Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Jenni Harvey"'
Autor:
Jenni Harvey
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7352 (2024)
Accumulation of hyper-phosphorylated tau and amyloid beta (Aβ) are key pathological hallmarks of Alzheimer’s disease (AD). Increasing evidence indicates that in the early pre-clinical stages of AD, phosphorylation and build-up of tau drives impair
Externí odkaz:
https://doaj.org/article/2bd2d31e92af4a5e9aec0ca6b4c244af
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-18 (2023)
Abstract It is well documented that 17β estradiol (E2) regulates excitatory synaptic transmission at hippocampal Shaffer-collateral (SC)-CA1 synapses, via activation of the classical estrogen receptors (ERα and ERβ). Hippocampal CA1 pyramidal neur
Externí odkaz:
https://doaj.org/article/e894cac162b8412d947a1109d8930ad2
Autor:
Jenni Harvey
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
It is well documented that the endocrine hormone, leptin controls energy homeostasis by providing key signals to specific hypothalamic nuclei. However, our knowledge of leptin’s central actions has advanced considerably over the last 20 years, with
Externí odkaz:
https://doaj.org/article/b5040f24fbde43c7bb4eabba6983086a
Autor:
James R. Foster, Shohta Ueno, Mao Xiang Chen, Jenni Harvey, Simon J. Dowell, Andrew J. Irving, Andrew J. Brown
Publikováno v:
Pharmacology Research & Perspectives, Vol 7, Iss 6, Pp n/a-n/a (2019)
Abstract The G‐protein‐coupled receptor GPR132, also known as G2A, is activated by 9‐hydroxyoctadecadienoic acid (9‐HODE) and other oxidized fatty acids. Other suggested GPR132 agonists including lysophosphatidylcholine (LPC) have not been re
Externí odkaz:
https://doaj.org/article/7b061eaa8d9a4cbf833e82d94e845177
Autor:
Kirsty Hamilton, Jenni Harvey
Publikováno v:
Pharmaceuticals, Vol 14, Iss 1, p 52 (2021)
It is widely accepted that the endocrine hormone leptin controls food intake and energy homeostasis via activation of leptin receptors expressed on hypothalamic arcuate neurons. The hippocampal formation also displays raised levels of leptin receptor
Externí odkaz:
https://doaj.org/article/3d7de7ffd6cc4e788a1fc6772e06a3b9
Autor:
Gemma McGregor, Jenni Harvey
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
The role of the endocrine hormone leptin in controlling energy homeostasis in the hypothalamus are well documented. However the CNS targets for leptin are not restricted to the hypothalamus as a high density of leptin receptors are also expressed in
Externí odkaz:
https://doaj.org/article/c22aa3e4efaa4c3c937e0fab26c4acb3
Autor:
Dayne Beccano-Kelly, Jenni Harvey
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2012 (2012)
It is well established that the hormone leptin circulates in the plasma in amounts proportional to body fat content and it regulates food intake and body weight via its actions in the hypothalamus. However, numerous studies have shown that leptin rec
Externí odkaz:
https://doaj.org/article/7d6a8aeda56b4b16876b3915e0437aee
Autor:
Gayle Doherty, Alison Holiday, Yasaman Malekizadeh, Cosmin Manolescu, Stephen Duncan, Iona Flewitt, Kirsty Hamilton, Beth MacLeod, James A. Ainge, Jenni Harvey
Funding: This work was supported by a Medical Research Scotland vacation award for BM, Sulsa Dementia grants to JH & GHD. Key pathological features of Alzheimer’s disease (AD) include build-up of amyloid β (Aβ), which promotes synaptic abnormalit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a0d04758025e099e868de51b2054a5
https://hdl.handle.net/10023/26606
https://hdl.handle.net/10023/26606
Autor:
Jenni, Harvey
Publikováno v:
Vitamins and hormones. 118
Increasing evidence indicates that the metabolic hormone, leptin markedly influences the functioning of the hippocampus. In particular, exposure to leptin results in persistent changes in synaptic efficacy at both temporoammonic (TA) and Schaffer Col
Autor:
Jenni Harvey
Publikováno v:
Vitamins and Hormones ISBN: 9780323992213
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f662b136b7f65a5b9a5364bcae8c46f5
https://doi.org/10.1016/bs.vh.2021.12.002
https://doi.org/10.1016/bs.vh.2021.12.002