Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jenni Karttunen"'
Autor:
Jenni Karttunen, Lajos Kalmar, Andrew Grant, Jun Ying, Sarah E. Stewart, Xiaonan Wang, Fiona Karet Frankl, Tim Williams
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Current diagnostic methods for canine urothelial carcinoma (UC) are technically challenging or can lack specificity, hence there is a need for novel biomarkers of UC. To this end, we analysed the microRNA (miRNA) cargo of extracellular vesic
Externí odkaz:
https://doaj.org/article/408c8c855f354cefac0f325e0b50062d
Autor:
Petra Kangas, Tuula A. Nyman, Liisa Metsähonkala, Cameron Burns, Robert Tempest, Tim Williams, Jenni Karttunen, Tarja S. Jokinen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The proteomic profile of extracellular vesicles (EVs) from cerebrospinal fluid (CSF) can reveal novel biomarkers for diseases of the brain. Here, we validate an ultrafiltration combined with size-exclusion chromatography (UF-SEC) method for
Externí odkaz:
https://doaj.org/article/60b47c88faa341af9c79fe7a2783cf0a
Autor:
Jenni Karttunen, Mette Heiskanen, Tiina Joki, Anu Hyysalo, Vicente Navarro-Ferrandis, Susanna Miettinen, Susanna Narkilahti, Asla Pitkänen
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 4, Pp 151270- (2022)
Background: Extracellular vesicles (EVs) secreted by neuronal cells in vitro have promising therapeutic potential for brain diseases. Optimization of cell culture conditions and methodologies for high-yield isolation of EVs for preclinical and clinic
Externí odkaz:
https://doaj.org/article/e8e6d12614ea463580a691e3ae3548f2
Autor:
Nina Höglund, Ninna Koho, Heini Rossi, Jenni Karttunen, Anne-Mari Mustonen, Petteri Nieminen, Kirsi Rilla, Sanna Oikari, Anna Mykkänen
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Extracellular vesicles (EVs) are membrane-bound particles that engage in inflammatory reactions by mediating cell–cell interactions. Previously, EVs have been isolated from the bronchoalveolar lavage fluid (BALF) of humans and rodents. The aim of t
Externí odkaz:
https://doaj.org/article/862bd0a774c249bfb0bcd26771ea3d55
Autor:
Jenni Karttunen, Mette Heiskanen, Vicente Navarro-Ferrandis, Shalini Das Gupta, Anssi Lipponen, Noora Puhakka, Kirsi Rilla, Arto Koistinen, Asla Pitkänen
Publikováno v:
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
The microRNA (miRNA) cargo contained in plasma extracellular vesicles (EVs) offers a relatively little explored source of biomarkers for brain diseases that can be obtained noninvasively. Methods to isolate EVs from plasma, however, are still being d
Externí odkaz:
https://doaj.org/article/714647fa127c45f289b2991561f1709d
Autor:
Petra Kangas, Tuula A. Nyman, Liisa Metsähonkala, Cameron Burns, Robert Tempest, Tim Williams, Jenni Karttunen, Tarja S. Jokinen
The proteomic profile of extracellular vesicles (EVs) from cerebrospinal fluid (CSF) can reveal novel biomarkers for diseases of the brain. Here, we validate an ultrafiltration combined with size-exclusion chromatography (UF-SEC) method for isolation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b544d9e1280aa224c908397da9d5e98a
https://doi.org/10.1101/2022.09.27.508990
https://doi.org/10.1101/2022.09.27.508990
Autor:
Victoria Neale, Jenni Karttunen, Fiona Karet Frankl, Lajos Kalmar, Andrew Grant, Tim Williams
Publikováno v:
BSAVA Congress Proceedings 2022 ISBN: 9781913859114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d4d38fe49ef74189e685070f585415f
https://doi.org/10.22233/9781913859114.38.14
https://doi.org/10.22233/9781913859114.38.14
Autor:
Jenni Karttunen, Sarah E. Stewart, Tim Williams, Andrew J. Grant, Fiona E. Karet Frankl, Lajos Kalmar
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4881, p 4881 (2021)
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4881, p 4881 (2021)
Urinary extracellular vesicles (EVs) and their RNA cargo are a novel source of biomarkers for various diseases. We aimed to identify the optimal method for isolating small (<
200 nm) EVs from human urine prior to small RNA analysis. EVs from f
200 nm) EVs from human urine prior to small RNA analysis. EVs from f
Autor:
Asla Pitkänen, Leonardo Lara-Valderrábano, Jenni Karttunen, Xavier Ekolle Ndode-Ekane, Mehwish Anwer, Noora Puhakka
Publikováno v:
Journal of neurotrauma. 37(7)
Traumatic brain injury (TBI) causes damage to the hypothalamo-hypophyseal axis, leading to endocrine dysregulation in up to 40% of TBI patients. Hence, there is an urgent need to identify non-invasive biomarkers for TBI-associated hypothalamo-hypophy
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1259 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1259 (2019)
Extracellular vesicles (EVs) are small vesicles involved in intercellular communication. Data is emerging that EVs and their cargo have potential as diagnostic biomarkers and treatments for brain diseases, including traumatic brain injury and epileps