Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jenifer Sanchez"'
Autor:
Molly S. George, Jenifer Sanchez, Christina Rollings, David Fear, Peter Irving, Linda V. Sinclair, Anna Schurich
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107280- (2023)
Summary: Long-term T cell dysregulation has been reported following COVID-19 disease. Prolonged T cell activation is associated with disease severity and may be implicated in producing long-covid symptoms. Here, we assess the role of extracellular ve
Externí odkaz:
https://doaj.org/article/9b2cfbbd5b5749df90f2b4881f8ed95b
Autor:
Sophie L. M. Walker, Chand Muthoo, Jenifer Sanchez, Ana Gutierrez Del Arroyo, Gareth L. Ackland
Publikováno v:
Intensive Care Medicine Experimental, Vol 10, Iss 1, Pp 1-20 (2022)
Take-home message Sex differences in sepsis are underexplored, even though female sex appears to be cardioprotective in early sepsis. In early normovolaemic polymicrobial sepsis, hyperdynamic response occurs in males, whereas myocardial stress/injury
Externí odkaz:
https://doaj.org/article/63be37f961f54a658011efacee195293
Autor:
Ana Gutierrez del Arroyo, Anna Hadjihambi, Jenifer Sanchez, Egor Turovsky, Vitaly Kasymov, David Cain, Tom D. Nightingale, Simon Lambden, Seth G.N. Grant, Alexander V. Gourine, Gareth L. Ackland
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 457-469 (2019)
Background: Neutrophil depletion improves neurologic outcomes in experimental sepsis/brain injury. We hypothesized that neutrophils may exacerbate neuronal injury through the release of neurotoxic quantities of the neurotransmitter glutamate. Methods
Externí odkaz:
https://doaj.org/article/0aaa2e17d6344966b236b4d45e768b8f
Publikováno v:
Metabolites, Vol 10, Iss 11, p 461 (2020)
Upon activation T cells engage glucose metabolism to fuel the costly effector functions needed for a robust immune response. Consequently, the availability of glucose can impact on T cell function. The glucose concentrations used in conventional cult
Externí odkaz:
https://doaj.org/article/ea55f4116ae14ec99f692e3abf13988f
Autor:
Laura J. Pallett, Leo Swadling, Mariana Diniz, Alexander A. Maini, Marius Schwabenland, Adrià Dalmau Gasull, Jessica Davies, Stephanie Kucykowicz, Jessica K. Skelton, Niclas Thomas, Nathalie M. Schmidt, Oliver E. Amin, Upkar S. Gill, Kerstin A. Stegmann, Alice R. Burton, Emily Stephenson, Gary Reynolds, Matt Whelan, Jenifer Sanchez, Roel de Maeyer, Clare Thakker, Kornelija Suveizdyte, Imran Uddin, Ana M. Ortega-Prieto, Charlotte Grant, Farid Froghi, Giuseppe Fusai, Sabela Lens, Sofia Pérez-del-Pulgar, Walid Al-Akkad, Giuseppe Mazza, Mahdad Noursadeghi, Arne Akbar, Patrick T. F. Kennedy, Brian R. Davidson, Marco Prinz, Benjamin M. Chain, Muzlifah Haniffa, Derek W. Gilroy, Marcus Dorner, Bertram Bengsch, Anna Schurich, Mala K. Maini
Publikováno v:
Nature. 614:334-342
Autor:
Laura J. Pallett, Mariana Diniz, Leo Swadling, Jessica Skelton, Alexander Maini, Jessica Davies, Stephanie Kucykowicz, Nathalie Schmidt, Oliver E. Amin, Upkar Gill, Alice Burton, Jenifer Sanchez, Giuseppe Fusai, Sabela Lens, Sofía Pérez-del-Pulgar, Patrick Kennedy, Brian R. Davidson, Muzlifah Haniffa, Derek Gilroy, Marcus Dorner, Anna Schurich, Mala Maini
Publikováno v:
Journal of Hepatology. 77:S55-S56
Autor:
Ian Jackson, Graham M. Lord, Jenifer Sanchez, Richard G. Jenner, Omer Serhan Omer, Rimma Goldberg, Luke B. Roberts, Natalie J. Prescott, Jennie Clough, Nedyalko Petrov, Peter M. Irving, Anna Appios, Shahram Kordasti, Miles Parkes, Arnulf Hertweck, Scott David Tasker, Anna Lorenc
Publikováno v:
Journal of Crohn's & Colitis
Background and Aims Differential responsiveness to interleukin [IL]-2 between effector CD4+ T cells [Teff] and regulatory T cells [Treg] is a fundamental mechanism of immunoregulation. The single nucleotide polymorphism [SNP] rs61839660, located with
Autor:
S. Sodha, Anna L. David, S. Ciechanowicz, Pervez Sultan, C. Cubillos, J. Dick, Anna Reyes, Saavan Patel, R. Fernando, Jenifer Sanchez, E. Olearo, Gareth L. Ackland, A. Stewart, A.G. Del Arroyo, A. Reeve, S. Phillips
Publikováno v:
British Journal of Anaesthesia. 122:92-102
Background Epidural-related maternal fever (ERMF) has been reported in ∼26% of labouring women. The underlying mechanisms remain unclear. We hypothesised that ERMF is promoted by bupivacaine disrupting cytokine production/release from mononuclear l
Autor:
Tamara Muliaditan, Leena Halim, Lynsey May Whilding, Benjamin Draper, Daniela Yordanova Achkova, Fahima Kausar, Maya Glover, Natasha Bechman, Appitha Arulappu, Jenifer Sanchez, Kristina Grigoriadis, Kushal Kumar Das, Andrea Candelli, Daniel Larcombe-Young, Caroline Malai Hull, Richard Buus, Peter Gordon, Anita Grigoriadis, David Marc Davies, Anna Schurich, John Maher
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
European Heart Journal. 40
Purpose Tumour necrosis factor alpha (TNFα) regulates both normal and pathophysiological cardiac function. The regulatory role of TNFα derived from different sources (leukocyte versus cardiac cells) in cardiac physiology is unclear. Deficiency of i