Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jenna M. Canfield"'
Autor:
Kimberly G. Laffey, Robert J. Stiles, Melissa J. Ludescher, Tessa R. Davis, Shariq S. Khwaja, Richard J. Bram, Peter J. Wettstein, Venkataraman Ramachandran, Christopher A. Parks, Edwin E. Reyes, Alejandro Ferrer, Jenna M. Canfield, Cory E. Johnson, Richard D. Hammer, Diana Gil, Adam G. Schrum
Publikováno v:
Proceedings of the National Academy of Sciences. 119
During normal T cell development in mouse and human, a low-frequency population of immature CD4−CD8−double-negative (DN) thymocytes expresses early, mature αβ T cell antigen receptor (TCR). We report that these early αβ TCR+ DN (EADN) cells a
Autor:
Tessa R. Davis, Aaron J. Johnson, Jamie Rossjohn, Mark A. Daniels, Alejandro Ferrer, Adam G. Schrum, Deanne Hebrink, Kevin D. Pavelko, Stephen E. P. Smith, Jenna M. Canfield, Katelynn M. Wilton, Peter J. Wettstein, Dietmar J. Kappes, Diana Gil, Larry R. Pease, Scott R. Burrows, James McCluskey, April M. Huseby Kelcher, Claudia Neuhauser, Zhenjun Chen, Steven C. Neier, Eva M. Carmona, Andrew H. Limper, Robert J. Stiles
Publikováno v:
Sci Immunol
During αβ T cell development, T cell antigen receptor (TCR) engagement transduces biochemical signals through a protein-protein interaction (PPI) network that dictates dichotomous cell fate decisions. It remains unclear how signal specificity is co
Autor:
Jenna M Canfield, Alejandro Ferrer, Steven C Neier, Katelynn M Wilton, Robert J Stiles, Tessa Davis, Adam G Schrum, Diana Gil Pages
Publikováno v:
The Journal of Immunology. 204:61.15-61.15
Upon positive selection of conventional αβ T cells, CD4+ CD8+ double-positive (DP) cells transition to single-positive (SP) and reduce their responsiveness to weak peptide/MHC ligands (affinity threshold conversion, ATC). We report that ATC actuall
Autor:
Neier, Steven C., Ferrer, Alejandro, Wilton, Katelynn M., Smith, Stephen E. P., Kelcher, April M. H., Pavelko, Kevin D., Canfield, Jenna M., Davis, Tessa R., Stiles, Robert J., Chen, Zhenjun, McCluskey, James, Burrows, Scott R., Rossjohn, Jamie, Hebrink, Deanne M., Carmona, Eva M., Limper, Andrew H., Kappes, Dietmar J., Wettstein, Peter J., Johnson, Aaron J., Pease, Larry R.
Publikováno v:
Science Immunology; 2019, Vol. 4 Issue 32, p1-15, 15p