tissues. In this study, lipooligosaccharides (LOS) from the respiratory pathogen non-typeable Haemophilus influenzae (NTHi) were isolate
Externí odkaz:
https://doaj.org/article/ed0617b1c04747a4947da5999904bc4d
Publikováno v:
Pharmaceutical Research. 39:2515-2527
Treating chronic wounds is a significant clinical challenge, and a topical product would be ideal for pain management. Poloxamer 407, a thermosensitive polymer, would allow an analgesic drug to be topically applied to a wound as a liquid that transit
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1214 (2020)
Chronic wounds are a significant and growing health problem, and clinical treatment is often a painful experience. A topical dosage form would be optimal to treat this pain. Poloxamer 407, a thermosensitive polymer that is a liquid at low temperature
Externí odkaz:
https://doaj.org/article/b1ed789ec0b8495082cf8cb800f8e9d4
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 496 (2020)
Naltrexone (NTX) hydrochloride is a potent opioid antagonist with significant first-pass metabolism and notable untoward effects when administered orally or intramuscularly. Microneedle (MN)-assisted transdermal delivery is an attractive alternative
Externí odkaz:
https://doaj.org/article/e6894fcacfd94174af485b065738175f
Publikováno v:
Soft Matter. 16:7823-7834
The effects of surface tension and surface viscoelastic properties on the formation of aerosol droplets generated from mucus-like viscoelastic gels (mucus mimetics) during shearing with a high velocity air stream were investigated. Mucus mimetic samp
Autor:
Benjamin M. King, Jennifer Fiegel
Publikováno v:
The AAPS Journal. 24
Autor:
Benjamin M, King, Jennifer, Fiegel
Publikováno v:
The AAPS journal. 24(1)
Zwitterionic polymers are a class of materials that have demonstrated utility as non-fouling surfaces for medical devices and drug delivery vehicles. Here, we develop a synthesis protocol to produce zwitterionic polymers as coatings for gold nanopart
Publikováno v:
Polymers, Vol 13, Iss 933, p 933 (2021)
Polymers
Volume 13
Issue 6
Polymers
Volume 13
Issue 6
Transdermal delivery of naltrexone (NTX) can be enhanced using microneedles, although micropores generated this way can reseal by 48 h in humans, which prevents further drug delivery from a formulation. Poloxamer 407 (P407) is a thermosensitive polym
Publikováno v:
Antibiotics, Vol 9, Iss 2, p 56 (2020)
Antibiotics
Antibiotics
The epidermal skin barrier protects the body from a host of daily challenges, providing protection against mechanical insults and the absorption of chemicals and xenobiotics. In addition to the physical barrier, the epidermis also presents an innate
Publikováno v:
International Journal of Pharmaceutics. 531:14-23
The purpose of this study was to formulate a dry powder for inhalation containing a combination treatment for eradication of Pseudomonas aeruginosa bacterial biofilms. Dry powders containing an antibiotic (ciprofloxacin hydrochloride, CH) and nutrien