Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jenni, Risler"'
Autor:
Lynn K. Barrett, Wen Dong, Kimberly Loesch, Sandhya Subramanian, Wesley C. Van Voorhis, Dwight Baker, Justin K. Craig, Jenni Risler, Ram Samudrala
Publikováno v:
J Biomol Screen
New and improved drugs against tuberculosis are urgently needed as multi-drug resistant forms of the disease become more prevalent. Mycobacterium tuberculosis cytidylate kinase is an attractive target for screening due to its essentiality and differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c9e25637532c1aa33ce8209a136fc9
https://europepmc.org/articles/PMC8565994/
https://europepmc.org/articles/PMC8565994/
Autor:
Nicolle B. Krusberski, Carly A. Holstein, Lee Adams, Ryan J. Austin, Deborah K. Chang, Jenni Risler, Jonathan H. Wang, Daniel Martin, Lik Wee Lee
Publikováno v:
PROTEOMICS. 12:2078-2083
Expression of isotopically labeled peptide standards as artificial concatamers (QconCATs) allows for the multiplex quantification of proteins in unlabeled samples by mass spectrometry. We have developed a generalizable QconCAT design strategy, which
Autor:
Jenni Risler, Daniel Martin, Jimmy K. Eng, Ruedi Aebersold, Luis Mendoza, David Shteynberg, Natalie Tasman, Lik Wee Lee, Carly A. Sherwood, Henry H N Lam, Amelia Peterson, Ashley Eastham, Eric W. Deutsch
Publikováno v:
Journal of Proteome Research. 8:4396-4405
Multiple reaction monitoring mass spectrometry (MRM-MS) is a targeted analysis method that has been increasingly viewed as an avenue to explore proteomes with unprecedented sensitivity and throughput. We have developed a software tool, called MaRiMba
Autor:
Jenni Risler, Jacob A. Herman, James M. Olson, Chad M. Toledo, Jennifer G. DeLuca, Julio Vazquez, Do-Hyun Nam, Christopher G. Hubert, Jeffery J. Delrow, Philip Corrin, Jeongwu Lee, Jun Zhu, Steven M. Pollard, Bin Zhang, Kyobi Skutt-Kakaria, Yu Ding, Ryan Basom, Patrick J. Paddison
Publikováno v:
Ding, Y, Hubert, C G, Herman, J, Corrin, P, Toledo, C M, Skutt-Kakaria, K, Vazquez, J, Basom, R, Zhang, B, Risler, J K, Pollard, S M, Nam, D-H, Delrow, J J, Zhu, J, Lee, J, DeLuca, J, Olson, J M & Paddison, P J 2013, ' Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells ', Cancer Discovery, vol. 3, no. 2, pp. 198-211 . https://doi.org/10.1158/2159-8290.CD-12-0353
To identify new candidate therapeutic targets for glioblastoma multiforme, we combined functional genetics and glioblastoma network modeling to identify kinases required for the growth of patient-derived brain tumor–initiating cells (BTIC) but that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07deb1428deadb1e8afe8e6797905c9e
https://www.pure.ed.ac.uk/ws/files/12908048/Cancer_Specific_requirement_for_BUB1B_BUBR1_in_human_brain_tumor_isolates_and_genetically_transformed_cell.pdf
https://www.pure.ed.ac.uk/ws/files/12908048/Cancer_Specific_requirement_for_BUB1B_BUBR1_in_human_brain_tumor_isolates_and_genetically_transformed_cell.pdf
Autor:
Ryan J, Austin, Deborah K, Chang, Carly A, Holstein, Lik W, Lee, Jenni, Risler, Jonathan H, Wang, Lee, Adams, Nicolle B, Krusberski, Daniel B, Martin
Publikováno v:
Proteomics. 12(13)
Expression of isotopically labeled peptide standards as artificial concatamers (QconCATs) allows for the multiplex quantification of proteins in unlabeled samples by mass spectrometry. We have developed a generalizable QconCAT design strategy, which
Multiple reaction monitoring mass spectrometry (MRM-MS) is a technique for high-sensitivity targeted analysis. In proteomics, MRM-MS can be used to monitor and quantify a peptide based on the production of expected fragment peaks from the selected pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37393bf97fab466c819d79ae8158fa71
https://europepmc.org/articles/PMC2802215/
https://europepmc.org/articles/PMC2802215/
Autor:
Jayson A. Falkner, Hamid Mirzaei, Ashley Eastham, Carly A. Sherwood, Lik Wee Lee, Jenni Risler, Daniel Martin
Multiple reaction monitoring (MRM) is a highly sensitive method of targeted mass spectrometry (MS) that can be used to selectively detect and quantify peptides based on the screening of specified precursor peptide-to-fragment ion transitions. MRM-MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7162046b4b49bf61b863a5a8a0b34d
https://europepmc.org/articles/PMC2811718/
https://europepmc.org/articles/PMC2811718/
Autor:
William Pryse-Phillips, Y. Paul Goldberg, Christèle Platon, Robin Sherrington, Jay Thompson, H. Banfield Younghusband, Terry D Pape, Xandra O. Breakefield, Marie-Pierre Dubé, Owen Dadivas, Sébastien Meilleur, Mark E. Samuels, Chris Radomski, Marcia L.E. MacDonald, Gudarz Davar, Simon N. Pimstone, Guy A. Rouleau, Julie MacFarlane, Ronald G. Lafrenière, Ana-Maria Guerra-Escobio, Ryan R. Brinkman, Bernard Brais, Jenni Risler, Michael R. Hayden, Mary O’Driscoll, Roger C. Green
Hereditary sensory and autonomic neuropathy (HSAN) type II is an autosomal recessive disorder characterized by impairment of pain, temperature, and touch sensation owing to reduction or absence of peripheral sensory neurons. We identified two large p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184873b2cee709895938598cf17d8069
https://europepmc.org/articles/PMC1181970/
https://europepmc.org/articles/PMC1181970/
Autor:
Patrick Franchini, Jay Thompson, Ryan Babakaiff, Y. Paul Goldberg, Gillian Lockitch, Marie-Pierre Dubé, Elizabeta Nemeth, Michael R. Hayden, Jenni Risler, C Radomski, Lisa Andres, Marcia L.E. MacDonald, George Papanikolaou, Catherine Zaborowska, Terry D Pape, Mark E. Samuels, Erwin H. Ludwig, Marianna Politou, Julie MacFarlane, John Christakis, Pierre Brissot, Owen Davidas, Tomas Ganz, Nikos Sakellaropoulos
Publikováno v:
Nature genetics. 36(1)
Juvenile hemochromatosis is an early-onset autosomal recessive disorder of iron overload resulting in cardiomyopathy, diabetes and hypogonadism that presents in the teens and early 20s (refs. 1,2). Juvenile hemochromatosis has previously been linked
Autor:
Carly A. Sherwood, Ashley Eastham, Lik Wee Lee, Amelia Peterson, Jimmy K. Eng, David Shteynberg, Luis Mendoza, Eric W. Deutsch, Jenni Risler, Natalie Tasman, Ruedi Aebersold, Henry Lam, Daniel B. Martin
Publikováno v:
Journal of Proteome Research; Oct2009, Vol. 8 Issue 10, p4396-4405, 10p