Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jenna Guthmiller"'
Autor:
Jenna Guthmiller, Linda Yu-Ling Lan, Lei Li, Carole Henry, Christopher Stamper, Henry Utset, Alec Freyn, Julianna Han, Olivia Stovicek, Jiaolong Wang, Nai-Ying Zheng, Min Huang, Haley Dugan, Micah Tepora, Xueyong Zhu, Yao-Qing Chen, Anna-Karin Palm, Dustin Shaw, Madhumanthi Loganathan, Benjamin Francis, Mia McNair, Philip Mead, Ian Wilson, Adolfo Garcia-Sastre, Raffael Nachbagauer, Peter Palese, Andrew Ward, Lynda Coughlan, Florian Krammer, Patrick Wilson
In a phase I clinical trial, the chimeric hemagglutinin (cHA) immunogen induced antibody responses against the conserved HA stalk domain. However, the landscape of the B cell specificities and subsets induced by this vaccine remain undetermined. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de79b74f725fd6cd48343f3ef38289c0
https://doi.org/10.21203/rs.3.rs-2600472/v1
https://doi.org/10.21203/rs.3.rs-2600472/v1
Autor:
Jenna Guthmiller, Lei Li, Linda Yu-Ling Lan, Carole Henry, Christopher Stamper, Alec Freyn, Henry Utset, Julianna Han, Peter Palese, Lynda Coughlan, Andrew Ward, Florian Krammer, Patrick C Wilson
Publikováno v:
The Journal of Immunology. 208:126.32-126.32
Seasonal influenza virus vaccines provide modest protection against endemic viruses but lack effectiveness against pandemic-threat viruses. Therefore, new immunogens and vaccine platforms that induce antibodies against broadly protective epitopes are
Autor:
Linda (Yu-Ling) Lan, Lei Li, Min Huang, Carole Henry, Nai-Ying Zheng, Yao-Qing Chen, Mahalia McNair, Philip Meade, Jenna Guthmiller, Haley Dugan, Micah Tepora, Anna-Karin Palm, Dustin Shaw, Christopher Stamper, Aly Azeem Khan, Raffael Nachbagauer, Adolfo García-Sastre, Peter Palese, Florian Krammer, Patrick C Wilson
Publikováno v:
The Journal of Immunology. 204:245.3-245.3
A universal influenza virus vaccine candidate trial was recently conducted that utilized novel influenza viruses expressing chimeric hemagglutinin (HA) proteins. The chimeric HAs present in the vaccines are composed of a typical stalk domain (from an
Publikováno v:
The Journal of Immunology. 196:134.4-134.4
Plasmodium infections cause malaria, which remains a global public health crisis. Germinal center derived anti-Plasmodium antibody responses are essential for control of blood-stage parasite replication and clearance. However, antibody responses are
Autor:
Ryan Zander, Nyamekye Obeng-Adjei, Jenna Guthmiller, Divine Kulu, Jun Li, Aissata Ongoiba, Boubacar Traore, Peter Crompton, Noah Butler
Publikováno v:
The Journal of Immunology. 194:137.5-137.5
Pathogen-specific T cells are subject to co-stimulatory and co-inhibitory signals, the balance of which promotes pathogen control while limiting immunopathology. During blood-stage Plasmodium infection, parasite-specific CD4 T cells express PD-1 and