Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jenna Hanmer"'
Autor:
Martin Citron, Tracey K. Murray, Peter Davies, Su Wu, Helen Sims, Jenna Hanmer, Xiyun Chai, Michael J. O'Neill, Michael Hutton, Claire V. Cella, Nicola Buckner, Robert D. Kinley
Publikováno v:
Journal of Biological Chemistry. 286:34457-34467
The microtubule-associated protein Tau plays a critical role in the pathogenesis of Alzheimer disease and several related disorders (tauopathies). In the disease Tau aggregates and becomes hyperphosphorylated forming paired helical and straight filam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70c6c1847bf92bf99c636ffa25905231
https://doi.org/10.1074/jbc.m111.229633
https://doi.org/10.1074/jbc.m111.229633
Autor:
Claire V. Cella, Jenna Hanmer, Michael Hutton, David O. Calligaro, Aaron Simmons, Annalisa Cavallini, Peter Davies, Hugh Nuthall, Laura J. Bloem, Philip G. Szekeres, Michael J. O'Neill, Suchira Bose, Mark A Ward, Helen Sims, Jeff W. Cramer, Tracey K. Murray, Elizabeth Eberle, Lisa Baschirotto, Dan L. Czilli, Ana I. Mateo, Michel Goedert, Sandra Sossick
Publikováno v:
Alzheimer's & Dementia. 8
Background: Neurofibrillary tangles (NFT), one of the hallmarks of Alzheimer’s disease (AD), are composed of paired helical filaments (PHF) of abnormally hyperphosphorylated tau. The accumulation of these proteinaceous aggregates in AD correlates w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dd9969eb4a5cb1687792eeaf6cea0ba
https://doi.org/10.1016/j.jalz.2012.05.1243
https://doi.org/10.1016/j.jalz.2012.05.1243