Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jenna A. Wood"'
Autor:
Li Gan, Leslie C.L. Wu, Jenna A. Wood, Monica Yao, Chris M. Treleaven, Nelsa L. Estrella, Bruce M. Wentworth, Gunnar J. Hanson, Marco A. Passini
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 17-27 (2022)
Antisense RNA technology is a strategy for the treatment of Duchenne muscular dystrophy (DMD), a progressive and universally fatal X-linked neuromuscular disease caused by frameshift mutations in the gene encoding dystrophin. Phosphorodiamidate morph
Externí odkaz:
https://doaj.org/article/bddb1e4b922e426fa81d57fe314dc534
Autor:
Eva M. López-Vidal, Carly K. Schissel, Somesh Mohapatra, Kamela Bellovoda, Chia-Ling Wu, Jenna A. Wood, Annika B. Malmberg, Andrei Loas, Rafael Gómez-Bombarelli, Bradley L. Pentelute
Publikováno v:
JACS Au, Vol 1, Iss 11, Pp 2009-2020 (2021)
Externí odkaz:
https://doaj.org/article/cd02882331b944c98c796971667fec2e
Autor:
Chia-Ling Wu, Annika B. Malmberg, Jenna A. Wood, Andrei Loas, Kamela Bellovoda, Eva M. López-Vidal, Carly K. Schissel, Somesh Mohapatra, Bradley L. Pentelute, Rafael Gómez-Bombarelli
Publikováno v:
JACS Au, Vol 1, Iss 11, Pp 2009-2020 (2021)
JACS Au
JACS Au
Therapeutic macromolecules such as proteins and oligonucleotides can be highly efficacious but are often limited to extracellular targets due to the cell's impermeable membrane. Cell-penetrating peptides (CPPs) are able to deliver such macromolecules
Autor:
Somesh Mohapatra, Chia-Ling Wu, Annika B. Malmberg, Kamela Bellovoda, Andrei Loas, Colin M. Fadzen, Rafael Gómez-Bombarelli, Jenna A. Wood, Carly K. Schissel, Justin M. Wolfe, Bradley L. Pentelute
Publikováno v:
Nat Chem
There are more amino acid permutations within a 40-residue sequence than atoms on Earth. This vast chemical search space hinders the use of human learning to design functional polymers. Here we show how machine learning enables the de novo design of
Autor:
Rafael Gómez-Bombarelli, Andrei Loas, Somesh Mohapatra, Chia-Ling Wu, Colin M. Fadzen, Carly K. Schissel, Annika B. Malmberg, Justin M. Wolfe, Kamela Bellovoda, Bradley L. Pentelute, Jenna A. Wood
There are more amino acid permutations within a 40-residue sequence than atoms on Earth. This vast chemical search space hinders the use of human learning to design functional polymers. Here we couple supervised and unsupervised deep learning with hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c093b86f73cfa35cae5d339b2727c067
https://doi.org/10.1101/2020.04.10.036566
https://doi.org/10.1101/2020.04.10.036566