Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jenina Kingma"'
Autor:
Sebastian Hendrix, Vincent Dartigue, Hailee Hall, Shrankhla Bawaria, Jenina Kingma, Bilkish Bajaj, Noam Zelcer, Daniel L. Kober
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Site-one protease (S1P) conducts the first of two cleavage events in the Golgi to activate Sterol regulatory element binding proteins (SREBPs) and upregulate lipogenic transcription. S1P is also required for a wide array of additional signal
Externí odkaz:
https://doaj.org/article/37ed8873d23d4923aecc3d62781541c8
Autor:
Sebastian Hendrix, Jenina Kingma, Roelof Ottenhoff, Masoud Valiloo, Monika Svecla, Lobke F. Zijlstra, Vinay Sachdev, Kristina Kovac, Johannes H. M. Levels, Aldo Jongejan, Jan F. de Boer, Folkert Kuipers, Antoine Rimbert, Giuseppe D. Norata, Anke Loregger, Noam Zelcer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The sterol regulatory element binding proteins (SREBPs) are transcription factors that govern cholesterol and fatty acid metabolism. We recently identified SPRING as a post-transcriptional regulator of SREBP activation. Constitutive or induc
Externí odkaz:
https://doaj.org/article/3f5880a3788d4aad95e74419033308ec
Autor:
Suzanne A.E. van Wouw, Marlene van den Berg, Maroua El Ouraoui, Amber Meurs, Jenina Kingma, Roelof Ottenhoff, Melanie Loix, Marten A. Hoeksema, Koen Prange, Gerard Pasterkamp, Jerome J.A. Hendriks, Jeroen F.J. Bogie, Jan B. van Klinken, Frederic M. Vaz, Aldo Jongejan, Menno P.J. de Winther, Noam Zelcer
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 2, Pp 100325- (2023)
Lysoplasmalogens are a class of vinyl ether bioactive lipids that have a central role in plasmalogen metabolism and membrane fluidity. The liver X receptor (LXR) transcription factors are important determinants of cellular lipid homeostasis owing to
Externí odkaz:
https://doaj.org/article/5be45c9062f1454c8a49dcd0a8d8b7ff
Autor:
Pomme M.F. Rigter, Ilse Wallaard, Mehrnoush Aghadavoud Jolfaei, Jenina Kingma, Laura Post, Minetta Elgersma, Ype Elgersma, Geeske M. van Woerden
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105303- (2022)
Summary: With the recent findings that mutations in the gene encoding the α-subunit of calcium/calmodulin-dependent protein kinase II (CAMK2A) causes a neurodevelopmental disorder (NDD), it is of great therapeutic relevance to know if there exists a
Externí odkaz:
https://doaj.org/article/dd5c51f304d94eef9eb2bbf67e5f8829
Autor:
Monica Sonzogni, Ilse Wallaard, Sara Silva Santos, Jenina Kingma, Dorine du Mee, Geeske M. van Woerden, Ype Elgersma
Publikováno v:
Molecular Autism, Vol 9, Iss 1, Pp 1-19 (2018)
Abstract Background Angelman syndrome (AS) is a neurodevelopmental disorder caused by mutations affecting UBE3A function. AS is characterized by intellectual disability, impaired motor coordination, epilepsy, and behavioral abnormalities including au
Externí odkaz:
https://doaj.org/article/47ddba8f847a4d07bb0e7241bd603d15
Autor:
Pomme M F, Rigter, Ilse, Wallaard, Mehrnoush, Aghadavoud Jolfaei, Jenina, Kingma, Laura, Post, Minetta, Elgersma, Ype, Elgersma, Geeske M, van Woerden
Publikováno v:
iScience. 25(11)
With the recent findings that mutations in the gene encoding the α-subunit of calcium/calmodulin-dependent protein kinase II (CAMK2A) causes a neurodevelopmental disorder (NDD), it is of great therapeutic relevance to know if there exists a critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::503eb7baad2dbfb0af3fb7c8e34887e6
https://pubmed.ncbi.nlm.nih.gov/36304100
https://pubmed.ncbi.nlm.nih.gov/36304100
Autor:
Jessica K. Nelson, Nienke M. van Loon, Noam Zelcer, Martina Moeton, Suzanne A.E. van Wouw, Roelof Ottenhoff, Saskia Scheij, Jenina Kingma
Publikováno v:
Atherosclerosis, 315, 1-9. Elsevier Ireland Ltd
Background and aims Cholesterol metabolism is tightly regulated by transcriptional and post-transcriptional mechanisms. Accordingly, dysregulation of cholesterol metabolism is a major risk factor for the development of coronary artery disease and ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aadca31bfc399e7a7a2573f7b82e1a09
https://pure.amc.nl/en/publications/regulation-of-intestinal-ldlr-by-the-lxridol-axis(6a64ee1d-17dd-474a-a545-fbf6e6d967c8).html
https://pure.amc.nl/en/publications/regulation-of-intestinal-ldlr-by-the-lxridol-axis(6a64ee1d-17dd-474a-a545-fbf6e6d967c8).html
Autor:
Ype Elgersma, Ilse Wallaard, Geeske M. van Woerden, Dorine du Mee, Monica Sonzogni, Sara Silva Santos, Jenina Kingma
Publikováno v:
Molecular Autism, 9:47. BioMed Central Ltd.
Molecular Autism
Molecular Autism, Vol 9, Iss 1, Pp 1-19 (2018)
Molecular Autism
Molecular Autism, Vol 9, Iss 1, Pp 1-19 (2018)
Background Angelman syndrome (AS) is a neurodevelopmental disorder caused by mutations affecting UBE3A function. AS is characterized by intellectual disability, impaired motor coordination, epilepsy, and behavioral abnormalities including autism spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbbb841013f6581d6127b964aa3de9f
https://doi.org/10.1186/s13229-018-0231-7
https://doi.org/10.1186/s13229-018-0231-7