Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jenna N. Lebedev"'
Autor:
Baodan Collins, James C. Zimring, Meghan Delaney, Xiaohong Wang, Lay See Er, Jenna N. Lebedev, Linda M. Kapp, Heather L. Howie
Publikováno v:
Transfusion. 60:1060-1068
Background Anti-red blood cell (RBC) alloantibodies consisting of only the immunoglobulin G (IgG) 4 subtype are typically considered clinically insignificant. A US Food and Drug Administration-approved monoclonal anti-human globulin (16H8) is nonreac
Autor:
David R. Gruber, James C. Zimring, Ariel M. Hay, Krystalyn E. Hudson, Xiaohong Wang, Amanda L. Richards, Heather L. Howie, Jenna N. Lebedev
Publikováno v:
Blood Advances. 4:1526-1537
Antibodies are typically thought of as the endpoint of humoral immunity that occur as the result of an adaptive immune response. However, affinity-matured antibodies can be present at the initiation of a new immune response, most commonly because of
Autor:
Jenna N. Lebedev, Linda M. Kapp, James C. Zimring, Krystalyn E. Hudson, Heather L. Howie, Xiaohong Wang
Publikováno v:
Journal of Immunological Methods. 455:10-13
Methods designed to monitor humoral immune responses, in a variety of settings, typically use a broadly reactive detection reagent (e.g. polyclonal anti-Ig (immunoglobulin)) in order to characterize antibody responses. In the context of murine models
Autor:
Gregory A. Denomme, Mairead B. Holton, Heather L. Howie, Selena Y. Cen, James C. Zimring, Beth Binnington, Donald R. Branch, Jenna N. Lebedev
Publikováno v:
TransfusionREFERENCES. 60(4)
BACKGROUND Human immunoglobulin G (hIgG) includes four different subtypes (IgG1, IgG2, IgG3, and IgG4). Due to genetic variations, each IgG subtype contains different isoallotypes. It was previously shown that a Food and Drug Administration-approved
Autor:
John D. Roback, Ariel M. Hay, Xiaoyun Fu, Hayley R. Waterman, Karen de Wolski, James C. Zimring, Heather L. Howie, Angelo D'Alessandro, Matthew S. Ranson, Jenna N. Lebedev, James D. Gorham, Peter C. Thomson, Rachel Culp-Hill
Red blood cells (RBCs) are the most numerous cell type in the body and serve a vital purpose of delivering oxygen to essentially all tissues. In addition to the central role of RBCs in health and disease, RBC storage is a requirement for the >90 mill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef0f64b1cd0db30a8e932ad8944ecb1
https://europepmc.org/articles/PMC6693009/
https://europepmc.org/articles/PMC6693009/
Autor:
Xiaohong Wang, Tamara C. Stegmann, Heather L. Howie, Jenna N. Lebedev, Yanyun Wu, James C. Zimring, James P. AuBuchon, Linda M. Kapp, Lay See Er, Gestur Vidarsson, Meghan Delaney
Publikováno v:
Transfusion. 56:2953-2962
BACKGROUND Human immunoglobulin G (IgG) includes four different subtypes (IgG1, IgG2, IgG3, and IgG4), and it is also now appreciated that there are genetic variations within IgG subtypes (called isoallotypes). Twenty-nine different isoallotypes have
Publikováno v:
Journal of clinical pathology. 71(6)
There are four subtypes of human IgG with different effector functions. Quantifying the relative amount of each IgG subtype is important for laboratory diagnosis in multiple settings. However, in an evolving landscape of the appreciation of human var
Autor:
Heather L. Howie, Lay See Er, Linda M. Kapp, Xiaohong Wang, Jenna N. Lebedev, James C. Zimring, Meghan Delaney
Publikováno v:
JCI Insight. 2
In recent years, the extent of our vulnerability to misinterpretation due to poorly characterized reagents has become an issue of great concern. Antibody reagents have been identified as a major source of error, contributing to the “reproducibility
Autor:
Tamara C. Stegmann, Jenna N. Lebedev, C. Ellen van der Schoot, Xiaohong Wang, Heather L. Howie, Hayley R. Waterman, Gestur Vidarsson, Linda M. Kapp, James C. Zimring, Ariel M. Hay
Publikováno v:
Blood. 128:21-21
Background: The administration of anti-D as an immune prophylaxis remains a great success in human immunotherapy; however, the mechanism of anti-D function remains unclear. Currently, anti-D is purified from plasma of D alloimmunized humans; 19 diffe