Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jenni Vasara"'
Autor:
Matti Mauramo, Tuulia Onali, Wafa Wahbi, Jenni Vasara, Anniina Lampinen, Elina Mauramo, Anne Kivimäki, Stefan Martens, Hely Häggman, Meeri Sutinen, Tuula Salo
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1319 (2021)
Previous studies indicate that bilberry with high amounts of phenolic compounds can inhibit carcinogenic processes of colorectal cancer in vitro and in vivo. However, no studies have focused on the effects of bilberry on oral cancer. In this study, w
Externí odkaz:
https://doaj.org/article/da8c5efa299a43f4ba737eaed617a844
Autor:
Nagy Habib, John J. Rossi, David C. Blakey, Hans E. Huber, Pal Saetrom, Chris Wood, Robert Habib, Jenni Vasara, Steve Felstead, Peter Lloyd, Pinelopi Andrikakou, Stephanie Dorman, Jon Voutila, Vikash Reebye, Sonia Fairbairn, Helen Glenny, Robert Nutbrown, David Collin, Joanna P. Nicholls, Vineet Kwatra, Sarah Hunter, James Spicer, David J. Pinato, Rohini Sharma, Madhava Pai, Duncan R.C. Spalding, T.R. Jeff Evans, Yuk Ting Ma, Daniel H. Palmer, Kai-Wen Huang, Cheng Ean Chee, Bristi Basu, Mikael H. Sodergren, Tim Meyer, Ruth Plummer, Debashis Sarker
A) CT and MRI of patient with prolonged partial response with MTL-CEBPA treatment B) IFN-gamma, NFkB and IL6 trend at days 1, 8 and 15 following treatment and C) AFP change at from baseline to 4, 8 and 16 weeks on treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ab81451fcfb34da9fcfeff4eda3c4e
https://doi.org/10.1158/1078-0432.22477086
https://doi.org/10.1158/1078-0432.22477086
Autor:
Nagy Habib, John J. Rossi, David C. Blakey, Hans E. Huber, Pal Saetrom, Chris Wood, Robert Habib, Jenni Vasara, Steve Felstead, Peter Lloyd, Pinelopi Andrikakou, Stephanie Dorman, Jon Voutila, Vikash Reebye, Sonia Fairbairn, Helen Glenny, Robert Nutbrown, David Collin, Joanna P. Nicholls, Vineet Kwatra, Sarah Hunter, James Spicer, David J. Pinato, Rohini Sharma, Madhava Pai, Duncan R.C. Spalding, T.R. Jeff Evans, Yuk Ting Ma, Daniel H. Palmer, Kai-Wen Huang, Cheng Ean Chee, Bristi Basu, Mikael H. Sodergren, Tim Meyer, Ruth Plummer, Debashis Sarker
Supplementary Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c7e811910e435bac98f627935365fd
https://doi.org/10.1158/1078-0432.22477080.v1
https://doi.org/10.1158/1078-0432.22477080.v1
Autor:
Nagy Habib, John J. Rossi, David C. Blakey, Hans E. Huber, Pal Saetrom, Chris Wood, Robert Habib, Jenni Vasara, Steve Felstead, Peter Lloyd, Pinelopi Andrikakou, Stephanie Dorman, Jon Voutila, Vikash Reebye, Sonia Fairbairn, Helen Glenny, Robert Nutbrown, David Collin, Joanna P. Nicholls, Vineet Kwatra, Sarah Hunter, James Spicer, David J. Pinato, Rohini Sharma, Madhava Pai, Duncan R.C. Spalding, T.R. Jeff Evans, Yuk Ting Ma, Daniel H. Palmer, Kai-Wen Huang, Cheng Ean Chee, Bristi Basu, Mikael H. Sodergren, Tim Meyer, Ruth Plummer, Debashis Sarker
Showing complete radiological response of lung metastases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77745179950de77a7a87e254666ef1c3
https://doi.org/10.1158/1078-0432.22477083.v1
https://doi.org/10.1158/1078-0432.22477083.v1
Autor:
Nagy Habib, John J. Rossi, David C. Blakey, Hans E. Huber, Pal Saetrom, Chris Wood, Robert Habib, Jenni Vasara, Steve Felstead, Peter Lloyd, Pinelopi Andrikakou, Stephanie Dorman, Jon Voutila, Vikash Reebye, Sonia Fairbairn, Helen Glenny, Robert Nutbrown, David Collin, Joanna P. Nicholls, Vineet Kwatra, Sarah Hunter, James Spicer, David J. Pinato, Rohini Sharma, Madhava Pai, Duncan R.C. Spalding, T.R. Jeff Evans, Yuk Ting Ma, Daniel H. Palmer, Kai-Wen Huang, Cheng Ean Chee, Bristi Basu, Mikael H. Sodergren, Tim Meyer, Ruth Plummer, Debashis Sarker
Dose escalation flow chart. DLT - dose limiting toxicity, MTD - maximum tolerated dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f45e2fcc07497a12f923f330fe0e40d
https://doi.org/10.1158/1078-0432.22477095.v1
https://doi.org/10.1158/1078-0432.22477095.v1
Autor:
