Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jennifa Gosling"'
Autor:
Marilena Gallotta, Jennifa Gosling, Austin Tenn-McClellan, Serena Ranucci, Jose Gomez Romo, Frederick Cohen, Gwenn Hansen, Arthur Sands, Cristiana Guiducci, Ryan Rountree
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Marilena Gallotta, Jose Gomez Romo, Alexandra Borodovsky, Austin Tenn-McClellan, Jennifer Stokes, Jennifa Gosling, Gwenn M. Hansen, Arthur Sands, Ryan Rountree, Cristiana Guiducci
Publikováno v:
Cancer Research. 82:573-573
Adoptive cell transfer (ACT) involving autologous tumor-specific lymphocytes (TIL) has shown promising results in the treatment of advanced cancer. Poor in vitro cell expansion, inefficient T-cell migration and T cell exhaustion in the tumor microenv
Autor:
Arthur T. Sands, Alexandra Borodovsky, Chris Karim, Austin Tenn-McClellan, Jose Gomez Romo, Gwenn M. Hansen, Jennifa Gosling, Jennifer Stokes, Ryan Rountree, Cristiana Guiducci, Marilena Gallotta, Frederick Cohen
Publikováno v:
Cancer Research. 81:1595-1595
The E3 ubiquitin ligase Casitas B-lineage lymphoma b (CBL-B) is expressed in T cells where it functions as an important negative regulator of immune activation. CBL-B d attenuates T-cell activation initiated by TCR engagement in part by mediating the
Autor:
Frederick Cohen, Jennifa Gosling, Monisha Mani, Austin Tenn-McClellan, Janine Powers, Whelan Sarah Anne, Arthur T. Sands, Gwenn M. Hansen, Michael T. Lotze
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A107-A107
BackgroundAdoptive cell transfer (ACT) of TIL effects durable responses in patients with melanoma and some epithelial tumors. It is thought that poor in vitro cell expansion and inefficient T-cell migration to the tumor limits the broader application
Autor:
Austin Tenn-McClellan, Hiroko Tanaka, Joseph Juan, Christoph W. Zapf, Katherine Kurylo, Pallavur Sivakumar, Anne-Renee van der Vuurst de Vries, Ryan Rountree, Andria Christianson, Jennifer McKinnell, Ketki Dhamnaskar, Christopher Karim, Thomas Cummins, Frederick Cohen, Paul A. Barsanti, May Tan, Jilliane Bruffey, Asad M. Taherbhoy, Mario G. Cardozo, Chenbo Wang, Szerenke Kiss von Soly, Julie Sheung, Dahlia Weiss, Mark Gallop, Anjanabha Saha, Neil F. Bence, Dane Karr, Jennifa Gosling, Kathleen A. Boyle
Publikováno v:
Cancer Research. 79:2696-2696
E3 ubiquitin ligases play critical roles in directing cellular protein fate by controlling the specificity of ubiquitin conjugation to substrate proteins and targeting them for cellular relocalization or degradation by the ubiquitin proteasome system
Publikováno v:
Journal of Interferon & Cytokine Research. 24:611-620
Publikováno v:
Journal of Interferon & Cytokine Research. 24:611-620
Human cytomegalovirus (CMV) (Toledo strain) produces a potent chemokine (vCXCL-1) that specifically recognizes human (Hu)CXCR2, one of two human CXCL8 (IL8) receptors found on peripheral blood neutrophils. Thioglycollate-elicited neutrophils from BAL
Autor:
Steven L. Kunkel, Theodore J. Standiford, Nicholas W. Lukacs, Landin Boring, Cory M. Hogaboam, Borna Mehrad, Jennifa Gosling, Kate Blease, Israel F. Charo
Publikováno v:
The Journal of Immunology. 165:2603-2611
Allergic responses to Aspergillus species exacerbate asthma and cystic fibrosis. The natural defense against live Aspergillus fumigatus spores or conidia depends on the recruitment and activation of mononuclear and polymorphonuclear leukocytes, event
Autor:
Jennifa Gosling, Steven L. Kunkel, Matthew L. Steinhauser, Landin Boring, Cory M. Hogaboam, Kenneth J. Simpson, Cynthia L. Bone-Larson, Israel F. Charo, Nicholas W. Lukacs, Akihiro Matsukawa
Publikováno v:
The American Journal of Pathology. 156:1245-1252
Monocyte chemoattractant protein-1 is one of the major C-C chemokines that has been implicated in liver injury. The C-C chemokine receptor, CCR2, has been identified as the primary receptor that mediates monocyte chemoattractant protein-1 (MCP-1) res
Autor:
Roman Krzysiek, Pierre Galanaud, Jennifa Gosling, Yolande Richard, Thomas J. Schall, Arnaud Foussat, Ingrid Durand-Gasselin, Axel Balian, Aurore Coulomb-L'Hermine, Dominique Emilie
Publikováno v:
European Journal of Immunology. 30:87-97
Expression and function of the fractalkine receptor CX3CR1 by T lymphocyte subpopulations was evaluated in healthy individuals. In CD8(+) T lymphocytes, CX3CR1 was expressed by and functional in both CD45RO(-) and CD45RO(+) cells. In CD4(+) T lymphoc