Výsledky vyhledávání - "Jennae N. Shelby"

Tacrolimus induces fibroblast-to-myofibroblast transition via a TGF-β-dependent mechanism to contribute to renal fibrosis

Autor: Adaku C. Ume, Tara Y. Wenegieme, Jennae N. Shelby, Chiagozie D. B. Paul-Onyia, Aston M. J. Waite, John K. Kamau, Danielle N. Adams, Keiichiro Susuki, Eric S. Bennett, Hongmei Ren, Clintoria R. Williams

Publikováno v: American Journal of Physiology-Renal Physiology. 324:F433-F445

Renal fibrosis, a detrimental feature of irreversible kidney damage, remains a sinister consequence of long-term calcineurin inhibitor (CNI) immunosuppressive therapy. Our study not only incorporates renal fibroblasts into the growing list of cell ty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab8f9fd164483bed39acbd8ab6f2aae8
https://doi.org/10.1152/ajprenal.00226.2022

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The Type 2 Diabetes Factor Methylglyoxal Mediates Axon Initial Segment Shortening and Alters Neuronal Function at the Cellular and Network Levels

Autor: Ryan B. Griggs, John A. Miller, Josef K. Steinbrunner, Leonid M. Yermakov, Carlos Gonzalez-Islas, Keiichiro Susuki, Peter Wenner, Jennae N. Shelby, Jeneane M. Jaber, Duc V. M. Nguyen

Publikováno v: eNeuro

Recent evidence suggests that alteration of axon initial segment (AIS) geometry (i.e., length or location along the axon) contributes to CNS dysfunction in neurological diseases. For example, AIS length is shorter in the prefrontal cortex of type 2 d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cf6c39294e79a1e607b2158743b4ac
http://europepmc.org/articles/PMC8496204

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The type 2 diabetes factor methylglyoxal mediates axon initial segment shortening and neuronal network activity changes

Autor: Jennae N. Shelby, Peter Wenner, Miller Ja, Duc V. M. Nguyen, Jaber Jm, Leonid M. Yermakov, Ryan B. Griggs, Josef K. Steinbrunner, Keiichiro Susuki, Carlos Gonzalez-Islas

Recent evidence suggests that alteration of axon initial segment (AIS) geometry (i.e., length or position along the axon) contributes to CNS dysfunction in neurological diseases. For example, AIS length is shorter in the prefrontal cortex of type 2 d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85ba24806ac10855f1586759319c00bd
https://doi.org/10.1101/2021.05.10.443439

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