Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Jenna R. Murdoch"'
1
The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice
Autor: Thore Thiesler, Alessandro Lugli, Lukas F. Mager, Viktor H. Koelzer, Inti Zlobec, Tobias Junt, Gieri Cathomas, Marie-Hélène Wasmer, Holger Moch, Jenna R. Murdoch, Giulia Ruzzante, Achim Weber, Stefanie Joller, Kirsten D. Mertz, Philippe Krebs, Thomas Brümmendorf, Vera Genitsch
Publikováno v: OncoImmunology
Mertz, Kirsten D; Mager, Lukas F.; Wasmer, Marie-Hélène; Thiesler, Thore; Kölzer, Viktor H.; Ruzzante, Giulia; Joller, Stefanie; Murdoch, Jenna R; Brümmendorf, Thomas; Genitsch Gratwohl, Vera; Lugli, Alessandro; Cathomas, Gieri; Moch, Holger; Weber, Achim; Zlobec, Inti; Junt, Tobias; Krebs, Philippe (2016). The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice. Oncoimmunology, 5(1), e1062966. Landes Bioscience 10.1080/2162402X.2015.1062966
Oncoimmunology
Colorectal cancer (CRC) develops through a multistep process and is modulated by inflammation. However, the inflammatory pathways that support intestinal tumors at different stages remain incompletely understood. Interleukin (IL)-33 signaling plays a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a6a9902d6e72acedf968d5930b7020
Zobrazit plný text záznamu
2
Chronic inflammation and asthma
Autor: Clare M. Lloyd, Jenna R. Murdoch
Publikováno v: Mutation Research
Allergic asthma is a complex and chronic inflammatory disorder which is associated with airway hyper-responsiveness and tissue remodelling of the airway structure. Although originally thought to be a Th2-driven inflammatory response to inhaled innocu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9f766eb94ffbdaf5d82371c47d8086
https://doi.org/10.1016/j.mrfmmm.2009.09.005
Zobrazit plný text záznamu
3
Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice
Autor: Kirsten D. Mertz, Laurent Peyrin-Biroulet, Mamdouh A.K. Sedhom, Lea Brault, Bernhard Ryffel, Padraic G. Fallon, Jean-Philippe Girard, Emma Lefrançais, M. Pichery, Mathias Chamaillard, Valérie Quesniaux, Nathalie Ortega, Tobias Junt, Sylvain Normand, Gieri Cathomas, Devika Sanmugalingam, Benoît Foligné, Jenna R. Murdoch, Teddy Grandjean
Publikováno v: Gut
Gut, BMJ Publishing Group, 2013, 62 (12), pp.1714-1723. ⟨10.1136/gutjnl-2011-301785⟩
Gut, 2013, 62 (12), pp.1714-1723. ⟨10.1136/gutjnl-2011-301785⟩
International audience; Objective Inflammatory bowel diseases (IBD) have been intrinsically linked to a deregulated cytokine network, but novel therapeutic principles are urgently needed. Here we identify the interleukin (IL)-33 and its receptor ST2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa690605ba279161fa24c1615ba37131
https://hal.univ-lorraine.fr/hal-01706845
Zobrazit plný text záznamu
4
Editorial: peer across the barrier--new live transmissions from the intestinal mucosa
Autor: Jenna R. Murdoch, Tobias Junt
Publikováno v: Journal of leukocyte biology. 92(3)
Intact vascular perfusion done while intravitally visualizing the intestine: mucosal DCs and T cells display activity similar to that found in secondary lymphoid organs.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e27c3978da8bc682b86f1437ccb8ca
https://pubmed.ncbi.nlm.nih.gov/22457365
Zobrazit plný text záznamu
5
Tolerizing allergic responses in the lung
Autor: Clare M. Lloyd, Jenna R. Murdoch
Publikováno v: Mucosal immunology. 3(4)
The absolute requirement of the pulmonary immune system is to limit the inflammatory consequences of inhaled infectious agents while maintaining tolerance to harmless aeroallergens. This tolerance is maintained by a complex network of cells and molec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929b7a371bb3bee8888081d8f7198071
https://pubmed.ncbi.nlm.nih.gov/20505664
Zobrazit plný text záznamu
8
Resolution of allergic airway inflammation and airway hyperreactivity is mediated by IL-17-producing {gamma}{delta}T cells
Autor: Clare M. Lloyd, Jenna R. Murdoch
Publikováno v: American journal of respiratory and critical care medicine. 182(4)
Rationale: γδT lymphocytes are enriched within the epithelial microenvironment, where they are thought to maintain homeostasis and limit immunopathology. γδT cells are postulated to exert a regulatory influence during acute allergic airway diseas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2474e5fc019e915d96d704ddc89da7af
https://pubmed.ncbi.nlm.nih.gov/20413629
Zobrazit plný text záznamu
9
Inhaled house dust mite induces pulmonary T helper 2 cytokine production
Autor: Sara A. Mathie, Clare M. Lloyd, Jenna R. Murdoch, Christopher P. Thomas, Benjamin Causton, Lisa G. Gregory, F. M. Priest, Valerie B. O'Donnell, Diana Quint
Background Inhaled house dust mite (HDM) results in T-helper (TH) 2 type pathology in unsensitized mice, in conjunction with airway hyperreactivity and airway remodelling. However, the pulmonary cytokine and chemokine profile has not been reported. M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed5c110b76e723b32d8ca2facb2efe8
https://europepmc.org/articles/PMC3385347/
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje