Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jenni K Durieux"'
Autor:
Yang Xiao, Kristi Elkins, Jenni K Durieux, Leslie Lee, Jason Oeh, Lulu X Yang, Xiaorong Liang, Chris DelNagro, Jarrod Tremayne, Mandy Kwong, Bianca M Liederer, Peter K Jackson, Lisa D Belmont, Deepak Sampath, Thomas O'Brien
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 10, Pp 1151-1160 (2013)
Nicotinamide adenine dinucleotide (NAD) is a critical metabolite that is required for a range of cellular reactions. A key enzyme in the NAD salvage pathway is nicotinamide phosphoribosyl transferase (NAMPT), and here, we describe GNE-618, an NAMPT i
Externí odkaz:
https://doaj.org/article/465978c254fd40a9b156667dad2f834b
Autor:
Daniel J Anderson, Jenni K Durieux, Kyung Song, Ryan Alvarado, Peter K Jackson, Georgia Hatzivassiliou, Mary J C Ludlam
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22607 (2011)
Oncogenic mutations in the mitogen activated protein kinase (MAPK) pathway are prevalent in human tumors, making this pathway a target of drug development efforts. Recently, ATP-competitive Raf inhibitors were shown to cause MAPK pathway activation v
Externí odkaz:
https://doaj.org/article/089136d7dcfd450691807e2b917fa566