Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jenni Kyyriäinen"'
Autor:
Jenni Kyyriäinen, Natallie Kajevu, Ivette Bañuelos, Leonardo Lara, Anssi Lipponen, Silvia Balosso, Elina Hämäläinen, Shalini Das Gupta, Noora Puhakka, Teemu Natunen, Teresa Ravizza, Annamaria Vezzani, Mikko Hiltunen, Asla Pitkänen
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10555 (2021)
We assessed the effect of antioxidant therapy using the Food and Drug Administration-approved respiratory drug N-acetylcysteine (NAC) or sulforaphane (SFN) as monotherapies or duotherapy in vitro in neuron-BV2 microglial co-cultures and validated the
Externí odkaz:
https://doaj.org/article/b998370c5ed947969d9f9c88922b1f47
Autor:
Asla Pitkänen, Noora Huusko, Xavier Ekolle Ndode-Ekane, Jenni Kyyriäinen, Anssi Lipponen, Anu Lipsanen, Alejandra Sierra, Tamuna Bolkvadze
Publikováno v:
Neurobiology of Disease, Vol 72, Iss , Pp 224-232 (2014)
Disease modification of epilepsy refers to the alleviation of epileptogenesis or comorbidities after genetic or acquired epileptogenic brain insults. There are currently 30 proof-of-concept experimental pharmacologic studies that have demonstrated so
Externí odkaz:
https://doaj.org/article/8f4ecbfa7d1043cf95c4ee94b3bed39a
Autor:
David J. Poulsen, Jenni Kyyriäinen, Kaitlynn Donahue, Kathryn Toffolo, Ferdinand Schweser, Austin Poulsen, Asla Pitkänen, Benett Levy, Marilena Preda
Publikováno v:
Neuroimage
A key event in the pathophysiology of traumatic brain injury (TBI) is the influx of substantial amounts of Ca2+ into neurons, particularly in the thalamus. Detection of this calcium influx in vivo would provide a window into the biochemical mechanism
Autor:
Xavier Ekolle Ndode-Ekane, Heikki Tanila, Anssi Lipponen, Laura Oliva Pérez, Jenni Kyyriäinen, Asla Pitkänen, Hennariikka Koivisto, Tamuna Bolkvadze
Publikováno v:
Epilepsy Research. 151:67-74
Extracellular proteolysis initiated by the binding of urokinase-type plasminogen activator (uPA) to its receptor (uPAR) regulates the development of inhibitory neuronal circuits in the cerebral cortex and tissue remodeling after epileptogenic brain i
Publikováno v:
Inflammation and Epilepsy: New Vistas ISBN: 9783030674021
Post-traumatic epilepsy (PTE) is one of the clinical outcomes in about 16% of patients with traumatic brain injury (TBI). Patients develop PTE after several months to years following the initial brain injury. Over the years, there have been an increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baedf8ca9081c7492ca65352d548b8f3
https://doi.org/10.1007/978-3-030-67403-8_10
https://doi.org/10.1007/978-3-030-67403-8_10
Autor:
Robert Ciszek, Natallie Kajevu, Xavier Ekolle Ndode-Ekane, Jenni Kyyriäinen, Shalini Das Gupta, Mette Heiskanen, Tomi Paananen, Asla Pitkänen, Leonardo Lara-Valderrábano, Niina Lapinlampi, Niina Vuokila, Pedro Andrade, Noora Puhakka, Ivette Bañuelos-Cabrera
Publikováno v:
Epilepsybehavior : EB. 121
A biomarker is a characteristic that can be objectively measured as an indicator of normal biologic processes, pathogenic processes, or responses to an exposure or intervention, including therapeutic interventions. Biomarker modalities include molecu
Publikováno v:
Glia. 65:322-341
Platelet-derived growth factor receptor β (PDGFRβ) is upregulated after brain injury and its depletion results in the blood–brain barrier (BBB) damage. We investigated the time-window and localization of PDGFRβ expression in mice with intrahippo
Publikováno v:
Neuroscience Letters. 729:134935
Binding of urokinase-type plasminogen activator receptor (uPAR) to its ligand uPA or to its plasma membrane partner, platelet-derived growth factor receptor β (PDGFRβ), promotes neuroprotection, cell proliferation, and angiogenesis. Following injur
According to the World Health Organization, 50 million people worldwide have epilepsy. Traumatic brain injury (TBI) is estimated to cause 10%–20% of all of symptomatic epilepsies, and 5% of all epilepsies. Over the past 15 years, several laboratori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57d2580e0ab809bcb63b98ae044def7c
https://doi.org/10.1016/b978-0-12-804066-9.00046-8
https://doi.org/10.1016/b978-0-12-804066-9.00046-8
Publikováno v:
Glia. 65(2)
Platelet-derived growth factor receptor β (PDGFRβ) is upregulated after brain injury and its depletion results in the blood-brain barrier (BBB) damage. We investigated the time-window and localization of PDGFRβ expression in mice with intrahippoca