Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jennifer, Cimons"'
Autor:
Amanda Agazio, Jennifer Cimons, Kristin M. Shotts, Kejun Guo, Mario L. Santiago, Roberta Pelanda, Raul M. Torres
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Peripheral tolerance is essential for silencing weakly autoreactive B cells that have escaped central tolerance, but it is unclear why these potentially pathogenic B cells are retained rather than being eliminated entirely. Release from peripheral to
Externí odkaz:
https://doaj.org/article/3e918bf19a4a461ea7dc86464daa4711
Autor:
Raul M. Torres, Jennifer Cimons, Mario L. Santiago, Kristin M. Shotts, Roberta Pelanda, Kejun Guo, Amanda Agazio
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Peripheral tolerance is essential for silencing weakly autoreactive B cells that have escaped central tolerance, but it is unclear why these potentially pathogenic B cells are retained rather than being eliminated entirely. Release from peripheral to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2ffcad82e3bb238eb7ef471ea1e9b7
https://pubmed.ncbi.nlm.nih.gov/32849530
https://pubmed.ncbi.nlm.nih.gov/32849530
Publikováno v:
Blood. 138:736-736
Chimeric antigen receptor (CAR) T cell therapy has emerged as a highly efficacious treatment for B-lineage acute lymphoblastic leukemias (B-ALL). However, downregulation of the CAR-targeted antigen on leukemia cells, predicted to reduce cellular avid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::733045c00e5b9daae2e8c67c39122b99
https://doi.org/10.1182/blood-2021-151729
https://doi.org/10.1182/blood-2021-151729
Publikováno v:
Blood. 138:2801-2801
Although T cells modified with a chimeric antigen receptor (CAR) are highly effective, durability of remissions may be limited by the poor persistence of adoptively transferred CAR T cells in patients. Growing evidence supports the idea that the pre-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::565414e82e4966bbb3231947a9dc7f3a
https://doi.org/10.1182/blood-2021-147011
https://doi.org/10.1182/blood-2021-147011
Autor:
Tyler, Borrman, Jennifer, Cimons, Michael, Cosiano, Michael, Purcaro, Brian G, Pierce, Brian M, Baker, Zhiping, Weng
Publikováno v:
Proteins. 85(5)
The ATLAS (Altered TCR Ligand Affinities and Structures) database (https://zlab.umassmed.edu/atlas/web/) is a manually curated repository containing the binding affinities for wild-type and mutant T cell receptors (TCRs) and their antigens, peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b1a441e77242e2ee21102d070cbfa41
https://pubmed.ncbi.nlm.nih.gov/28160322
https://pubmed.ncbi.nlm.nih.gov/28160322