Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability.

Autor: Caballero-Ruiz B; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy., Gkotsi DS; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS29JT, UK., Ollerton H; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS29JT, UK., Morales-Alcala CC; Leeds Institute for Medical Research, School of Medicine, University of Leeds, Leeds LS29JT, UK., Bordone R; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy., Jenkins GML; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS29JT, UK., Di Magno L; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy., Canettieri G; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.; Institute Pasteur Italy-Cenci Bolognetti Foundation, 00161 Rome, Italy., Riobo-Del Galdo NA; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS29JT, UK.; Leeds Institute for Medical Research, School of Medicine, University of Leeds, Leeds LS29JT, UK.; Leeds Cancer Research Centre, University of Leeds, Leeds LS29JT, UK.; Astbury Centre for Structural and Molecular Biology, University of Leeds, Leeds LS29JT, UK.

Publikováno v: Cancers [Cancers (Basel)] 2023 Jan 06; Vol. 15 (2). Date of Electronic Publication: 2023 Jan 06.