Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jenna Geddes Sweeney"'
Autor:
Jenna Geddes Sweeney, Jennifer Liang, Aristotelis Antonopoulos, Nicholas Giovannone, Shuli Kang, Tony S. Mondala, Steven R. Head, Sandra L. King, Yoshihiko Tani, Danielle Brackett, Anne Dell, George F. Murphy, Stuart M. Haslam, Hans R. Widlund, Charles J. Dimitroff
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Aberrant glycosylation patterns on cancer cells promote several pro-tumorigenic functions, including enhancing tumor cell proliferation. Here the authors provide data that show melanoma cells downregulate GCNT2 with consequent loss of I-branched glyc
Externí odkaz:
https://doaj.org/article/de097a28a8eb4a7595203ca85b7c7bc9
Autor:
Nicholas Giovannone, Aristotelis Antonopoulos, Jennifer Liang, Jenna Geddes Sweeney, Matthew R. Kudelka, Sandra L. King, Gi Soo Lee, Richard D. Cummings, Anne Dell, Steven R. Barthel, Hans R. Widlund, Stuart M. Haslam, Charles J. Dimitroff
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Germinal centers (GC) are microanatomical niches where B cells proliferate, undergo antibody affinity maturation, and differentiate to long-lived memory B cells and antibody-secreting plasma cells. For decades, GC B cells have been defined by their r
Externí odkaz:
https://doaj.org/article/63a75e84f9e2408c97b0768fa5fe2f1f
Autor:
Xiaodong Jiang, Chang Ook Park, Jenna Geddes Sweeney, Min Jae Yoo, Olivier Gaide, Thomas Seth Kupper
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169397 (2017)
The role of mouse dermal γδ T cells in inflammatory skin disorders and host defense has been studied extensively. It is known that dendritic epidermal T cells (DETC) have a monomorphic γδ T cell receptor (TCR) and reside in murine epidermis from
Externí odkaz:
https://doaj.org/article/c314de6da53d4f5497a8f80434081912
Autor:
Steven R. Barthel, Matthew R. Ramsey, Thomas S. Kupper, George F. Murphy, Christine G. Lian, Christoph Schlapbach, Jennifer Landsberg, Martin C. Mihm, Charles J. Dimitroff, Jennifer Liang, Anne Brandenburg, Kate Stewart, Jenna Geddes-Sweeney, Markus V. Heppt, Kyla Mucciarone, Mariana Silva, Praveen Singh, Erik Rasbach, Christina Martins, Yuta Itoh, Tobias Schatton
T-cell immunoglobulin mucin family member 3 (Tim-3) is an immune checkpoint receptor that dampens effector functions and causes terminal exhaustion of cytotoxic T cells. Tim-3 inhibitors are under investigation in immuno-oncology (IO) trials, because
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::997588a1168fc6e4daee8e1fd7d501a6
https://doi.org/10.1158/0008-5472.c.6514280.v1
https://doi.org/10.1158/0008-5472.c.6514280.v1
Autor:
Steven R. Barthel, Matthew R. Ramsey, Thomas S. Kupper, George F. Murphy, Christine G. Lian, Christoph Schlapbach, Jennifer Landsberg, Martin C. Mihm, Charles J. Dimitroff, Jennifer Liang, Anne Brandenburg, Kate Stewart, Jenna Geddes-Sweeney, Markus V. Heppt, Kyla Mucciarone, Mariana Silva, Praveen Singh, Erik Rasbach, Christina Martins, Yuta Itoh, Tobias Schatton
Supplementary Data from Inhibition of Melanoma Cell–Intrinsic Tim-3 Stimulates MAPK-Dependent Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ae4e8e7422664ac2bb35f1c79054cf
https://doi.org/10.1158/0008-5472.22432958
https://doi.org/10.1158/0008-5472.22432958
Autor:
Jenna Geddes Sweeney, Xiaodong Jiang, Min Jae Yoo, Olivier Gaide, Chang Ook Park, Thomas S. Kupper
Publikováno v:
PLoS ONE
PloS one, vol. 12, no. 1, pp. e0169397
PLoS ONE, Vol 12, Iss 1, p e0169397 (2017)
PloS one, vol. 12, no. 1, pp. e0169397
PLoS ONE, Vol 12, Iss 1, p e0169397 (2017)
The role of mouse dermal γδ T cells in inflammatory skin disorders and host defense has been studied extensively. It is known that dendritic epidermal T cells (DETC) have a monomorphic γδ T cell receptor (TCR) and reside in murine epidermis from
Autor:
Nicholas Giovannone, Jenna Geddes Sweeney, Jennifer Liang, Aristotelis Antonopoulos, Stephen M Pochebit, Neil Bhattacharyya, Steven R. Barthel, Stuart M. Haslam, Charles J Dimitroff
Publikováno v:
The Journal of Immunology. 196:124.28-124.28
Activated leukocytes commonly remodel cell surface carbohydrates (glycans) in order to modulate lectin-glycoprotein interactions involved in trafficking, adhesion, antigen receptor signaling, and cell fate. Because germinal center (GC) B cells upregu
Autor:
Jenna Geddes Sweeney, Jennifer Liang, Nicholas Giovannone, Lana Schaffer, Steven R. Head, Aristotelis Antonopoulos, Stuart M. Haslam, Hans R. Widlund, Charles J Dimitroff
Publikováno v:
The Journal of Immunology. 196:144.17-144.17
Malignant transformation is often associated with aberrant glycosylation of cell surface proteins. Commonly observed changes in glycan structures include increased presence of sialic acid, altered expression of mucins, and abnormal branching of N-gly