Review of guidelines for the prevention and treatment of infection in patients with an absent or dysfunctional spleen: Prepared on behalf of the British Committee for Standards in Haematology by a Working Party of the Haemato‐Oncology Task Force

Autor: Imran Rafi, Shamez N Ladhani, Michael P. Lewis, Jennie Z Wimperis, Paula H. B. Bolton-Maggs, John Davies

Publikováno v: British Journal of Haematology. 155:308-317

Guidelines for the prevention and treatment of infection in patients with an absent or dysfunctional spleen were first published by the British Committee for Standards in Haematology (BCSH) in 1996 and formally reviewed in 2002. Although the guidelin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1003c283a165266f99a39102c757ef1c
https://doi.org/10.1111/j.1365-2141.2011.08843.x

Results of a trial of PET-directed therapy for early-stage Hodgkin's lymphoma

Autor: Nicholas Counsell, Sally F. Barrington, Peter Hoskin, Paul Smith, John Radford, Dominic Culligan, Alison Brownell, R. Pettengell, Peter Johnson, Andrew Lister, Jennie Z Wimperis, Andrew McMillan, Anton Kruger, Barry W. Hancock, Michael O'Doherty, Bilyana Popova, Timothy M Illidge

Publikováno v: Radford, J, Illidge, T, Counsell, N, Hancock, B, Pettengell, R, Johnson, P, Wimperis, J, Culligan, D, Popova, B, Smith, P, McMillan, A, Brownell, A, Kruger, A, Lister, A, Hoskin, P, O'Doherty, M & Barrington, S 2015, ' Results of a Trial of PET-Directed Therapy for Early-Stage Hodgkin's Lymphoma ', New England Journal of Medicine, vol. 372, no. 17, pp. 1598-1607 . https://doi.org/10.1056/NEJMoa1408648

It is unclear whether patients with early-stage Hodgkin's lymphoma and negative findings on positron-emission tomography (PET) after three cycles of chemotherapy with doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) require radiotherapy.Pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fe299ac2b0808bbc240e41fc60cc1a
https://pubmed.ncbi.nlm.nih.gov/26583613

A High Prevalence of HLA-H 845A Mutations in Hemochromatosis Patients and the Normal Population in Eastern England

Autor: Gavin Willis, Barbara A. Jennings, Emma Goodman, Jennie Z Wimperis, Ian W Fellows

Publikováno v: Blood Cells, Molecules, and Diseases. 23:288-291

ABSTRACT: We have examined normal individuals and all the patients currently being treated for hemochromatosis at the Norfolk and Norwich hospital for mutations in the HLA-H gene. We found a gene frequency in 200 normal subjects for the 845A (C282Y)

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https://doi.org/10.1006/bcmd.1997.0145

Hepatocellular carcinoma and the penetrance of HFE C282Y mutations: a cross sectional study

Autor: Vicky Bardsley, Jennie Z Wimperis, Gavin Willis, Barbara A. Jennings, Ray Lonsdale, Ian W Fellows

Publikováno v: BMC Gastroenterology
BMC Gastroenterology, Vol 5, Iss 1, p 17 (2005)

Background Although most patients with hereditary haemochromatosis have HFE C282Y mutations, the lifetime risk to HFE C282Y homozygotes of developing fatal diseases such as hepatocellular carcinoma is uncertain. We have carried out a cross-sectional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851ec0d4f4c86a541b208f2caefa3027
https://pubmed.ncbi.nlm.nih.gov/15929796

HFE mutations in the elderly

Autor: Gavin Willis, Jennie Z Wimperis, Katy Smith, Barbara A. Jennings, Ian W Fellows

Publikováno v: Blood cells, moleculesdiseases. 31(2)

Most individuals diagnosed with hereditary hemochromatosis have mutations in both copies of the HFE gene, with such mutations being common in populations of north European origin. The number of individuals currently diagnosed and treated for hemochro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17009a4fde1a749940b7cc05c86be680
https://pubmed.ncbi.nlm.nih.gov/12972032