Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jenna K. Shagoury"'
Autor:
Metin Ozata, Jenna K. Shagoury, Frances J. Hayes, Kathryn A. Martin, Stephanie B. Seminara, Corrine K. Welt, Nelly Pitteloud, Pierre Bouloux, Andrew A. Dwyer, Guy Van Vliet, Felecia Cerrato, Milena Králíčková, John L. Falardeau, Janet E. Hall
Publikováno v:
European Journal of Endocrinology. 155:S3-S10
Objective: To determine the frequency of rare nucleotide variants in GNRHR and GPR54 in a large cohort of probands (n = 166) with normosmic idiopathic hypogonadotropic hypogonadism (nIHH), characterized by mode of inheritance, testicular volume, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2608f7b8b987dc8822b69caae2c9c77
https://doi.org/10.1530/eje.1.02235
https://doi.org/10.1530/eje.1.02235
Autor:
Jenna K. Shagoury, Kristine M. Schwinof, John Dixon, James S. Acierno, Rosemary R. Thresher, Stephen O'Rahilly, Yousef Bo-Abbas, Samuel Aparicio, Susan A. Slaugenhaupt, Ursula B. Kaiser, William H. Colledge, Mark Carlton, Stephanie B. Seminara, James F. Gusella, Wendy Kuohung, William F. Crowley, Emmanouella E. Chatzidaki, Sophie Messager, Alan G. Hendrick, Dirk Zahn
Publikováno v:
New England Journal of Medicine. 349:1614-1627
Puberty, a complex biologic process involving sexual development, accelerated linear growth, and adrenal maturation, is initiated when gonadotropin-releasing hormone begins to be secreted by the hypothalamus. We conducted studies in humans and mice t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd22f68a8813be33087d9bfa72db5af
https://doi.org/10.1056/nejmoa035322
https://doi.org/10.1056/nejmoa035322
Autor:
Yousef Bo-Abbas, Stephanie B. Seminara, Jenna K. Shagoury, James S. Acierno, William F. Crowley
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 88:2947-2950
Idiopathic hypogonadotropic hypogonadism (IHH) is traditionally established by 1) the absence of spontaneous pubertal development by age 18 yr and 2) low sex steroids with inappropriately low gonadotropins in the absence of any functional or anatomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58252adf83120f7b796bc77d8f1657f8
https://doi.org/10.1210/jc.2003-030423
https://doi.org/10.1210/jc.2003-030423
Autor:
Ursula B. Kaiser, John Dixon, James S. Acierno, James F. Gusella, Jenna K. Shagoury, Yousef Bo-Abbas, Wendy Kuohung, Susan A. Slaugenhaupt, Samuel Aparicio, William H. Colledge, Mark Carlton, Kristine M. Schwinof, Sophie Messager, Stephanie B. Seminara, Rosemary R. Thresher, Alan G. Hendrick, William F. Crowley, Emmanouella E. Chatzidaki, Dirk Zahn, Stephen O'Rahilly
Publikováno v:
Obstetrical & Gynecological Survey. 59:351-353
The first known step in sexual maturation at puberty is the secretion of gonadotropin-releasing hormone (GnRH) by the hypothalamus. Pubertal changes also include accelerated linear growth and adrenal maturation. The authors used complementary genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6845a570b508aef72503965279957c41
https://doi.org/10.1097/00006254-200405000-00020
https://doi.org/10.1097/00006254-200405000-00020
Autor:
Yousef Bo-Abbas, James S. Acierno, Jenna K. Shagoury, William F. Crowley, Stephanie B. Seminara
Publikováno v:
The Journal of clinical endocrinology and metabolism. 88(6)
Failure of the normal pattern of episodic secretion of GnRH from the hypothalamus results in the clinical syndrome of idiopathic hypogonadotropic hypogonadism (IHH), with failure of pubertal development and infertility. The only gene that has been im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8d2b3a2f0743e8eea7df6e33074bb1
https://pubmed.ncbi.nlm.nih.gov/12788881
https://pubmed.ncbi.nlm.nih.gov/12788881