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pro vyhledávání: '"Jenna Lanz"'
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 524 (2023)
Background: Since disulfiram’s discovery in the 1940s and its FDA approval for alcohol use disorder, other indications have been investigated. This review describes potential clinical applications, associated risks, and challenges. Methods: For thi
Externí odkaz:
https://doaj.org/article/8af47cae887f446e9176015535091083
Autor:
Xiaohong Zhao, Lois E. Greene, Daniel C. Masison, Evgeny E. Bezsonov, Tyler Pease, Elena D. Staguhn, Jenna Lanz, Joseph M. Ahearn, Danielle N. Steinberg, Evan Eisenberg
Publikováno v:
The Journal of biological chemistry. 293(9)
The [URE3] yeast prion is the self-propagating amyloid form of the Ure2 protein. [URE3] is cured by overexpression of several yeast proteins, including Ydj1, Btn2, Cur1, Hsp42, and human DnaJB6. To better understand [URE3] curing, we used real-time i