Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jennie Strindlund"'
Publikováno v:
Toxicology. 136:1-13
Tricyclic antidepressants can, when taken in overdose, cause serious pulmonary failure such as the adult respiratory distress syndrome (ARDS). In this study we have examined the effects of some tricyclic antidepressants (amitriptyline, imipramine, no
Autor:
Dirk Weigelt, Andreas Nolting, Karin J. Sterky, Jennie Strindlund, Fernando Sehgelmeble, Daniel Sohn, Alexander Minidis, Rebecka From, Narhi Katja, Eva Nyman, Jenny Bernström, Ellen Santangelo, Karl S. A. Vallin, Christian Linde
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(17)
A series of potent antagonists of the ion channel transient receptor potential A1 (TRPA1) was developed by modifying lead structure 16 that was discovered by high-throughput screening. Based on lead compound 16 , a SAR was established, showing a narr