Nagy Habib, John J. Rossi, David C. Blakey, Hans E. Huber, Pal Saetrom, Chris Wood, Robert Habib, Jenni Vasara, Steve Felstead, Peter Lloyd, Pinelopi Andrikakou, Stephanie Dorman, Jon Voutila, Vikash Reebye, Sonia Fairbairn, Helen Glenny, Robert Nutbrown, David Collin, Joanna P. Nicholls, Vineet Kwatra, Sarah Hunter, James Spicer, David J. Pinato, Rohini Sharma, Madhava Pai, Duncan R.C. Spalding, T.R. Jeff Evans, Yuk Ting Ma, Daniel H. Palmer, Kai-Wen Huang, Cheng Ean Chee, Bristi Basu, Mikael H. Sodergren, Tim Meyer, Ruth Plummer, Debashis Sarker
Trial Protocol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904983ab44a60b491e369e12d54f27a4
https://doi.org/10.1158/1078-0432.22477098
https://doi.org/10.1158/1078-0432.22477098
Autor:
Nagy Habib, John J. Rossi, David C. Blakey, Hans E. Huber, Pal Saetrom, Chris Wood, Robert Habib, Jenni Vasara, Steve Felstead, Peter Lloyd, Pinelopi Andrikakou, Stephanie Dorman, Jon Voutila, Vikash Reebye, Sonia Fairbairn, Helen Glenny, Robert Nutbrown, David Collin, Joanna P. Nicholls, Vineet Kwatra, Sarah Hunter, James Spicer, David J. Pinato, Rohini Sharma, Madhava Pai, Duncan R.C. Spalding, T.R. Jeff Evans, Yuk Ting Ma, Daniel H. Palmer, Kai-Wen Huang, Cheng Ean Chee, Bristi Basu, Mikael H. Sodergren, Tim Meyer, Ruth Plummer, Debashis Sarker
Supplementary Table 1 CEBPA-51 PK parameters Supplementary Table 2 RECIST 1.1 response observed overall and per cohorts in HCC patients at cut-off (12 Sep 2018) presented as n (%)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce35daac7a415cf4cb7dfd189462b42
https://doi.org/10.1158/1078-0432.22477077.v1
https://doi.org/10.1158/1078-0432.22477077.v1
Autor:
Nagy Habib, John J. Rossi, David C. Blakey, Hans E. Huber, Pal Saetrom, Chris Wood, Robert Habib, Jenni Vasara, Steve Felstead, Peter Lloyd, Pinelopi Andrikakou, Stephanie Dorman, Jon Voutila, Vikash Reebye, Sonia Fairbairn, Helen Glenny, Robert Nutbrown, David Collin, Joanna P. Nicholls, Vineet Kwatra, Sarah Hunter, James Spicer, David J. Pinato, Rohini Sharma, Madhava Pai, Duncan R.C. Spalding, T.R. Jeff Evans, Yuk Ting Ma, Daniel H. Palmer, Kai-Wen Huang, Cheng Ean Chee, Bristi Basu, Mikael H. Sodergren, Tim Meyer, Ruth Plummer, Debashis Sarker
Purpose:Transcription factor C/EBP-α (CCAAT/enhancer-binding protein alpha) acts as a master regulator of hepatic and myeloid functions and multiple oncogenic processes. MTL-CEBPA is a first-in-class small activating RNA oligonucleotide drug that up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655dfedd00417d62da05144f7bcb5f4f
https://doi.org/10.1158/1078-0432.c.6529569
https://doi.org/10.1158/1078-0432.c.6529569
Autor:
Nagy Habib, John J. Rossi, David C. Blakey, Hans E. Huber, Pal Saetrom, Chris Wood, Robert Habib, Jenni Vasara, Steve Felstead, Peter Lloyd, Pinelopi Andrikakou, Stephanie Dorman, Jon Voutila, Vikash Reebye, Sonia Fairbairn, Helen Glenny, Robert Nutbrown, David Collin, Joanna P. Nicholls, Vineet Kwatra, Sarah Hunter, James Spicer, David J. Pinato, Rohini Sharma, Madhava Pai, Duncan R.C. Spalding, T.R. Jeff Evans, Yuk Ting Ma, Daniel H. Palmer, Kai-Wen Huang, Cheng Ean Chee, Bristi Basu, Mikael H. Sodergren, Tim Meyer, Ruth Plummer, Debashis Sarker
Longitudinal changes in WBC mRNA expression of CEBPA, adenosine, PD-1 & CXCR4 at screening, day2, 8 and 15 of a single patient treated in the 130mg/m2 cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1792a6da256cefb45e0af3543b920792
https://doi.org/10.1158/1078-0432.22477089.v1
https://doi.org/10.1158/1078-0432.22477089.v1
Autor:
Nagy Habib, John J. Rossi, David C. Blakey, Hans E. Huber, Pal Saetrom, Chris Wood, Robert Habib, Jenni Vasara, Steve Felstead, Peter Lloyd, Pinelopi Andrikakou, Stephanie Dorman, Jon Voutila, Vikash Reebye, Sonia Fairbairn, Helen Glenny, Robert Nutbrown, David Collin, Joanna P. Nicholls, Vineet Kwatra, Sarah Hunter, James Spicer, David J. Pinato, Rohini Sharma, Madhava Pai, Duncan R.C. Spalding, T.R. Jeff Evans, Yuk Ting Ma, Daniel H. Palmer, Kai-Wen Huang, Cheng Ean Chee, Bristi Basu, Mikael H. Sodergren, Tim Meyer, Ruth Plummer, Debashis Sarker
qPCR of CEBPA mRNA levels at days 2, 8 and 15 following treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5169ba980674ca49d979868e07c38920
https://doi.org/10.1158/1078-0432.22477092.v1
https://doi.org/10.1158/1078-0432.22477092.v1