Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jenna M Gaska"'
Publikováno v:
eLife, Vol 8 (2019)
The restricted host tropism of hepatitis C virus (HCV) remains incompletely understood, especially post-entry, and has hindered developing an immunocompetent, small animal model. HCV replication in non-permissive species may be limited by incompatibi
Externí odkaz:
https://doaj.org/article/3f20b41a2f924998a2ea491a773599b0
Autor:
Florian Douam, Carly G. K. Ziegler, Gabriela Hrebikova, Bruno Fant, Robert Leach, Lance Parsons, Wei Wang, Jenna M. Gaska, Benjamin Y. Winer, Brigitte Heller, Alex K. Shalek, Alexander Ploss
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Humanized mice are an enabling technology to explore human immunity and disease. Here, Douam et al. provide an in-depth comparison of immune responses to yellow fever vaccine in human vaccinees, conventional and second-generation humanized mice and d
Externí odkaz:
https://doaj.org/article/74919627ccd0481f9143428c27498c08
Autor:
Yaron Bram, Amit Parekh, Gabriel Lipkowitz, Robert E. Schwartz, Rohit Jindal, Benjamin Y. Winer, Eric Novik, Lance Parsons, Cheul H. Cho, Jenna M. Gaska, Anil B. Shrirao, Alexander Ploss, Robert W. Leach
Publikováno v:
Hepatology
Hepatitis B virus (HBV) remains a major global health problem with 257 million chronically infected individuals worldwide, of whom approximately 20 million are co-infected with hepatitis delta virus (HDV). Progress toward a better understanding of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8853c2e395d1141d4070f15ee34d18
https://doi.org/10.1002/hep.30815
https://doi.org/10.1002/hep.30815
Autor:
Mikhail M. Savitski, Hahn Kim, Ila Nimgaonkar, Mohammad Shahrad, Andrew R. Berneshawi, Nicholas F. Archer, Javier Caballero-Gómez, Qiang Ding, Alexander Ploss, Florian Douam, Jenna M. Gaska, André Mateus, Isabelle Becher, Robert A. LeDesma
Publikováno v:
Antiviral Res
Hepatitis E virus (HEV) causes 14 million infections and 60,000 deaths per year globally, with immunocompromised persons and pregnant women experiencing severe symptoms. Although ribavirin can be used to treat chronic hepatitis E, toxicity in pregnan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e5e1557dc3022db81100977e1bed73
https://pubmed.ncbi.nlm.nih.gov/33326835
https://pubmed.ncbi.nlm.nih.gov/33326835
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
The restricted host tropism of hepatitis C virus (HCV) remains incompletely understood, especially post-entry, and has hindered developing an immunocompetent, small animal model. HCV replication in non-permissive species may be limited by incompatibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24dd081f061bfbe66eb2400e6e43613
http://europepmc.org/articles/PMC6510530
http://europepmc.org/articles/PMC6510530
Publikováno v:
Methods in Molecular Biology ISBN: 9781493989751
In spite of the immense progress in hepatitis C virus (HCV) research, efforts to prevent infection, such as generating a vaccine, have not yet been successful. The high price tag associated with current treatment options for chronic infection and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a2175175cb0a4aff2f2839cd4091fb
https://pubmed.ncbi.nlm.nih.gov/30593647
https://pubmed.ncbi.nlm.nih.gov/30593647
Autor:
Bruno Fant, Robert W. Leach, Gabriela Hrebikova, Wei Wang, Brigitte Heller, Lance Parsons, Alexander Ploss, Florian Douam, Alex K. Shalek, Benjamin Y. Winer, Jenna M. Gaska, Carly G. K. Ziegler
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Nature Communications
Nature Communications
Mice engrafted with components of a human immune system have become widely-used models for studying aspects of human immunity and disease. However, a defined methodology to objectively measure and compare the quality of the human immune response in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6791b32ea534df8214b5370b74c5ce96
https://doi.org/10.1038/s41467-018-07478-2
https://doi.org/10.1038/s41467-018-07478-2
Autor:
David J. Kim, Metodi Balev, Qiang Ding, Jenna M. Gaska, Alexander Ploss, Florian Douam, Brigitte Heller, Lei Wei
Publikováno v:
Proceedings of the National Academy of Sciences. 115
The limited host tropism of numerous viruses causing disease in humans remains incompletely understood. One example is Zika virus (ZIKV), an RNA virus that has reemerged in recent years. Here, we demonstrate that ZIKV efficiently infects fibroblasts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21cd1afc47ae33d224d20c1d17d5fd93
https://doi.org/10.1073/pnas.1803406115
https://doi.org/10.1073/pnas.1803406115
Autor:
Maria E. Cuevas, Andrea C Gist, Jenna M Gaska, Maria C. Todd, Jonathan M. King, Rebecca A. Sheller
Publikováno v:
International Journal of Oncology. 47:650-656
Endometrial cancer is the most common female reproductive cancer in the United States and is associated with deregulated tight junction protein expression. Given the highly estrogen-responsive nature of this tissue, we investigated the effects of est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c503e3591a089fb5d244d4870de61a32
https://doi.org/10.3892/ijo.2015.3030
https://doi.org/10.3892/ijo.2015.3030